{"id":30499,"date":"2023-03-09T00:12:21","date_gmt":"2023-03-08T16:12:21","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=30499"},"modified":"2024-03-12T13:11:17","modified_gmt":"2024-03-12T05:11:17","slug":"%e6%96%b0%e9%80%b2%e4%ba%ba%e5%93%a1%e4%bb%8b%e7%b4%b9-%e7%94%9f%e7%89%a9%e9%86%ab%e5%ad%b8%e7%a7%91%e5%ad%b8%e7%a0%94%e7%a9%b6%e6%89%80%e9%84%ad%e6%8f%9a%e5%8a%a9%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/30499\/","title":{"rendered":"\u65b0\u9032\u4eba\u54e1\u4ecb\u7d39 \u2014\u2014 \u751f\u7269\u91ab\u5b78\u79d1\u5b78\u7814\u7a76\u6240\u912d\u63da\u52a9\u7814\u7a76\u54e1"},"content":{"rendered":"<p>Dr. Cheng Yang started his pre-doctoral training with Dr. Matthias von Herrath in La Jolla Institute and Dr. Mala Maini in University College London, where he gained extensive experience in the modulation of antigen-specific T cells in the context of type 1 diabetes, chronic LCMV and hepatitis B virus \uff08HBV\uff09 infection.<\/p>\n<p>During his doctoral and the first post-doctoral training at Singapore Immunology Network of A*STAR with Dr. Evan Newell, his research was focused on deep-profiling human virus-specific T cells in chronic HBV infection and HBV-associated liver disease and cancer using highly multiplexed combinatorial peptide-MHC tetramer staining, mass cytometry, single-cell multi-omics, and highdimensional analysis.<\/p>\n<p>Dr. Cheng discovered several novel T cell epitopes targeting HBV and HBV-reactive TCRs that can be used for immunotherapeutics. He and his research group found that HBV-specific memory T cell, or tumor-infiltrating tissue-resident memory HBV-specific T cell responses were linked to the patients\u2019 improved clinical outcomes.<\/p>\n<p>Dr. Cheng continued his human immunology research in Massachusetts General Hospital at Harvard Medical School as a Senior Research Scientist, exploring the tissue-resident memory human papillomavirus \uff08HPV\uff09-specific T cell responses in patients with HPV-associated diseases.<\/p>\n<p>Dr. Cheng Yang joined the Institute of Biomedical Sciences as an Assistant Research Fellow in January, 2023.<\/p>\n<p><strong>x \u5feb\u554f\u5feb\u7b54 x<\/strong><br \/>\nQ. \u60a8\u89ba\u5f97\u300c\u505a\u7814\u7a76\u300d\u6700\u96e3\u7684\u90e8\u5206\u662f\uff1f<br \/>\nA.<br \/>\n1.Perseverance.<br \/>\n2.Dealing with politics.<br \/>\n3.Fighting for resources that you cannot control.<\/p>\n<p>Q. \u9664\u4e86\u505a\u7814\u7a76\u4ee5\u5916\u7684\u8208\u8da3\uff1f<br \/>\nA. Scuba diving, surfing, climbing, ski \uff0f snowboarding, music, or just chilling on the beach.<\/p>\n<p>Q. \u5b78\u8853\u8def\u4e0a\u5f71\u97ff\u81ea\u5df1\u6700\u6df1\u7684\u4e00\u53e5\u8a71\u6216\u662f\u4e00\u6bb5\u6545\u4e8b\uff1f<br \/>\nA.\u201cMy time is over and now is your time. Let&#8217;s together make HBV the disease of past\u201d-Dr. Francis V. Chisari, the pioneer of HBV research. Retirement speech in September 2014 International HBV Meeting at UCLA.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-1024x615.jpg\" alt=\"\u65b0\u9032\u4eba\u54e1\u4ecb\u7d39 \u2014\u2014 \u751f\u7269\u91ab\u5b78\u79d1\u5b78\u7814\u7a76\u6240\u912d\u63da\u52a9\u7814\u7a76\u54e1\" width=\"1024\" height=\"615\" class=\"aligncenter size-large wp-image-30500\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-1024x615.jpg 1024w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-300x180.jpg 300w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-768x461.jpg 768w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-1080x649.jpg 1080w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-1280x768.jpg 1280w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-627x376.jpg 627w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2-440x264.jpg 440w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/03\/web-1785_4-2.jpg 1395w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Cheng Yang started his pre-doctoral training with D [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":30500,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[1706],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/30499"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=30499"}],"version-history":[{"count":1,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/30499\/revisions"}],"predecessor-version":[{"id":34345,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/30499\/revisions\/34345"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/30500"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=30499"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=30499"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=30499"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}