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New crystal structure sheds light on regulation of bacterial cell-wall remodeling |
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Using X-ray crystallography, the research team led by Dr. Chung-I Chang of the Institute of Biological Chemistry has revealed the three-dimensional structure of a protease system involved in cell-wall remodeling, which is tightly coupled to bacterial cell growth and division. The new structural study, published online on November 15 in Nature Communications, demonstrates how a lipoprotein adaptor and a protease form a three-sided docking cradle to mediate protein degradation in the outer membrane of Escherichia coli. For more information, please visit: http://www.ibc.sinica.edu.tw/Research_2017E5.asp
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