{"id":24023,"date":"2021-02-25T00:03:00","date_gmt":"2021-02-24T16:03:00","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=24023"},"modified":"2021-02-25T06:15:47","modified_gmt":"2021-02-24T22:15:47","slug":"%e8%9b%8b%e7%99%bd%e4%b8%8d%e7%a9%a9%e5%ae%9a%e4%b9%9f%e6%9c%83%e5%b0%8e%e8%87%b4%e6%99%ba%e8%83%bd%e9%9a%9c%e7%a4%99-%e5%a4%a7%e8%85%a6%e7%99%bc%e8%82%b2%e7%a0%94%e7%a9%b6%e6%96%b0%e7%aa%81%e7%a0%b4","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/24023\/","title":{"rendered":"\u86cb\u767d\u4e0d\u7a69\u5b9a\u4e5f\u6703\u5c0e\u81f4\u667a\u80fd\u969c\u7919 \u5927\u8166\u767c\u80b2\u7814\u7a76\u65b0\u7a81\u7834"},"content":{"rendered":"<div id=\"attachment_21652\" style=\"width: 1034px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-21652\" class=\"aligncenter size-large wp-image-24024\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2021\/02\/webimage-02-1024x615.jpg\" 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class=\"wp-caption-text\">\u672c\u9662\u751f\u7269\u5316\u5b78\u7814\u7a76\u6240\u9673\u745e\u83ef\u7279\u8058\u7814\u7a76\u54e1\uff08\u4e2d\uff09\u3001\u672c\u9662\u7d30\u80de\u8207\u751f\u7269\u5b78\u7814\u7a76\u6240\u5468\u7533\u5982\u526f\u7814\u7a76\u54e1(\u53f3)\u53ca\u672c\u9662\u751f\u7269\u5316\u5b78\u7814\u7a76\u6240\u6c5f\u5c1a\u6bb7\u535a\u58eb\u751f(\u5de6)<\/p><\/div>\n<p>\u667a\u80fd\u969c\u7919\u3001\u7672\u7647\u548c\u81ea\u9589\u75c7\u7b49\u60a3\u8005\u901a\u5e38\u9700\u8981\u7279\u6b8a\u6cbb\u7642\u3001\u6559\u80b2\u548c\u9577\u671f\u7167\u9867\uff0c\u5c0d\u5bb6\u5ead\u548c\u793e\u6703\u7d93\u6fdf\u90fd\u662f\u76f8\u7576\u5927\u7684\u8ca0\u64d4\u3002\u70ba\u4e86\u627e\u51fa\u5927\u8166\u767c\u80b2\u7570\u5e38\u7684\u6210\u56e0\uff0c\u904e\u5f80\u5b78\u754c\u7814\u7a76\u591a\u805a\u7126\u65bc\u57fa\u56e0\u8f49\u9304\u5c64\u9762\uff0c\u8f03\u5c11\u63a2\u8a0e\u86cb\u767d\u8cea\u4fee\u98fe\u7684\u91cd\u8981\u6027\u3002\u672c\u9662\u751f\u7269\u5316\u5b78\u7814\u7a76\u6240\u9673\u745e\u83ef\u7279\u8058\u7814\u7a76\u54e1\u548c\u672c\u9662\u7d30\u80de\u500b\u9ad4\u751f\u7269\u5b78\u7814\u7a76\u6240\u5468\u7533\u5982\u526f\u7814\u7a76\u54e1\u7684\u8de8\u9818\u57df\u7814\u7a76\u767c\u73fe\uff0c\u4eba\u9ad4\u4e2d\u7684\u86cb\u767dSOX11\u4e0d\u7a69\u5b9a\u6703\u5c0e\u81f4\u5927\u8166\u767c\u80b2\u7570\u5e38\uff1b\u7814\u7a76\u5718\u968a\u4e26\u627e\u5230\u53ef\u4ee5\u7a69\u5b9aSOX11\u7684\u6a5f\u5236\uff0c\u63d0\u51fa\u86cb\u767d\u8cea\u7a69\u5b9a\u5927\u8166\u767c\u80b2\u5bc6\u5207\u76f8\u95dc\u7684\u65b0\u89c0\u9ede\u3002\u7814\u7a76\u6210\u679c\u5df2\u65bc\u672c\uff082\uff09\u670812\u65e5\u767c\u8868\u65bc\u570b\u969b\u671f\u520a\u300a\u79d1\u5b78\u9032\u5c55\u300b(<em>Science Advances<\/em>)\u3002<\/p>\n<p>\u5927\u8166\u76ae\u5c64\u638c\u7ba1\u611f\u89ba\u3001\u904b\u52d5\u3001\u60c5\u7dd2\u3001\u8a8d\u77e5\u7b49\u591a\u9805\u91cd\u8981\u529f\u80fd\uff0c\u5176\u767c\u80b2\u6d89\u53ca\u8907\u96dc\u904e\u7a0b\uff0c\u5305\u62ec\u795e\u7d93\u751f\u6210\u3001\u795e\u7d93\u7d30\u80de\u79fb\u52d5\u3001\u7d44\u7e54\u5efa\u69cb\u53ca\u795e\u7d93\u7db2\u8def\u5f62\u6210\uff0c\u4efb\u4e00\u74b0\u7bc0\u5931\u8abf\u4fbf\u53ef\u80fd\u9020\u6210\u795e\u7d93\u6027\u75be\u75c5\u3002\u7814\u7a76\u5718\u968a\u767c\u73fe\uff0c\u907a\u50b3\u6027\u5927\u8166\u767c\u80b2\u7570\u5e38\u3001\u6709\u667a\u80fd\u969c\u7919\u8868\u578b\u7684\u75c5\u4eba\u66fe\u51fa\u73fe\u53bb\u6cdb\u7d20\uff08\u8a3b\u4e00\uff09\u86cb\u767dUSP11\u8b8a\u7570\u3002\u5be6\u9a57\u767c\u73fe\uff0c\u96d6\u7136\u5c0f\u9f20\u7f3a\u5c11USP11\u6642\uff0cSOX11\u4ecd\u53ef\u9032\u884c\u57fa\u56e0\u8f49\u9304\uff0c\u4f46\u56e0\u5176\u86cb\u767d\u4e0d\u7a69\u5b9a\uff0c\u9084\u662f\u6703\u5c0e\u81f4\u5927\u8166\u767c\u80b2\u7570\u5e38\u3002\u5728\u884c\u70ba\u5b78\u5206\u6790\uff08\u4f8b\u5982\uff1a\u5c0f\u9f20\u8d70\u8ff7\u5bae\uff09\u4e2d\uff0cUSP11\u7f3a\u5931\u4e4b\u6210\u9f20\u78ba\u5be6\u6709\u5b78\u7fd2\u8a18\u61b6\u548c\u793e\u4ea4\u60c5\u7dd2\u7b49\u591a\u91cd\u969c\u7919\u3002<\/p>\n<p>\u7814\u7a76\u5718\u968a\u767c\u73fe\u5728\u5927\u8166\u767c\u80b2\u904e\u7a0b\u4e2d\uff0cUSP11\u53ef\u6291\u5236SOX11\u86cb\u767d\u7684\u6cdb\u7d20\u5316\uff08\u8a3b\u4e8c\uff09\uff0c\u9032\u800c\u7a69\u5b9aSOX11\u7684\u8868\u73fe\u3002\u9019\u9805\u7a69\u5b9a\u6a5f\u5236\u4e0d\u4f46\u53c3\u8207\u4e86\u795e\u7d93\u751f\u6210\uff0c\u4e5f\u4f7f\u751f\u6210\u4e4b\u795e\u7d93\u79fb\u52d5\u5230\u6b63\u78ba\u4f4d\u7f6e\uff0c\u4ee5\u5efa\u69cb\u6b63\u5e38\u7684\u795e\u7d93\u7db2\u8def\u3002<\/p>\n<p>\u9673\u745e\u83ef\u7279\u8058\u7814\u7a76\u54e1\u8868\u793a\uff0c\u300c\u6b64\u7814\u7a76\u5c0d\u5927\u8166\u767c\u80b2\u7570\u5e38\u6240\u81f4\u75be\u75c5\u4e4b\u8a3a\u65b7\u548c\u6cbb\u7642\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8003\u65b9\u5411\uff0c\u672a\u4f86\u4e5f\u53ef\u671b\u7528\u4f86\u6aa2\u6e2c\u80ce\u5152\u7684\u5927\u8166\u767c\u80b2\u72c0\u6cc1\u3002\u300d\u6b64\u5916\uff0c\u7814\u7a76\u5718\u968a\u767c\u73fe\u8b8a\u7570\u5f8c\u7684USP11\u4e0d\u50c5\u6703\u55aa\u5931\u7a69\u5b9aSOX11\u7684\u529f\u80fd\uff0c\u4e5f\u7121\u6cd5\u652f\u6301\u5927\u8166\u6b63\u5e38\u767c\u80b2\uff0c\u66f4\u51f8\u986fUSP11\u7a69\u5b9aSOX11\u7684\u4f5c\u7528\u6a5f\u5236\u5c0d\u4eba\u985e\u5927\u8166\u767c\u80b2\u7684\u91cd\u8981\u6027\u3002<\/p>\n<p>\u672c\u8ad6\u6587\u7b2c\u4e00\u4f5c\u8005\u70ba\u672c\u9662\u751f\u5316\u6240\u535a\u58eb\u751f\u6c5f\u5c1a\u6bb7\u3002\u7814\u7a76\u5718\u968a\u5305\u62ec\u672c\u9662\u751f\u5316\u6240\u6797\u6dd1\u59a4\u7814\u7a76\u526f\u6280\u5e2b\uff0c\u672c\u9662\u7d30\u751f\u6240\u90ed\u7d18\u5fd7\u7814\u7a76\u54e1\uff0c\u4ee5\u53ca\u672c\u9662\u751f\u7269\u91ab\u5b78\u79d1\u5b78\u7814\u7a76\u6240\u9ec3\u6021\u8431\u7814\u7a76\u54e1\u3002\u7814\u7a76\u7d93\u8cbb\u7531\u4e2d\u592e\u7814\u7a76\u9662\u53ca\u79d1\u6280\u90e8\u5171\u540c\u652f\u6301\u3002<\/p>\n<p>\u8ad6\u6587\u5168\u6587\u9023\u7d50: <a href=\"https:\/advances.sciencemag.org\/content\/7\/7\/eabc6093\">https:\/advances.sciencemag.org\/content\/7\/7\/eabc6093<\/a><\/p>\n<hr 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[&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":24024,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[4],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/24023"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=24023"}],"version-history":[{"count":1,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/24023\/revisions"}],"predecessor-version":[{"id":24083,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/24023\/revisions\/24083"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/24024"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=24023"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=24023"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=24023"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}