{"id":22482,"date":"2020-07-30T00:03:39","date_gmt":"2020-07-29T16:03:39","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=22482"},"modified":"2020-12-23T14:19:13","modified_gmt":"2020-12-23T06:19:13","slug":"%e6%8a%97%e7%96%ab%e7%a0%94%e7%a9%b6%e3%80%8b%e6%8a%93%e5%be%97%e4%bd%8f%e7%97%85%e6%af%92%ef%bc%81%e4%b8%ad%e7%a0%94%e9%99%a2%e7%99%bc%e7%8f%be%e7%99%bd%e6%89%81%e8%b1%86%e8%90%83%e5%8f%96%e8%9b%8b","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/22482\/","title":{"rendered":"\u6297\u75ab\u7814\u7a76\u300b\u6293\u5f97\u4f4f\u75c5\u6bd2\uff01\u4e2d\u7814\u9662\u767c\u73fe\u767d\u6241\u8c46\u8403\u53d6\u86cb\u767d\u6709\u6548\u963b\u65b7\u65b0\u51a0\u75c5\u6bd2\u5165\u4fb5"},"content":{"rendered":"<p>\u672c\u9662\u57fa\u56e0\u9ad4\u7814\u7a76\u4e2d\u5fc3\u99ac\u5fb9\u7814\u7a76\u54e1\u53ca\u8a79\u5bb6\u742e\u7814\u7a76\u6280\u5e2b\u5408\u4f5c\uff0c\u8b49\u5be6\u5f9e\u767d\u6241\u8c46\u8403\u53d6\u51fa\u7684\u86cb\u767d\u8ceaFRIL\u53ef\u6293\u4f4f\u65b0\u51a0\u75c5\u6bd2\u8868\u9762\u7684\u91a3\u5206\u5b50\uff0c\u9032\u800c\u6291\u5236\u75c5\u6bd2\u611f\u67d3\u3001\u963b\u65b7\u5176\u50b3\u64ad\uff0c\u63d0\u4f9b\u65b0\u7684\u6297\u75ab\u7814\u767c\u65b9\u5411\u3002\u8a72\u7814\u7a76\u8ad6\u6587\u5df2\u65bc\u672c\uff087\uff09\u670824\u65e5\u520a\u767b\u65bc\u300a\u7d30\u80de\u5831\u544a\u300b\uff08<em>Cell Reports<\/em>\uff09\u3002<\/p>\n<p>\u8a79\u5bb6\u742e\u9577\u5e74\u5728\u4e2d\u8349\u85e5\u88e1\u627e\u5c0b\u50b3\u67d3\u75c5\u7684\u79d1\u5b78\u89e3\u65b9\uff0c\u7d93\u904e\u5be6\u9a57\u767c\u73fe\uff0c\u300a\u672c\u8349\u7db1\u76ee\u300b\u63d0\u904e\u7684\u300c\u767d\u6241\u8c46\u300d\u53ef\u6709\u6548\u6291\u5236\u6d41\u611f\u75c5\u6bd2\uff0c\u5176\u6548\u679c\u9060\u8d85\u904e\u5176\u4ed6\u56db\u767e\u591a\u7a2e\u4e2d\u85e5\uff0c\u66f4\u8207\u5e38\u898b\u7684\u897f\u85e5\u76f8\u7576\u3002\u99ac\u5fb9\u9577\u671f\u7814\u7a76\u5168\u6548\u6d41\u611f\u75ab\u82d7\uff0c\u4ed6\u8207\u8a79\u5bb6\u742e\u81ea2016\u5e74\u8d77\u4fbf\u8457\u624b\u7814\u7a76\u767d\u6241\u8c46\u6291\u5236\u6d41\u611f\u75c5\u6bd2\u7684\u539f\u56e0\uff0c\u4e26\u767c\u73fe\u95dc\u9375\u5c31\u662f\u2500\u2500\u86cb\u767d\u8ceaFRIL\u3002<\/p>\n<p>\u5f9e\u767d\u6241\u8c46\u8403\u53d6\u51fa\u7684FRIL\uff0c\u5176\u7d50\u69cb\u5982\u540c\u4e00\u9846\u6975\u5c0f\u578b\u7684\u6d88\u6ce2\u584a\uff08\u7d047\u5948\u7c73\u7acb\u65b9\uff09\uff0c\u6709\u56db\u500b\u5b8c\u5168\u4e00\u6a23\u3001\u5411\u5916\u7a81\u51fa\u7684\u7aef\u9ede\uff0c\u9019\u4e9b\u7aef\u9ede\u6703\u8207\u91a3\u5206\u5b50\u7522\u751f\u7d50\u5408\u4f5c\u7528\uff0c\u56e0\u6b64\uff0c\u4e00\u500bFRIL\u53ef\u540c\u6642\u6293\u4f4f\u5728\u5176\u5468\u570d\u7684\u591a\u500b\u91a3\u5206\u5b50\u3002\u7531\u65bc\u51a0\u72c0\u75c5\u6bd2\u8868\u9762\u7684\u68d8\u86cb\u767d\uff08Spike Protein\uff09\u8207\u6d41\u611f\u75c5\u6bd2\u8868\u9762\u4e00\u6a23\uff0c\u7686\u5e03\u6eff\u4e86\u91a3\u5206\u5b50\uff0c\u7814\u7a76\u5718\u968a\u5728\u4eca\uff082020\uff09\u5e74\u75ab\u60c5\u7206\u767c\u5f8c\uff0c\u4fbf\u7acb\u5373\u8457\u624b\u5c07\u6d41\u611f\u7814\u7a76\u5ef6\u7e8c\u81f3\u65b0\u51a0\u75c5\u6bd2\u7684\u6e2c\u8a66\u3002<\/p>\n<p>\u5728\u5148\u524d\u7684\u6d41\u611f\u5be6\u9a57\u4e2d\uff0c\u5718\u968a\u767c\u73fe\uff0c\u5728\u666e\u901a\u7684\u7d30\u80de\u5167\uff0c\u6d41\u611f\u75c5\u6bd2\u53ef\u9577\u9a45\u76f4\u5165\u5230\u7d30\u80de\u6838\u5167\uff0c\u9020\u6210\u611f\u67d3\uff0c\u4e26\u5728\u6578\u5c0f\u6642\u5f8c\u5c0e\u81f4\u7d30\u80de\u58de\u6b7b\u3002\u4f46\u5728\u52a0\u5165FRIL\u7684\u7d30\u80de\u4e2d\uff0c\u7d30\u80de\u6838\u5982\u540c\u591a\u4e86\u91d1\u9418\u7f69\u9435\u5e03\u886b\uff0c\u6d41\u611f\u75c5\u6bd2\u7121\u6cd5\u9032\u5165\uff0c\u611f\u67d3\u7387\u5927\u5e45\u4e0b\u964d\u81f310%\u4ee5\u4e0b\u3002\u5728\u65b0\u51a0\u75c5\u6bd2\u7684\u7d30\u80de\u5be6\u9a57\u4e2d\uff0c\u5718\u968a\u4e5f\u767c\u73fe\uff0c\u65b0\u51a0\u75c5\u6bd2\u7121\u6cd5\u9032\u5165\u7d93FRIL\u8655\u7406\u7684\u7d30\u80de\u7684\u7d30\u80de\u819c\uff0c\u6709\u6548\u6291\u5236\u611f\u67d3\u81f35%\u4ee5\u4e0b\u3002<\/p>\n<p>\u91dd\u5c0d\u6d41\u611f\uff0c\u7814\u7a76\u4eba\u54e1\u5df2\u9032\u4e00\u6b65\u505a\u904e\u5c0f\u9f20\u5be6\u9a57\u3002\u7d50\u679c\u986f\u793a\uff0c\u5728\u81f4\u6b7b\u5291\u91cf\u7684H1N1\u6d41\u611f\u75c5\u6bd2\u611f\u67d3\u4e4b\u4e0b\uff0c\u5f9e\u9f3b\u8154\u5674\u5165FRIL\uff083mg\/kg\uff09\u7684\u5c0f\u9f20\u4e2d\uff0c\u67097\u6210\u5b89\u7136\u7121\u6059\uff0c\u800c\u6c92\u6709FRIL\u4fdd\u8b77\u7684\u5c0f\u9f20\uff0c\u5247\u57288\u5929\u5167\u5168\u90e8\u6b7b\u4ea1\u3002\u4e0d\u50c5\u5982\u6b64\uff0c\u5718\u968a\u8fd1\u4e00\u6b65\u5c07FRIL\u8207\u76ee\u524d\u5c0d\u591a\u7a2e\u6d41\u611f\u6709\u6548\u7684\u5ee3\u6548\u6297\u9ad4FI6\u6bd4\u8f03\uff0c\u767c\u73fe\u572811\u7a2e\u6d41\u611f\u75c5\u6bd2\u682a\u4e2d\uff0cFRIL\u7684\u6291\u5236\u80fd\u529b\u6db5\u84cb\u6bd4FI6\u66f4\u591a\u7a2e\u7684\u6d41\u611f\uff0c\u5176\u6548\u529b\u4e5f\u66f4\u5f37\u3002<\/p>\n<p>\u4eca\u5e744\u6708\uff0c\u7814\u7a76\u5718\u968a\u5728\u53d6\u5f97\u81fa\u7063\u5927\u5b78\/\u75be\u7ba1\u7f72\u63d0\u4f9b\u7684\u75c5\u6bd2\u682a\u5f8c\uff08hCoV-19\/Taiwan\/NTU04\/2020\uff09\uff0c\u4fbf\u958b\u59cb\u6e2c\u8a66FRIL\u5c0d\u65b0\u51a0\u75c5\u6bd2\u7684\u6291\u5236\u80fd\u529b\u3002\u7d93\u5be6\u9a57\u767c\u73fe\uff0c\u53ea\u8981\u6975\u5c11\u91cf\u7684FRIL\uff0c\u5c31\u53ef\u4ee5\u6291\u5236SARS-CoV-2 \u611f\u67d3\u7d30\u80de\uff0c\u751a\u81f3\u5728\u611f\u67d3\u4ee5\u5f8c\u624d\u7d66\u4e88FRIL\u90fd\u6709\u986f\u8457\u7684\u6548\u679c\u3002\u7576\u75c5\u6bd2\u611f\u67d3\u7d30\u80de\u7684\u904e\u7a0b\u4e2d\u52a0\u5165FRIL\uff0cFRIL\u5e7e\u4e4e\u662f\u5168\u65b9\u4f4d\u7684\u6293\u4f4f\u56db\u5468\u7684\u68d8\u86cb\u767d\uff0c\u4f7f\u75c5\u6bd2\u56e0\u6b64\u52d5\u5f48\u4e0d\u5f97\u800c\u7121\u6cd5\u9032\u884c\u653b\u64ca\u3001\u8907\u88fd\u3002<\/p>\n<p>\u99ac\u5fb9\u8868\u793a\uff0c\u76ee\u524d\u7684\u6210\u679c\u4ecd\u5c6c\u57fa\u790e\u7814\u7a76\uff0c\u8981\u9032\u4e00\u6b65\u5c07\u7814\u7a76\u8f49\u5316\u6210\u6cbb\u7642\u6216\u9810\u9632\u7684\u91ab\u85e5\u7528\u54c1\uff0c\u9084\u6709\u5f88\u9577\u7684\u4e00\u6bb5\u8def\u3002\u4e0d\u904e\uff0c\u767d\u6241\u8c46\u4e0d\u50c5\u662f\u300a\u672c\u8349\u7db1\u76ee\u300b\u88e1\u6240\u8a18\u8f09\u7684\u8349\u85e5\uff0c\u5176\u5be6\u4e5f\u662f\u4e16\u754c\u4e0a\u8a31\u591a\u5730\u65b9\uff08\u5982\u5370\u5ea6\u3001\u6771\u5357\u4e9e\uff09\u7684\u65e5\u5e38\u98df\u7269\uff0c\u4ee3\u8868\u4eba\u985e\u98df\u7528\u767d\u6241\u8c46\u7684\u6b77\u53f2\u4e0a\u5343\u5e74\uff0c\u5b89\u5168\u3001\u53ef\u9760\u5ea6\u9ad8\u3002<\/p>\n<p>\u7814\u7a76\u8ad6\u6587 \u201cA Carbohydrate-binding protein from the edible Lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2\u201d\uff0c\u7b2c\u4e00\u4f5c\u8005\u70ba\u4e2d\u7814\u9662\u8207\u967d\u660e\u5927\u5b78\u5fae\u514d\u6240\u5408\u4f5c\u5b78\u7a0b\u535a\u58eb\u751f\u5289\u4f51\u6c11\uff0c\u5176\u4ed6\u4f5c\u8005\u5305\u542b\u590f\u79be\u5fb7\uff0c\u9673\u66c9\u854a\uff0c\u9673\u4ead\u6a3a\uff0c\u5ed6\u570b\u7fd4\uff0c\u7f85\u5a55\u73b2\uff0c\u5433\u9038\u6c11\uff0c\u4f55\u5b5f\u6a35\uff0c\u5433\u5b97\u76ca\uff0c\u7fc1\u555f\u60e0\uff0c\u8a79\u5bb6\u742e\u53ca\u99ac\u5fb9\u3002<\/p>\n<p>\u8ad6\u6587\u5168\u6587\u8a73\u898b\uff1a<a href=\"https:\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(20)31001-9\">https:\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(20)31001-9<\/a><\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_21652\" style=\"width: 379px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-21652\" class=\"aligncenter size-full wp-image-22483\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2020\/07\/1-2-1.jpg\" alt=\"\" width=\"369\" height=\"222\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2020\/07\/1-2-1.jpg 369w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2020\/07\/1-2-1-300x180.jpg 300w\" sizes=\"(max-width: 369px) 100vw, 369px\" \/><p id=\"caption-attachment-21652\" class=\"wp-caption-text\">\u57161\uff1a\u767d\u6241\u8c46<\/p><\/div>\n<div id=\"attachment_21652\" style=\"width: 620px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-21652\" class=\"aligncenter size-full wp-image-22484\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2020\/07\/1-2-2.png\" alt=\"\" width=\"610\" height=\"576\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2020\/07\/1-2-2.png 610w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2020\/07\/1-2-2-300x283.png 300w\" sizes=\"(max-width: 610px) 100vw, 610px\" \/><p id=\"caption-attachment-21652\" class=\"wp-caption-text\">\u57162\uff1aFRIL-3D\u7d50\u69cb\u793a\u610f\u5716<\/p><\/div>\n<p style=\"text-align: right;\">\uff08\u57fa\u56e0\u9ad4\u7814\u7a76\u4e2d\u5fc3\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u9662\u57fa\u56e0\u9ad4\u7814\u7a76\u4e2d\u5fc3\u99ac\u5fb9\u7814\u7a76\u54e1\u53ca\u8a79\u5bb6\u742e\u7814\u7a76\u6280\u5e2b\u5408\u4f5c\uff0c\u8b49\u5be6\u5f9e\u767d\u6241\u8c46\u8403\u53d6\u51fa\u7684\u86cb\u767d\u8ceaFRIL\u53ef\u6293\u4f4f\u65b0\u51a0\u75c5\u6bd2\u8868\u9762\u7684\u91a3\u5206\u5b50 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":22561,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[4],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/22482"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=22482"}],"version-history":[{"count":1,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/22482\/revisions"}],"predecessor-version":[{"id":22560,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/22482\/revisions\/22560"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/22561"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=22482"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=22482"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=22482"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}