{"id":20598,"date":"2019-11-28T08:00:36","date_gmt":"2019-11-28T00:00:36","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=20598"},"modified":"2021-08-04T09:02:15","modified_gmt":"2021-08-04T01:02:15","slug":"20191128f04","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/20598\/","title":{"rendered":"\u5927\u6578\u64da\u770b\u51fa\u7aef\u502a  \u57fa\u56e0\u7a81\u8b8a\u7684\u8c6c\u968a\u53cb\u795e\u6551\u63f4"},"content":{"rendered":"<p>DNA\u662f\u7531\u56db\u7a2e\u6838\u82f7\u9178A\u3001C\u3001G\u3001T\u6240\u7d44\u6210\uff0c\u9019\u56db\u500b\u300c\u5bc6\u78bc\u300d\u7684\u6392\u5217\u9806\u5e8f\u4e5f\u860a\u85cf\u907a\u50b3\u7684\u8a0a\u606f\u3002\u9019\u4e9b\u8a0a\u606f\u9700\u5148\u8f49\u9304\u6210RNA\uff0c\u518d\u7de8\u8f2f\u8f49\u8b6f\u6210\u86cb\u767d\u8cea\uff0c\u624d\u80fd\u904b\u4f5c\u751f\u547d\u6a5f\u5236\u3002\u904e\u53bb\u76f8\u95dc\u7814\u7a76\u5728\u8a0e\u8ad6\u57fa\u56e0\u7a81\u8b8a\u7684\u81f4\u75c5\u6027\u6642\uff0c\u672a\u66fe\u8003\u616e\u904eRNA\u7de8\u8f2f\u6a5f\u5236\u7684\u5f71\u97ff\u3002<\/p>\n<p>\u672c\u9662\u57fa\u56e0\u9ad4\u7814\u7a76\u4e2d\u5fc3\u838a\u6a39\u8ac4\u7814\u7a76\u54e1\u5718\u968a\uff0c\u5c07\u751f\u7269\u8cc7\u8a0a\u7d50\u5408\u5927\u6578\u64da\u5206\u6790\uff0c\u63a2\u8a0e\u300cA-to-G RNA\u7de8\u8f2f\uff08RNA editing\uff09\u6a5f\u5236\u300d\u8207\u57fa\u56e0\u7a81\u8b8a\u7684\u95dc\u4fc2\uff0c\u70ba\u75c5\u7406\u57fa\u56e0\u9ad4\u5b78\uff08pathogenomics\uff09\u63d0\u4f9b\u4e00\u500b\u65b0\u7684\u601d\u8003\u89d2\u5ea6\uff1a\u5728\u5224\u65b7\u57fa\u56e0\u7a81\u8b8a\u7684\u5371\u5bb3\u6027\u6642\uff0c\u9664\u4e86\u770bDNA\u5e8f\u5217\uff0c\u4e5f\u61c9\u8003\u91cfRNA\u8f49\u9304\u8cc7\u6599\uff0c\u624d\u80fd\u66f4\u7cbe\u78ba\u5730\u8a55\u4f30\u3002\u6b64\u7814\u7a76\u5df2\u65bc\u4eca\uff082019\uff09\u5e749\u6708\u767c\u8868\u65bc\u300a\u57fa\u56e0\u9ad4\u7814\u7a76\u300b\uff08<em>Genome Research<\/em>\uff09\u3002<\/p>\n<div id=\"attachment_20581\" style=\"width: 936px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20581\" class=\"wp-image-20581 size-full\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/20191128_1-1-2.jpg\" alt=\"\" width=\"926\" height=\"694\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/20191128_1-1-2.jpg 926w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/20191128_1-1-2-300x225.jpg 300w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/20191128_1-1-2-768x576.jpg 768w\" sizes=\"(max-width: 926px) 100vw, 926px\" \/><p id=\"caption-attachment-20581\" class=\"wp-caption-text\">\u838a\u6a39\u8ac4\u7814\u7a76\u5718\u968a\uff08\u4e2d\u70ba\u838a\u6a39\u8ac4\uff0c\u53f3\u4e8c\u70ba\u8ad6\u6587\u7b2c\u4e00\u4f5c\u8005\u9ea5\u5fb7\u502b\uff09<\/p><\/div>\n<p>\u838a\u6a39\u8ac4\u8868\u793a\uff0cA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u7684\u6b63\u5e38\u8207\u5426\uff0c\u548c\u81ea\u9589\u75c7\u3001\u7672\u7647\u53ca\u963f\u8332\u6d77\u9ed8\u75c7\u7b49\u8907\u96dc\u7684\u795e\u7d93\u75be\u75c5\u5bc6\u5207\u76f8\u95dc\uff0c\u6b64\u7814\u7a76\u7d50\u679c\u5c07\u6709\u52a9\u65bc\u77ad\u89e3\u76f8\u95dc\u75be\u75c5\uff0c\u53ef\u671b\u6e1b\u5c11\u63a2\u8a0e\u57fa\u56e0\u7a81\u8b8a\u6642\u5c0d\u5176\u81f4\u75c5\u53ca\u5371\u5bb3\u7a0b\u5ea6\u7684\u8aa4\u5224\uff0c\u540c\u6642\u4e5f\u89e3\u91cb\u4e86\u75c5\u7406\u57fa\u56e0\u9ad4\u5b78\u7684\u4e00\u5927\u8b0e\u984c\uff1a\u70ba\u4f55\u67d0\u4e9b\u6709\u5bb3\u7a81\u8b8a\u80fd\u5728\u6f14\u5316\u4e2d\u4fdd\u5b58\u81f3\u4eca\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u300cRNA\u7de8\u8f2f\u6a5f\u5236\u300d \u662f\u8c6c\u968a\u53cb\u9084\u662f\u795e\u6551\u63f4\uff1f<\/strong><\/p>\n<p>\u57fa\u56e0\u7a81\u8b8a\u5373\u662f\u57fa\u56e0\u4e2d\u7684A\u3001C\u3001G\u3001T\u6392\u5217\u767c\u751f\u8b8a\u7570\u3002\u5982\u679c\u67d0\u500b\u4f4d\u7f6e\u672c\u61c9\u662f\u300cA\u300d\uff0c\u537b\u8b8a\u6210\u300cG\u300d\uff0c\u5373\u662f\u767c\u751f\u300cA\/G\u9ede\u7a81\u8b8a\u300d\u3002\u5982\u679c\u7a81\u8b8a\u767c\u751f\u5728\u91cd\u8981\u7684\u57fa\u56e0\u4f4d\u7f6e\uff0c\u5f71\u97ff\u5230\u5f8c\u7e8c\u7522\u751f\u7684\u86cb\u767d\u8cea\u529f\u80fd\uff0c\u4fbf\u6703\u5c0d\u751f\u547d\u9ad4\u9020\u6210\u5371\u5bb3\u3002<br \/>\nA-to-G RNA\u7de8\u8f2f\u6a5f\u5236 \u53ef\u4ee5\u5728DNA<span style=\"color: #000080;\"><sup>[1]<\/sup><\/span>\u8f49\u9304\u6210RNA\u6642\uff0c\u5c07RNA\u4e2d\u7684\u300cA\u300d\uff0c\u8f49\u63db\u6210\u300cG\u300d\u3002\u838a\u6a39\u8ac4\u56e0\u6b64\u597d\u5947\uff0c\u9019\u5957\u6a5f\u5236\u5c0dDNA\u4e0a\u7684A\/G\u57fa\u56e0\u7a81\u8b8a\u800c\u8a00\uff0c\u7a76\u7adf\u662f\u63d0\u6cb9\u6551\u706b\u7684\u300c\u8c6c\u968a\u53cb\u300d\uff0c\u9084\u662f\u96ea\u4e2d\u9001\u70ad\u7684\u300c\u795e\u6551\u63f4\u300d\uff1f\u4ed6\u5927\u81bd\u5047\u8a2d\uff1aA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\uff0c\u53ef\u4f7f\u67d0\u4e9bA\/G\u9ede\u7a81\u8b8a\u7684\u5371\u5bb3\u6027\u4e0b\u964d\u3002<\/p>\n<p>\u7814\u7a76\u5718\u968a\u9996\u5148\u6574\u5408\u4e86447\u4f4d\u4e0d\u540c\u4eba\u985e\u500b\u9ad4\u7684DNA\u53caRNA\u5e8f\u5217\u8cc7\u6599\uff0c\u9032\u884c\u5927\u6578\u64da\u7d71\u8a08\u8207\u6f14\u5316\u5206\u6790\uff0c\u4e26\u8a55\u4f30A\/G\u9ede\u7a81\u8b8a\u7684\u5371\u5bb3\u7a0b\u5ea6\u3001\u5728\u7fa4\u9ad4\u4e2d\u7684\u767c\u751f\u983b\u7387\uff0c\u53ca\u5176\u8207A-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u9593\u7684\u95dc\u4fc2\u3002\u63a5\u8457\uff0c\u518d\u6df1\u5165\u5206\u6790\u300c\u5343\u4eba\u57fa\u56e0\u9ad4\u8a08\u5283\u300d\uff081000 Genomes Project\uff09\u8490\u96c6\u5230\u903e2000\u4eba\u7684DNA\u5e8f\u5217\u8cc7\u6599\u5f8c\u8b49\u5be6\uff1aA-to-G RNA\u7de8\u8f2f\u4e8b\u4ef6\u78ba\u5be6\u548cA\u3001G\u5169\u7a2e\u6838\u82f7\u9178\u7684\u767c\u751f\u7387\u6709\u95dc\uff0c\u5c24\u5176\u7576A\/G\u9ede\u7a81\u8b8a\u6240\u9020\u6210\u7684\u5371\u5bb3\u8d8a\u5927\uff0c\u76f8\u95dc\u6027\u5c31\u8d8a\u5927\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>RNA\u7de8\u8f2f\u6a5f\u5236\u8207\u57fa\u56e0\u7a81\u8b8a\u7684\u95dc\u4fc2<\/strong><\/p>\n<p>\u5206\u6790\u7d50\u679c\u986f\u793a\uff0c\u57fa\u56e0\u7a81\u8b8a\u5371\u5bb3\u7684\u7a0b\u5ea6\u8ddfA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u5bc6\u5207\u76f8\u95dc\uff1a<\/p>\n<p>\u4e00\u3001 \u7576A\u7a81\u8b8a\u6210G\uff08A\u2192G\uff09\u6709\u5bb3\u6642\uff0cA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u4fbf\u6703\u53d7\u5230\u6291\u5236\uff1b\u800c\u7576G\u2192A\u7a81\u8b8a\u6709\u5bb3\u6642\uff0c\u8a72\u6a5f\u5236\u7684\u767c\u751f\u7387\u5247\u660e\u986f\u63d0\u9ad8\u3002<\/p>\n<p>\u4e8c\u3001 \u7576A\u2192G\u7a81\u8b8a\u8d8a\u6709\u5bb3\uff0c\u8a72\u7a81\u8b8a\u7684\u6240\u4f54\u6bd4\u7387\u5c31\u8d8a\u4f4e\uff1b\u800c\u7576G\u2192A\u7a81\u8b8a\u8d8a\u6709\u5bb3\uff0cG\u2192A\u6240\u4f54\u6bd4\u7387\u5247\u8d8a\u9ad8\uff08\u5716A\uff09\u3002<\/p>\n<p>\u4e09\u3001 \u7d93\u7531A-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u7684\u8fa8\u8b58\u5e8f\u5217 \uff08ADAR motif\uff09<span style=\"color: #000080;\"><sup>[2]<\/sup><\/span>\u5206\u6790\u986f\u793a\uff0c\u82e5G\u2192A\u7a81\u8b8a\u767c\u751f\u5728DNA\u7684\u4f4d\u9ede\u8d8a\u91cd\u8981\uff0c\u4ea6\u5373\u8a72\u7a81\u8b8a\u7684\u5371\u5bb3\u7a0b\u5ea6\u8d8a\u5927\uff0c\u5247\u8a72\u9ede\u767c\u751fA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u7684\u53ef\u80fd\u6027\u4e5f\u6703\u8d8a\u9ad8\uff08\u5716B\uff09\u3002<\/p>\n<div id=\"attachment_20651\" style=\"width: 409px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20651\" class=\"wp-image-20651 size-full\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-1.png\" alt=\"\" width=\"399\" height=\"298\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-1.png 399w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-1-300x224.png 300w\" sizes=\"(max-width: 399px) 100vw, 399px\" \/><p id=\"caption-attachment-20651\" class=\"wp-caption-text\">\u5716A\uff1a\u7576\u932f\u7fa9\u7a81\u8b8a\u8d8a\u662f\u6709\u5bb3\u6642\uff0cA\u2192G\u7a81\u8b8a\u6240\u4f54\u6bd4\u7387\u8d8a\u4f4e\uff0c\u800cG\u2192A\u7a81\u8b8a\u6240\u4f54\u6bd4\u7387\u5247\u8d8a\u9ad8<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_20652\" style=\"width: 332px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20652\" class=\"wp-image-20652 size-full\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-2.png\" alt=\"\" width=\"322\" height=\"352\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-2.png 322w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-2-274x300.png 274w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><p id=\"caption-attachment-20652\" class=\"wp-caption-text\">\u5716B\uff1aA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u7684\u8fa8\u8b58\u5e8f\u5217\uff08ADAR motif\uff09\u51fa\u73fe\u7387\u548c\u7a81\u8b8a\u5371\u5bb3\u7a0b\u5ea6\u7684\u6bd4\u8f03\u3002<\/p><\/div>\n<p>&nbsp;<\/p>\n<p>\u5f9e\u4ee5\u4e0a\u7d50\u679c\u53ef\u63a8\u6e2c\uff0c\u4eba\u9ad4\u6703\u900f\u904e\u8abf\u63a7A-to-G RNA\u7de8\u8f2f\u6a5f\u5236\uff0c\u4f86\u5e73\u8861\u57fa\u56e0\u7a81\u8b8a\u9020\u6210\u7684\u5371\u5bb3\u3002\u7576A\u2192G\u7a81\u8b8a\u5c0d\u751f\u547d\u6709\u5bb3\u6642\uff0c\u751f\u547d\u9ad4\u5c31\u964d\u4f4eA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u767c\u751f\u7387\uff0c\u4ee5\u6e1b\u5c11A\u8b8a\u6210G\uff1b\u76f8\u53cd\u5730\uff0c\u5982\u679c\u9020\u6210\u5371\u5bb3\u7684\u662fG\u2192A\u7a81\u8b8a\uff0cA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u5c31\u53ef\u80fd\u6703\u300c\u795e\u6551\u63f4\u300d\uff0c\u628a\u539f\u672c\u6709\u5bb3\u7684A\uff0c\u56de\u5fa9\u70baG\u3002<\/p>\n<p>\u838a\u6a39\u8ac4\u8868\u793a\uff0c\u672c\u6b21\u7814\u7a76\u6210\u679c\u6709\u8cf4\u5927\u6578\u64da\u3001\u751f\u7269\u8cc7\u8a0a\u8207\u5805\u5be6\u7684\u6f14\u7b97\u908f\u8f2f\u63a8\u5c0e\uff08\u5716C\uff09\u3002\u5728\u4eba\u985eDNA\u5e8f\u5217\u4e0a30\u5104\u500b\u9e7c\u57fa\u88ab\u89e3\u78bc\u4e4b\u5f8c\uff0c\u79d1\u5b78\u5bb6\u5f97\u4ee5\u85c9\u6b64\u63a2\u7d22\u4eba\u9ad4\u5167\u5404\u7a2e\u751f\u547d\u6a5f\u5236\u7684\u8b8a\u5316\u8207DNA\u4e4b\u9593\u7684\u95dc\u4fc2\u3002\u8fd1\u5e74\u4f86\u500b\u4eba\u5316\u5168\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u5206\u6790\u8d8a\u4f86\u8d8a\u666e\u904d\u3002\u9019\u4e9b\u5927\u91cf\u4e14\u591a\u6a23\u7684\u5b9a\u5e8f\u8cc7\u6599\uff0c\u82e5\u7d93\u904e\u5927\u6578\u64da\u7684\u8655\u7406\uff0c\u53ef\u4ee5\u5354\u52a9\u91ab\u7642\u8a3a\u65b7\u7684\u5224\u8b80\uff0c\u56e0\u6b64\uff0c\u751f\u7269\u8cc7\u8a0a\u5206\u6790\u6108\u5f62\u91cd\u8981\u3002<\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_20650\" style=\"width: 601px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20650\" class=\"wp-image-20650 size-full\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-3.png\" alt=\"\" width=\"591\" height=\"340\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-3.png 591w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/11\/4-3-300x173.png 300w\" sizes=\"(max-width: 591px) 100vw, 591px\" \/><p id=\"caption-attachment-20650\" class=\"wp-caption-text\">\u672c\u7814\u7a76\u6240\u9700\u7684\u77e5\u8b58\u80cc\u666f\u96f7\u9054\u5716\u3002\u76ee\u524d\u8a72\u7814\u7a76\u5718\u968a\u4e2d\u6709\u4e00\u534a\u662f\u300c\u7d14\u7406\u5de5\u300d\u80cc\u666f\uff0c\u53e6\u4e00\u534a\u662f\u300c\u7d14\u5206\u5b50\u751f\u7269\u300d\u80cc\u666f\uff0c\u4e00\u500b\u7406\u60f3\u7684\u751f\u7269\u8cc7\u8a0a\u5718\u968a\u6975\u9700\u8981\u4e0a\u8ff0\u5169\u7a2e\u80cc\u666f\u7684\u540c\u4ec1\u7dca\u5bc6\u5408\u4f5c\u3002\u6b61\u8fce\u5177\u5099\u4e0a\u8ff0\u4efb\u4e00\u80cc\u666f\u7684\u540c\u5b78\u52a0\u5165\u5d84\u65b0\u7684\u751f\u7269\u8cc7\u8a0a\u4e16\u754c\u3002<\/p><\/div>\n<p>&nbsp;<\/p>\n<p>\u672c\u8ad6\u6587\u7b2c\u4e00\u4f5c\u8005\u70ba\u57fa\u56e0\u9ad4\u7814\u7a76\u4e2d\u5fc3\u9ea5\u5fb7\u502b\u535a\u58eb\u3002\u8ad6\u6587\u5168\u6587\u8a73\u898b\uff1a<a href=\"https:\/genome.cshlp.org\/content\/early\/2019\/09\/12\/gr.246033.118.full.pdf+html\">https:\/genome.cshlp.org\/content\/early\/2019\/09\/12\/gr.246033.118.full.pdf+html<\/a><\/p>\n<p style=\"text-align: right;\">\uff08\u57fa\u56e0\u9ad4\u7814\u7a76\u4e2d\u5fc3\uff09<\/p>\n<hr \/>\n<p><sup><span style=\"color: #000080;\">[1]<\/span>\u00a0<\/sup>A-to-G RNA\u7de8\u8f2f\u4e8b\u4ef6\u5e38\u898b\u65bc\u591a\u7d30\u80de\u751f\u7269\uff0c\u5176\u529f\u80fd\u9020\u6210\u7684\u5f71\u97ff\u662f\u597d\u662f\u58de\u5728\u5b78\u754c\u4ecd\u6709\u722d\u8b70\u3002\u5b83\u4e00\u65b9\u9762\u6709\u6a5f\u6703\u589e\u52a0\u5e8f\u5217\u591a\u6a23\u6027\uff0c\u8b93\u86cb\u767d\u8cea\u7522\u751f\u65b0\u529f\u80fd\uff0c\u53e6\u4e00\u65b9\u9762\u4e5f\u53ef\u80fd\u4f7f\u86cb\u767d\u8cea\u529f\u80fd\u53d7\u640d\u800c\u5c0e\u81f4\u300c\u932f\u7fa9\u7a81\u8b8a\u300d\u3002\u8a31\u591a\u7814\u7a76\u986f\u793a\uff0c\u9019\u500b\u6a5f\u5236\u7684\u5931\u8abf\u548c\u81ea\u9589\u75c7\u3001\u808c\u840e\u7e2e\u5074\u7d22\u786c\u5316\u75c7\u3001\u985b\u7647\u3001\u963f\u8332\u6d77\u9ed8\u75c7\u7b49\u795e\u7d93\u75be\u75c5\u6709\u95dc\u3002\u838a\u6a39\u8ac4\u5718\u968a\u9664\u4e86\u958b\u767c\u65b0\u7684A-to-G RNA\u7de8\u8f2f\u4e8b\u4ef6\u5c0b\u627e\u65b9\u6cd5\uff08ICARES\uff09\u4e4b\u5916\uff0c\u4e5f\u5c0dA-to-G RNA\u7de8\u8f2f\u4e8b\u4ef6\u5728\u4e0d\u540c\u591a\u7d30\u80de\u52d5\u7269\u9593\u505a\u4e86\u5ee3\u6cdb\u7684\u63a2\u8a0e\uff08\u8a73\u898b2018\u5e74\u767c\u8868\u5728<em>Genome Biology and Evolution<\/em>\u7684\u8ad6\u6587\uff1a<a href=\"https:\/academic.oup.com\/gbe\/article\/10\/2\/521\/4774976\">https:\/academic.oup.com\/gbe\/article\/10\/2\/521\/4774976<\/a>\uff09\u3002<\/p>\n<p><sup><span style=\"color: #000080;\">[2]<\/span>\u00a0A-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u662f\u900f\u904e\u300cADAR\u86cb\u767d\u8cea\u300d\u5f97\u4ee5\u904b\u4f5c\uff0c\u800c\u672c\u5206\u6790\u5373\u662f\u900f\u904eADAR motif\u4f86\u9810\u6e2cA-to-G RNA\u7de8\u8f2f\u6a5f\u5236\u662f\u5426\u767c\u751f\u3002<\/sup><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DNA\u662f\u7531\u56db\u7a2e\u6838\u82f7\u9178A\u3001C\u3001G\u3001T\u6240\u7d44\u6210\uff0c\u9019\u56db\u500b\u300c\u5bc6\u78bc\u300d\u7684\u6392\u5217\u9806\u5e8f\u4e5f\u860a\u85cf\u907a\u50b3\u7684\u8a0a\u606f\u3002\u9019\u4e9b\u8a0a\u606f\u9700\u5148\u8f49\u9304\u6210RNA\uff0c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":20580,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[4],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/20598"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=20598"}],"version-history":[{"count":2,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/20598\/revisions"}],"predecessor-version":[{"id":20649,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/20598\/revisions\/20649"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/20580"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=20598"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=20598"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=20598"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}