{"id":27208,"date":"2022-04-21T00:19:10","date_gmt":"2022-04-20T16:19:10","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=27208"},"modified":"2022-04-21T01:28:52","modified_gmt":"2022-04-20T17:28:52","slug":"%e3%80%90%e5%b0%88%e6%ac%84%e3%80%91%e6%a0%b8%e7%a3%81%e5%85%b1%e6%8c%af%e9%a0%bb%e8%ad%9c%e5%ad%b8-%e5%88%86%e5%ad%90%e7%9a%84%e6%94%be%e5%a4%a7%e9%8f%a1","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/27208\/","title":{"rendered":"\u3010\u5c08\u6b04\u3011\u6838\u78c1\u5171\u632f\u983b\u8b5c\u5b78\u2014\u2014\u5206\u5b50\u7684\u653e\u5927\u93e1"},"content":{"rendered":"

\u6838\u78c1\u5171\u632f\u8207\u8afe\u8c9d\u723e\u6842\u51a0<\/strong><\/p>\n

1952\u5e74\u8afe\u8c9d\u723e\u7269\u7406\u734e\u5206\u5225\u9812\u7d66\u5728\u7f8e\u570b\u7684\u5169\u4f4d\u7269\u7406\u5b78\u5bb6F Block\uff08Stanford\uff09\u548cEM Purcell \uff08Harvard\uff09\uff0c\u8868\u63da\u4ed6\u5011\u5728\u6838\u78c1\u5171\u632f\u7684\u7269\u7406\u73fe\u8c61\u91cd\u8981\u7684\u767c\u73fe\u3002\u4e4b\u5f8c\uff0c\u79d1\u5b78\u754c\u5728\u6838\u78c1\u5171\u632f\u7814\u7a76\u91cd\u5fc3\u5f9e\u7269\u7406\u79fb\u5230\u5316\u5b78\u53ca\u751f\u5316\u5b78\u9580\uff0c\u5ef6\u7e8c\u767c\u5149\u30021991\u5e74\u8afe\u8c9d\u723e\u5316\u5b78\u734e\u9812\u7d66RR Ernst\uff08Zurich\uff09 \u8868\u5f70\u4ed6\u5728\u958b\u767c\u9ad8\u89e3\u6790\u5ea6\u6838\u78c1\u5171\u632f\u65b9\u6cd5\u5b78\uff0c\u958b\u555f\u65b0\u91cc\u7a0b\u7891\u30022002\u5e74\u8afe\u8c9d\u723e\u5316\u5b78\u734e\u9812\u7d66K Wuthrich\uff08Zurich\uff09\u8868\u63da\u4ed6\u5728\u958b\u767c\u4e09\u7dad\u7a7a\u9593\u6838\u78c1\u5171\u632f\u5be6\u9a57\u65b9\u6cd5\u5b78\uff0c\u89e3\u6790\u751f\u7269\u5927\u5206\u5b50\u5373\u86cb\u767d\u8cea\u5728\u751f\u7406\u74b0\u5883\u4e0b\u4e4b\u7684\u5206\u5b50\u7d50\u69cb\u3002\u9694\u5e742003\u5e74\u8afe\u8c9d\u723e\u91ab\u5b78\u734e\u5206\u5225\u9812\u7d66PC Lauterbur\uff08Stony Brook\uff09\u548cP Mansfield\uff08Nottingham\uff09\uff0c\u8868\u63da\u4ed6\u5011\u9996\u5ea6\u5c07\u6838\u78c1\u5171\u632f\u983b\u8b5c\u5b78\u61c9\u7528\u5728\u4eba\u9ad4\u91ab\u5b78\u5f71\u50cf\u4e0a\uff0c\u56e0\u70ba\u4ed6\u5011\u7684\u7814\u7a76\u5de5\u4f5c\uff0c\u6211\u5011\u73fe\u5728\u91ab\u9662\u88e1\u624d\u6709\u78c1\u5171\u632f\u5f71\u50cf\u5100\uff0c\u4e5f\u5c31\u662fMRI\uff08Magnetic resonance imaging\uff09\u3002\u5341\u5e74\u5f8c\uff0c\u57282013\u5e74\u6cd5\u570b\u7684\u7406\u8ad6\u5316\u5b78\u5bb6M Karplus\uff08Strasbourg\uff09\u7372\u9812\u8afe\u8c9d\u723e\u5316\u5b78\u734e\uff0c\u8868\u5f70\u4ed6\u5728\u5efa\u7acb\u751f\u7269\u5de8\u5206\u5b50\u52d5\u614b\u6a21\u578b\u4e0a\u5353\u8d8a\u8ca2\u737b\u3002\u56e0\u70ba\u4ed6\u66fe\u7d93\u63d0\u51faKarplus\u65b9\u7a0b\u5f0f\uff0c\u900f\u904e\u6c2b\u5076\u5408\u5e38\u6578\u7684\u6e2c\u91cf\u53ef\u63a8\u7b97\u51fa\u4e8c\u9762\u89d2\uff08Dihedral angle\uff09\uff0c\u5c0d\u89e3\u6790\u5206\u5b50\u7d50\u69cb\u6709\u91cd\u8981\u50f9\u503c\u53ca\u610f\u7fa9\uff0c\u53ef\u4ee5\u7b97\u662f\u9593\u63a5\u56e0\u6838\u78c1\u5171\u632f\u5f97\u5230\u8afe\u8c9d\u723e\u734e\u3002\u56de\u9867\u6b77\u53f2\uff0c\u9bae\u5c11\u6709\u55ae\u4e00\u6280\u8853\uff0c\u53ef\u4ee5\u5f71\u97ff\u79d1\u5b78\u754c\u5982\u6b64\u6df1\u9060\uff0c\u6db5\u84cb\u7269\u7406\u3001\u5316\u5b78\u3001\u91ab\u5b78\u3001\u7406\u8ad6\u8a08\u7b97\u4e0d\u540c\u9818\u57df\uff0c\u7e3d\u6709\u4e03\u4f4d\u79d1\u5b78\u5bb6\u76f4\u63a5\u6216\u9593\u63a5\u56e0\u6b64\u6280\u8853\u8d0f\u5f97\u79d1\u5b78\u4e0a\u7684\u6b8a\u69ae\uff0c\u898b\u8868\u4e00\u3002\u6700\u65e9\u662f\u70ba\u7269\u7406\u5b78\u8005\u5bb6\u7684\u767c\u73fe\uff0c\u539f\u5b50\u6838\u6838\u78c1\u5834\u6709\u8b8a\u76f8\u4e92\u4f5c\u7528\u529b\uff0c\u904b\u7528\u4e00\u4e9b\u6280\u8853\u5982\u7121\u9650\u96fb\u8108\u885d\uff0c\u4ee5\u53ca\u5085\u5229\u8449\u8f49\u63db\uff0c\u53ef\u5c07\u8a0a\u865f\u8f49\u63db\u70ba\u983b\u8b5c\uff0c\u5206\u5b50\u4e4b\u983b\u8b5c\u53ef\u4ee5\u60f3\u50cf\u662f\u5982\u540c\u6307\u7d0b\uff0c\u4f5c\u70ba\u9451\u5b9a\u8fa8\u8b58\u4e4b\u7528\uff0c\u5316\u5b78\u5bb6\u767c\u73fe\u6b64\u4e00\u6280\u8853\u53ef\u4ee5\u904b\u7528\u5728\u5c0f\u5206\u5b50\u4ee5\u53ca\u751f\u5316\u5927\u5206\u5b50\u4e0a\uff0c\u9032\u884c\u91cf\u6e2c\uff0c\u800c\u4e14\u91cf\u6e2c\u7d50\u679c\u518d\u73fe\u6027\u9ad8\u4e14\u6e96\u78ba\u5ea6\u9ad8\uff0c\u4ea6\u5ee3\u6cdb\u61c9\u7528\u5728\u5176\u4ed6\u9818\u57df\u7684\u7814\u7a76\uff0c\u5305\u62ec\u751f\u5316\u3001\u5316\u5de5\u3001\u9ad8\u5206\u5b50\u6750\u6599\u53ca\u751f\u91ab\u7b49\u7b49\u3002<\/p>\n

\u672c\u6587\u5c07\u91dd\u5c0d\u6838\u78c1\u5171\u632f\u7684\u61c9\u7528\uff0c\u4f5c\u4e00\u6982\u62ec\u6027\u7c21\u8ff0\uff0c\u6709\u8208\u8da3\u8b80\u8005\u53ef\u4e0a\u7db2\u67e5\u8a62\u76f8\u95dc\u516c\u958b\u8cc7\u8a0a\u6216\u66f8\u7c4d\uff0c\u5be6\u969b\u6df1\u5165\u77ad\u89e3\u5167\u5bb9\u3002<\/p>\n

\"\"

\u8868\u4e00\u30011952-2013 \u6838\u78c1\u5171\u632f\u76f8\u95dc\u4e4b\u8afe\u8c9d\u723e\u734e\u6842\u51a0\u5f97\u4e3b<\/p><\/div>\n

\u6838\u78c1\u5171\u632f\u539f\u7406\u7c21\u8ff0<\/strong><\/p>\n

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\u78c1\u5171\u78c1\u5f71\u50cf MRI (Magnetic resonance imaging)<\/strong><\/p>\n

\u4e00\u822c\u4eba\u8a8d\u70ba\u6838\u78c1\u5171\u632f\u983b\u8b5c\u5b78\u662f\u4e00\u9580\u9ad8\u6df1\u5b78\u554f\uff0c\u65e5\u5e38\u751f\u6d3b\u4e0d\u6703\u7528\u5230\u63a5\u89f8\u5230\uff0c\u6bd4\u8f03\u5e38\u807d\u5230\u7684\u662f\u91ab\u9662\u5167\u78c1\u5171\u632f\u5f71\u50cf\uff0c\u4e5f\u5c31\u662fMRI\uff08Magnetic resonance imaging\uff09\u3002\u56e0MRI\u6280\u8853\u4e0d\u65b7\u9032\u6b65\uff0c\u8edf\u786c\u9ad4\u4e5f\u76f8\u7e7c\u66f4\u65b0\uff0c\u5546\u54c1\u5316\u7684\u78c1\u5171\u632f\u5f71\u50cf\u5100\u9678\u7e8c\u554f\u4e16\uff0c\u5982\u4eca\u5404\u500b\u5927\u91ab\u9662\u5927\u90fd\u5177\u5099\u4eba\u9ad4\u7528\u78c1\u5171\u632f\u5f71\u50cf\u5100\uff0c\u63d0\u4f9b\u91ab\u751f\u5011\u5c0d\u75c5\u60c5\u6216\u50b7\u5bb3\u5224\u8b80\u4e4b\u4f9d\u64da\u3002\u96d6\u7136\u91ab\u5b78\u78c1\u5171\u632f\u5f71\u50cf\u5100\u6aa2\u8996\u7528\u548c\u4e00\u822c\u7814\u7a76\u7528\u6838\u78c1\u5171\u632f\u983b\u8b5c\u7528\u9014\u8ff4\u7570\uff0c\u4e14\u5916\u89c0\u4e0a\u4e5f\u5927\u4e0d\u76f8\u540c\uff0c\u5982\u5716\u4e00\u6240\u793a\uff0c\u524d\u8005\u70ba\u6c34\u5e73\u8d85\u5c0e\u78c1\u9435\u4ee5\u914d\u5408\u4eba\u9ad4\u5e73\u79fb\u9032\u51fa\uff0c\u5f8c\u8005\u5247\u70ba\u76f4\u7acb\u578b\u8d85\u5c0e\u78c1\u9435\uff0c\u6a23\u54c1\u7531\u78c1\u9435\u4e0a\u65b9\u7f6e\u5165\uff0c\u4e8b\u5be6\u4e0a\uff0c\u5169\u8005\u7684\u57fa\u672c\u539f\u7406\u662f\u5b8c\u5168\u76f8\u540c\u7684\u3002\u78c1\u5171\u632f\u5f71\u50cf\u5100\u5075\u6e2c\u7684\u662f\u6c2b\u539f\u5b50\u8a0a\u865f\uff0c\u5373\u662f\u4eba\u9ad4\u6c34\u5206\u5b50\u7684\u8a0a\u865f\uff0c\u53ef\u900f\u904e\u5be6\u9a57\u8a2d\u5b9a\u89c0\u5bdf\u5230\u8166\u90e8\u6216\u5176\u4ed6\u90e8\u4f4d\u67d0\u4e00\u622a\u9762\u4e4b\u5f71\u50cf\uff0c\u76f8\u8f03\u65bc\u786c\u7d44\u7e54\u5982\u9aa8\u9abc\uff0c\u66f4\u65b9\u4fbf\u5075\u6e2c\u8edf\u7d44\u7e54\u542b\u6c34\u8f03\u9ad8\u5982\u8edf\u9aa8\u6216\u8166\u90e8\uff0c\u4e5f\u9069\u7528\u65bc\u4eba\u9ad4\u5176\u4ed6\u90e8\u4f4d\u3002\u518d\u8005\uff0c\u78c1\u5171\u632f\u5f71\u50cf\u7684\u53d6\u5f97\u7121\u4efb\u4f55\u653e\u5c04\u6027\u5371\u5bb3\u9867\u616e\uff0c\u552f\u5b89\u5168\u8003\u91cf\u4e0b\uff0c\u9032\u5165\u78c1\u5834\u56b4\u683c\u7981\u6b62\u651c\u5165\u4efb\u4f55\u91d1\u5c6c\u7269\u54c1\uff0c\u4ee5\u53ca\u91d1\u878d\u5361\u63d0\u6b3e\u5361\u7b49\uff0c\u53e6\u5916\u4e0b\u5217\u5e7e\u7a2e\u72c0\u6cc1\u9808\u8981\u7279\u5225\u6ce8\u610f;\u4f69\u5e36\u6709\u5fc3\u5f8b\u8abf\u6574\u5668\u4ee5\u53ca\u9ad4\u5167\u6709\u690d\u5165\u6027\u91d1\u5c6c\u7269\u8005\u4e0d\u5f97\u9760\u8fd1\u78c1\u5834\uff0c\u61f7\u5b55\u5a66\u5973\u4e0d\u5efa\u8b70\u53d6\u5f97\u5f37\u78c1\u5834\u5f71\u50cf\u3002<\/p>\n

\"\"

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