{"id":19902,"date":"2019-09-26T00:05:07","date_gmt":"2019-09-25T16:05:07","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=19902"},"modified":"2020-12-25T13:26:52","modified_gmt":"2020-12-25T05:26:52","slug":"%e7%82%ba%e4%bb%80%e9%ba%bc%e4%b8%8d%e9%96%8b%e8%8a%b1%ef%bc%9f%e6%9c%ac%e9%99%a2%e7%99%bc%e7%8f%be%e6%a4%8d%e7%89%a9%e6%96%b0%e5%9e%8b%e6%85%8b%e7%9a%84%e5%9f%ba%e5%9b%a0%e8%a1%a8%e7%8f%be%e8%aa%bf","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/19902\/","title":{"rendered":"\u70ba\u4ec0\u9ebc\u4e0d\u958b\u82b1\uff1f\u672c\u9662\u767c\u73fe\u690d\u7269\u65b0\u578b\u614b\u7684\u57fa\u56e0\u8868\u73fe\u8abf\u63a7\u6a5f\u5236"},"content":{"rendered":"<p>\u57fa\u56e0\u8868\u73fe\u51fa\u932f\u4e86\uff0c\u4e0d\u50c5\u6703\u5c0e\u81f4\u4eba\u985e\u8a31\u591a\u907a\u50b3\u6027\u75be\u75c5\uff0c\u4e5f\u6703\u9020\u6210\u690d\u7269\u751f\u9577\u9072\u7de9\u3001\u5ef6\u9072\u958b\u82b1\u7b49\u554f\u984c\u3002\u5f71\u97ff\u690d\u7269\u57fa\u56e0\u8868\u73fe\u7684\u91cd\u8981\u95dc\u9375\u4e4b\u4e00\uff0c\u6b63\u662f\u5b83\u91cd\u8981\u7684\u751f\u9577\u80fd\u6e90\u2500\u2500\u5149\u7dda\uff0c\u5176\u4e2d\u4e0d\u53ef\u6216\u7f3a\u7684\u8abf\u63a7\u56e0\u5b50\uff0c\u5247\u662f\u611f\u6e2c\u5149\u7dda\u7684\u300c\u5149\u654f\u7d20\u300d(phytochrome)\u3002<\/p>\n<p>\u672c\u9662\u690d\u7269\u66a8\u5fae\u751f\u7269\u5b78\u7814\u7a76\u6240<a href=\"https:\/ipmb.sinica.edu.tw\/ch\/ipmb_researchers#ipmb-22\">\u6d82\u4e16\u9686\u526f\u7814\u7a76\u54e1<\/a>\u767c\u73fe\uff0c\u690d\u7269\u5438\u6536\u5149\u4e4b\u5f8c\uff0c\u611f\u6e2c\u5149\u7dda\u7684\u300c\u5149\u654f\u7d20\u300d\u9032\u5165\u7d30\u80de\u6838\u8abf\u63a7\u57fa\u56e0\u8868\u73fe\u904e\u7a0b\u7684\u526a\u63a5\u6b65\u9a5f\uff0c\u555f\u52d5\u57fa\u56e0\u7522\u51fa\u5404\u5f0f\u86cb\u767d\u8cea\u7522\u7269\uff0c\u63a7\u5236\u690d\u7269\u751f\u9577\u767c\u80b2\uff0c\u6b64\u7814\u7a76\u6210\u679c\u5df2\u65bc\u4eca\uff08108\uff09\u5e748\u6708\u520a\u767b\u65bc\u300a\u690d\u7269\u7d30\u80de\u300b(<em>The Plant Cell<\/em>)\u3002<\/p>\n<p>\u5149\u7dda\u662f\u690d\u7269\u6700\u9700\u8981\u7684\u80fd\u91cf\u4f86\u6e90\u4e4b\u4e00\uff0c\u4e0d\u50c5\u662f\u5149\u5408\u4f5c\u7528\u7684\u57fa\u672c\u80fd\u6e90\uff0c\u4e5f\u662f\u690d\u7269\u751f\u9577\u767c\u80b2\u91cd\u8981\u7684\u8abf\u7bc0\u56e0\u5b50\uff0c\u5f71\u97ff\u5f9e\u840c\u82bd\u3001\u767c\u80b2\u3001\u958b\u82b1\u8207\u7d50\u679c\u7b49\u5404\u500b\u968e\u6bb5\u3002<\/p>\n<p><strong>\u5149\u654f\u7d20\u63a5\u6536\u5149\u7dda<\/strong> <strong>\u8abf\u63a7\u57fa\u56e0\u8868\u73fe<\/strong><\/p>\n<p>\u6d82\u4e16\u9686\u6307\u51fa\uff0c\u690d\u7269\u9ad4\u5167\u5b58\u5728\u5404\u7a2e\u5149\u63a5\u53d7\u5668\uff0c\u611f\u6e2c\u4e0d\u540c\u6ce2\u9577\u7684\u5149\u7dda\u4ee5\u8abf\u7bc0\u751f\u9577\u3002\u672c\u6b21\u7814\u7a76\u7684\u7d05\u5149\u63a5\u53d7\u5668\u86cb\u767d\u300c\u5149\u654f\u7d20\u300d\uff0c\u904e\u53bb\u5df2\u88ab\u8b49\u5be6\u6703\u5f71\u97ff\u690d\u7269\u57fa\u56e0\u526a\u63a5\u3002\u7814\u7a76\u5718\u968a\u89c0\u5bdf\u5c0f\u7acb\u7897\u861a (<em>Physcomitrella patens<\/em>)\u63a5\u6536\u7d05\u5149\u7167\u5c04\u5f8c\uff0c\u5149\u654f\u7d20\u8abf\u63a7\u690d\u7269\u57fa\u56e0\u8868\u73fe\u88e1\u7684\u66ff\u4ee3\u6027\u526a\u63a5(Alternative splicing<a href=\"#_ftn1\" name=\"_ftnref1\">[1]<\/a>)\uff0c\u548c\u524d\u8a0a\u606fRNA(precursor mRNA<a href=\"#_ftn2\" name=\"_ftnref2\"><sup>[2]<\/sup><\/a>\uff09\u3001\u4ee5\u53ca\u8ca0\u8cac\u57f7\u884c\u526a\u63a5\u7684\u8907\u5408\u9ad4\u7b49\u86cb\u767d\u8cea\u9032\u884c\u4e00\u9023\u4e32\u7684\u4ea4\u4e92\u4f5c\u7528\uff0c\u8b93\u4e00\u500b\u57fa\u56e0\u7522\u51fa\u591a\u7a2e\u4e0d\u540c\u7684\u86cb\u767d\u8cea\uff0c\u78ba\u4fdd\u690d\u7269\u80fd\u6b63\u5e38\u767c\u80b2\u3002<\/p>\n<p>\u4e0a\u8ff0\u968e\u6bb5\u70ba\u57fa\u56e0\u8868\u73fe\u88e1\u7684\u66ff\u4ee3\u6027\u526a\u63a5\uff0c\u85c9\u7531\u4e0d\u540c\u7684\u524d\u8a0a\u606fRNA\u526a\u63a5\u65b9\u5f0f\uff0c\u53ef\u4f7f\u4e00\u6bb5\u57fa\u56e0\u7522\u751f\u591a\u7a2e\u4e0d\u540c\u985e\u578b\u7684mRNA\uff0c\u9032\u800c\u5f71\u97ff\u86cb\u767d\u8cea\u7522\u7269\u7684\u7d44\u6210\uff0c\u8f49\u8b6f\u51fa\u591a\u7a2e\u4e0d\u540c\u86cb\u767d\u8cea\uff0c\u986f\u8457\u5f71\u97ff\u690d\u7269\u7684\u751f\u9577\u767c\u80b2\u3001\u751f\u7406\u8abf\u63a7\u3002<\/p>\n<p>\u6d82\u4e16\u9686\u7814\u7a76\u5718\u968a\u4e5f\u767c\u73fe\uff0c\u5c0f\u7acb\u7897\u861a\u82e5\u7f3a\u5c11\u5149\u654f\u7d20\uff0c\u4ee5\u53ca\u6703\u548c\u5149\u654f\u7d20\u9032\u884c\u4ea4\u4e92\u4f5c\u7528\u7684\u86cb\u767d\u8cea\uff0c\u5c07\u5c0e\u81f4\u66ff\u4ee3\u6027\u526a\u63a5\u7f3a\u5931\u53ca\u767c\u80b2\u5f62\u614b\u8b8a\u7570\uff0c\u6b64\u4e5f\u8b49\u5be6\u9019\u4e9b\u86cb\u767d\u8cea\u85c9\u7531\u57f7\u884c\u66ff\u4ee3\u6027\u526a\u63a5\uff0c\u78ba\u4fdd\u5149\u7167\u4e0b\u7684\u5c0f\u7acb\u7897\u861a\u53ef\u4ee5\u6b63\u5e38\u767c\u80b2\u3002<\/p>\n<p>\u5728\u52d5\u7269\u7cfb\u7d71\u7814\u7a76\u4e2d\uff0c\u66ff\u4ee3\u6027\u526a\u63a5\u5df2\u88ab\u8b49\u5be6\u548c\u591a\u7a2e\u75be\u75c5\u76f8\u95dc\u3002\u4e0d\u7cbe\u78ba\u7684\u524d\u8a0a\u606fRNA\u526a\u63a5\u53ef\u80fd\u6703\u7522\u51fa\u932f\u8aa4\u7684\u86cb\u767d\u8cea\u7522\u7269\uff0c\u5c0e\u81f4\u751f\u7406\u75c5\u8b8a\u3002\u8a31\u591a\u7814\u7a76\u4ea6\u986f\u793a\uff0c\u66ff\u4ee3\u6027\u526a\u63a5\u7684\u7f3a\u5931\u6703\u5c0e\u81f4\u591a\u7a2e\u690d\u7269\u751f\u9577\u554f\u984c\uff0c\u4f8b\u5982\uff1a\u751f\u9577\u9072\u7de9\u3001\u5ef6\u9072\u958b\u82b1\u7b49\u3002\u7136\u800c\uff0c\u76ee\u524d\u79d1\u5b78\u5bb6\u5c0d\u65bc\u690d\u7269\u5982\u4f55\u9032\u884c\u66ff\u4ee3\u6027\u526a\u63a5\u7684\u77ad\u89e3\u4ecd\u76f8\u7576\u7f3a\u4e4f\u3002<\/p>\n<p>\u6d82\u4e16\u9686\u8868\u793a\uff0c\u82e5\u80fd\u6df1\u5165\u7406\u89e3\u66ff\u4ee3\u6027\u526a\u63a5\u5982\u4f55\u8abf\u63a7\u958b\u82b1\uff0c\u4fbf\u6709\u6a5f\u6703\u85c9\u6b64\u63a7\u5236\u690d\u7269\u958b\u82b1\u6642\u9593\uff0c\u8abf\u7bc0\u6216\u5ef6\u9577\u82b1\u5349\u4f5c\u7269\u7684\u7522\u5b63\uff0c\u76ee\u524d\u7814\u7a76\u5718\u968a\u6b63\u671d\u6b64\u65b9\u5411\u52aa\u529b\u3002<\/p>\n<p>\u672c\u8ad6\u6587\u7531\u4e2d\u7814\u9662\u53ca\u79d1\u6280\u90e8\u652f\u6301\uff0c\u7b2c\u4e00\u4f5c\u8005\u70ba\u672c\u9662\u570b\u969b\u7814\u7a76\u751f\u5206\u5b50\u8207\u751f\u7269\u8fb2\u696d\u79d1\u5b78\u5b78\u7a0b\u535a\u58eb\u73ed\u5b78\u751f\u65bd\u73cf\u5982\uff0c\u6d82\u4e16\u9686\u70ba\u6307\u5c0e\u6559\u6388\uff0c\u5171\u540c\u4f5c\u8005\u5305\u62ec\u9673\u858c\u96ef\u3001\u8b1d\u6b23\u5b87\u3001\u8cf4\u96cd\u83ef\u3001\u90b1\u82b3\u8abc\u3001\u9673\u6631\u84c9\u3002<\/p>\n<p>\u8ad6\u6587\u6a19\u984c\uff1aHeterogeneous Nuclear Ribonucleoprotein H1 Coordinates with Phytochrome and the U1 snRNP Complex to Regulate Alternative Splicing in Physcomitrella patens<\/p>\n<p>\u8ad6\u6587\u9023\u7d50\uff1a<a href=\"http:\/www.plantcell.org\/content\/early\/2019\/08\/13\/tpc.19.00314?rss=1\">http:\/www.plantcell.org\/content\/early\/2019\/08\/13\/tpc.19.00314?rss=1<\/a><\/p>\n<div id=\"attachment_19903\" style=\"width: 710px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-19903\" class=\"size-full wp-image-19903\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/09\/1-3-1.jpg\" alt=\"\" width=\"700\" height=\"350\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/09\/1-3-1.jpg 700w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/09\/1-3-1-300x150.jpg 300w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/09\/1-3-1-574x287.jpg 574w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><p id=\"caption-attachment-19903\" class=\"wp-caption-text\">\u300c\u5149\u654f\u7d20\u300d\u63a5\u6536\u5149\u7dda\u5f8c\uff08\u53f3\u5716\uff09\uff0c\u9032\u5165\u7d30\u80de\u6838\u8abf\u63a7\u66ff\u4ee3\u6027\u526a\u63a5\uff0c\u4f7f\u4e00\u6bb5\u57fa\u56e0\u7522\u751f\u4e0d\u540c\u578b\u5f0f\u7684\u86cb\u767d\u8cea\u3002\u76f8\u8f03\u65bc\u5de6\u5716\u7121\u5149\u6e90\uff0c\u4e26\u4ee5\u526a\u5200\u6578\u91cf\u4e0d\u540c\u5448\u73fe\u4e4b\uff0c\u4ee3\u8868\u690d\u7269\u5728\u6709\/\u7121\u5149\u6e90\u4e0b\uff0c\u9032\u884c\u4e0d\u540c\u7684\u526a\u63a5\u65b9\u5f0f\u3002<\/p><\/div>\n<p style=\"text-align: right;\">\uff08\u690d\u7269\u66a8\u5fae\u751f\u7269\u5b78\u7814\u7a76\u6240\uff09<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"#_ftnref1\" name=\"_ftn1\">[1]<\/a> \u66ff\u4ee3\u6027\u526a\u63a5\uff1a\u524d\u8a0a\u606fRNA\u7d93\u7531\u6578\u7a2e\u4e0d\u540c\u7684\u526a\u63a5\u65b9\u5f0f\uff0c\u7522\u751f\u4e0d\u540c\u7d44\u614b\uff0f\u578b\u5f0f\u7684mRNA\uff0c\u4f7f\u4e00\u6bb5\u57fa\u56e0\u5728\u4e0d\u540c\u7684\u7d44\u7e54\u6216\u767c\u80b2\u904e\u7a0b\u4e2d\u80fd\u7d93\u904e\u8f49\u9304-\u526a\u63a5-\u8f49\u8b6f\u5f8c\u7522\u751f\u4e0d\u540c\u578b\u5f0f\u7684\u86cb\u767d\u8cea\uff0c\u9032\u800c\u64c1\u6709\u4e0d\u540c\u7684\u4f5c\u7528\uff0c\u6216\u662f\u7522\u751f\u51fa\u7a69\u5b9a\u6027\u5dee\u7684mRNA\u9054\u5230\u8abf\u63a7\u57fa\u56e0\u8868\u73fe\u7684\u76ee\u7684\u3002<\/p>\n<p><a href=\"#_ftnref2\" name=\"_ftn2\">[2]<\/a> \u524d\u8a0a\u606fRNA (precursor mRNA\uff09\uff1a\u7531DNA\u7d93\u7531\u8f49\u9304\u800c\u4f86\uff0c\u5e36\u8457\u76f8\u61c9\u7684\u907a\u50b3\u8a0a\u606f\uff0c\u5c1a\u9700\u7d93\u7531\u6578\u7a2e\u4e0d\u540c\u7684\u526a\u63a5\u65b9\u5f0f\uff0c\u4f7f\u5176\u6210\u70ba\u6210\u719f\u7684mRNA\u5f8c\uff0c\u65b9\u53ef\u9032\u884c\u8f49\u8b6f\u6210\u86cb\u767d\u8cea\u7684\u6b65\u9a5f\u3002<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u57fa\u56e0\u8868\u73fe\u51fa\u932f\u4e86\uff0c\u4e0d\u50c5\u6703\u5c0e\u81f4\u4eba\u985e\u8a31\u591a\u907a\u50b3\u6027\u75be\u75c5\uff0c\u4e5f\u6703\u9020\u6210\u690d\u7269\u751f\u9577\u9072\u7de9\u3001\u5ef6\u9072\u958b\u82b1\u7b49\u554f\u984c\u3002\u5f71\u97ff\u690d\u7269\u57fa\u56e0\u8868\u73fe\u7684\u91cd\u8981\u95dc\u9375 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":19903,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[4],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/19902"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=19902"}],"version-history":[{"count":1,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/19902\/revisions"}],"predecessor-version":[{"id":19904,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/19902\/revisions\/19904"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/19903"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=19902"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=19902"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=19902"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}