Content: Led by assistant research fellow Dr. Jr-Wen Shui at Institute of Biomedical Sciences, postdoc fellow Janaki Sudhakar and research associate Hsueh-Han Lu address those questions with animal disease models and publish in Nature Communications on Aug 27.2020. The group shows lack of glycosylation of lysosomal membrane protein or loss of glycan-binding galectin is pathologically associated with colitis and pancreatitis.

Article Link: https://doi.org/10.1038/s41467-020-18102-7

Glycosylation of Lysosomal Membrane Protein Plays a Key Role in Colitis and Pancreatitis