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第十屆生物物理新知研討會
The 10th Symposium on Recent Advances in Biophysics |
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時 間：5月24日至28日
地 點：清華大學生命科學院、同步輻射研究中心
主辦單位：本院生物化學研究所、台灣生物物理學會、清華大學生命科學院、同步輻射研究中心
議 程（暫訂）
Tuesday, May 24
Workshop at NCHC
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09:30-10:30
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Docking, Scoring, and Chemical Databases
Jung-Hsin Lin,
Medical College of National Taiwan University |
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10:50-12:00
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Hierarchical Virtual Screening and Lead Optimization
Jung-Hsin
Lin, Medical College of National Taiwan University |
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13:30-16:30
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Application of Computer-Aided Drug Design
Hands-On Course in Drug
Discovery -- High Throughput Virtual Screening
Simon Cross,
Application Scientist, Tripos UK Ltd |
Wednesday, May 25
FELICIA CHEN-WU MEMORIAL
LECTURE
Chair: Cheng-Wen Wu
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11:10-12:00 |
MRI Visualization of Individual Immune Cells In Vivo: A New
Development in Cellular and Functional Imaging
Chien Ho,
Carnegie Mellon University, U.S.A. |
Chair: Cheng-Wen Wu
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13:30-14:10 |
PL1: Glycosphingolipid structure and membrane microdomains as
determinants of caveolar endocytosis
Richard E. Pagano, Mayo
Clinic and Foundation, U.S.A./UST Master Lecture |
INVITED LECTURE
Chair: Wen-guey Wu
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14:10-14:35 |
I01: Vaccinia virus entry and lipid rafts
Wen Chang,
Academia Sinica |
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14:35-15:10 |
I02: mitochondria as natural photosensitizers and its clinical
implication
Mei-Jie Jou, Chang Gung
University |
Section II Computational Biology
INVITED LECTURE
Chair:
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15:30-16:00 |
I03: TBA
Jenn-Kang Hwang, National Chiao Tung University |
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16:00-16:25
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I04: Prioritizing conserved hypothetical proteins for functional/structural
study
Chuan-Hsiung Chang, National Yang Ming
University |
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16:25-16:50 |
I05: Matrix Visualization and Information Mining for
Non-Continuous Biomedical Data Structure Using Generalized Association
Plots
Chun-houh Chen, Academia Sinica |
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16:50-17:15 |
I06:Molecular Dynamics Simulation of Folding of a Short Helical Peptide with
Two Disulfide Bonds
Ying-Chieh Sun, National Taiwan Normal
University |
Thursday, May 26
Section III
Chemical Biology in Drug Discovery
PLENARY LECTURE
Chair: Andrew
H.-J. Wang
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10:20-11:00 |
PL2: Post-translational Protein Glycosylation and Structure-based
Drug Discovery
Chi-Huey Wong, The Scripps Research Institute,
U.S.A. |
INVITED LECTURE
Chair: Po-Huang Liang
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11:00-11:30 |
I07: VX-680, a Novel Small Molecule Inhibitor of the Aurora kinases
Shin-San Su, Industrial Technology Research
Institute |
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11:30-12:00 |
I08: BPR1H036, a Novel Indole-based Pan-active PPAR Agonist: Design,
Structural Biology and In Vitro/In Vivo Biological Activities
Hsing-Pang Hsieh , National Health Research
Institutes |
Section IV Medical Imaging and Devices
PLENARY
LECTURE
Chair: Chung-Cheng Liu
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13:30-14:10 |
PL3: Controlling Cell as a Molecular System
Chih-Ming
Ho, University of California, Los Angeles,
U.S.A. |
INVITED LECTURE
Chair: Chung-Cheng Liu
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14:10-14:40 |
I09: Magnetic Resonance Microprobes for Molecular & Cellular
Studies
Long-Sheng Fan, National Tsing Hua
University |
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14:40-15:10 |
I10: Biomedical Visualization beyond the 3rd Dimension
Wei-Te Lin, Industrial Technology Research
Institute |
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19:00-19:40 |
Biophysics: Where Biology and Physics Rendezvous - Whither the
Need of an Integrated Graduate Training Program
P.C. Huang,
Johns Hopkins University |
Friday, May 27
Section V Frontier in Synchrotron
Radiation
PLENARY LECTURE
Chair:
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10:20-11:00 |
PL4: Structural biology on translation of genetic code using the third
generation synchrotron, SPring-8
Osamu Nureki, Tokyo
Institute of Technology, Japan |
INVITED LECTURE
Chair:
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11:00-11:30 |
I11:Structural and functional insight into sugar-nonspecific nucleases
in host defense
Hanna S.Yuan, Academia
Sinica |
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11:30-12:00 |
I12: Sulfur SAD Crystal Structure of CRISP from Naja atra Reveals
Ion Channel Blocking and Catalytic Folds with Heparin Binding Activity
Chun-Jung Chen, National Synchrotron Radiation
Research Center |
Section VI Biomolecular Interactions
PLENARY
LECTURE
Chair: Shwu-Huey Liaw
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13:30-14:10 |
PL5: Law and order in intrinsically disordered signaling
proteins
Kuan Wang, NIH,
U.S.A. |
INVITED LECTURE
Chair: Shwu-Huey Liaw
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14:10-14:40 |
I13: Structural Genomic and Functional Studies of Helicobacter
pylori by X-ray Crystallography
Yuh-Ju Sun, National Tsing
Hua University |
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14:40-15:10 |
I14: Identification of cellular proteins targeted by the activated
Notch1 receptor
Tien-Shun Yeh, Taipei Medical
University |
Section VII Protein Structure and Function
PLENARY
LECTURE
Chair: Deri- Lii Tzou
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15:10-16:10 |
PL6: Protein-Phosphoprotein Interactions - A New Frontier in Structural
Biology
Ming-Daw Tsai, Academia
Sinica |
INVITED LECTURE
Chair: Deri- Lii Tzou
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16:10-16:40 |
I15: Probing Protein Motion by NMR Relaxation
Shou-Lin Chang, National Tsing Hua
University |
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16:40-17:10 |
I16: Domain-swapping as a mechanism for regulating heparin binding
affinity and the function of the human hepatoma-derived growth factor
Tai-Huang Huang, Academia
Sinica |
Saturday, May 28
Tentative Program at NSRRC
Chair:
Chun-Jung Chen
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09:20-09:55 |
Structures of TopoIV-CTD, XpsE-NTD, and XveII - Examples of Se-MAD
Method
Nei-Li Chan, National Chung Hsing
University |
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09:55-10:30 |
Metalloproteins from Anaerobes for MAD Method
Ming-Yih Liu, NSRRC |
Chair: Nei-Li Chan
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10:50-11:25 |
Structure of an N-Acylamino Acid Racemase Homologue from Deinococcus
radiodurans- an Example of Hg-MAD Method
Wen-Ching
Wang, National Tsing Hua University |
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11:25-12:00 |
Crystal Structures and Electron Micrographs of Fungal Volcatoxin
A2-an Example of Br-MAD Method
Yen-Chywan Liaw, Academia
Sinica |
Chair: Yuch-Cheng Jean
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13:30-14:10 |
Introduction of High-throughput Crystallography at NSRRC
Yu-Shan Huang, NSRRC |
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14:10-14:40 |
Computing & Network Infrastructure at the Biological Crystallography
Beamlines at NSRRC
Chun-Hsiung Chao,
NSRRC |
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15:00-17:00
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NSRRC Tour
Yuch-Cheng Jean / Chun-Jung Chen / Tzu-Ling
Lee, NSRRC
Robot & Blu-ice Demonstration at BL13B
Yu-Shan Huang /
Cheng-Hung Chiang, NSRRC
Demonstration of Crystal Screening, Data Collection & Processing at
BL13B
Chun-Hsiung Chao / Chien-Chang Tseng,
NSRRC |
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