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A glycan that completes the journey of B cell |
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By altering the intracellular protein modification with sugar, Dr. Kuo-I Lin’s lab made B cells in mice turn lethargic when they reach mature age and mount the antibody responses. Lin’s group has a longtime interest in pursuing the ultimate question, “what makes a B Cell THE B cell?” They are surely one step closer to answer this question by putting the puzzle together in the latest Nature Communications article, “O-GlcNAcylation is required for B cell homeostasis and antibody responses”. Read the full article, please visit: http://www.genomics.sinica.edu.tw/index.php/en/news/latest-news
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