{"id":18220,"date":"2019-05-23T00:03:07","date_gmt":"2019-05-22T16:03:07","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=18220"},"modified":"2021-08-04T14:35:02","modified_gmt":"2021-08-04T06:35:02","slug":"%e5%a5%88%e7%b1%b3%e7%b4%9a%e7%9a%84%e6%a8%a1%e4%bb%bf%ef%bc%81%e5%86%a0%e7%8b%80%e7%97%85%e6%af%92%e7%96%ab%e8%8b%97%e5%8f%af%e6%9c%9b%e7%a0%b4%e8%a7%a3mers","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/18220\/","title":{"rendered":"\u5948\u7c73\u7d1a\u7684\u6a21\u4eff\uff01\u51a0\u72c0\u75c5\u6bd2\u75ab\u82d7\u53ef\u671b\u7834\u89e3MERS"},"content":{"rendered":"<p>\u4ee4\u5404\u570b\u805e\u4e4b\u8272\u8b8a\u3001\u6709\u300c\u65b0SARS\u300d\u4e4b\u7a31\u7684\u300c\u4e2d\u6771\u547c\u5438\u9053\u75c7\u5019\u7fa4\u300d\uff08Middle East Respiratory Syndrome, MERS\uff09\uff0c\u56e0\u5176\u75c5\u6bd2\u8b8a\u7570\u5feb\u901f\uff0c\u81f3\u4eca\u6c92\u6709\u4efb\u4f55\u6709\u6548\u7684\u75ab\u82d7\u6216\u85e5\u7269\u3002\u5982\u4eca\uff0c\u7d50\u5408\u5948\u7c73\u79d1\u6280\u53ca\u51a0\u72c0\u75c5\u6bd2\u7814\u7a76\uff0c\u53ef\u671b\u7372\u5f97\u89e3\u65b9\uff01<\/p>\n<p>\u672c\u9662\u751f\u7269\u91ab\u5b78\u79d1\u5b78\u7814\u7a76\u6240\u80e1\u54f2\u9298\u52a9\u7814\u7a76\u54e1\uff0c\u8207\u570b\u7acb\u81fa\u7063\u5927\u5b78\u7378\u91ab\u5b78\u7cfb\u9673\u6167\u6587\u526f\u6559\u6388\uff0c\u53ca\u7f8e\u570b\u5fb7\u5dde\u5dde\u7acb\u5927\u5b78\u7d44\u6210\u570b\u969b\u8de8\u9818\u57df\u5718\u968a\uff0c\u904b\u7528\u5c16\u7aef\u5948\u7c73\u79d1\u6280\uff0c\u6a21\u4eff\u51a0\u72c0\u75c5\u6bd2\u5916\u578b\uff0c\u7814\u767c\u51fa\u5275\u65b0\u6709\u6548\u7684\u300c\u51a0\u72c0\u75c5\u6bd2\u5948\u7c73\u75ab\u82d7\u300d\uff0c\u6709\u52a9\u65bc\u5c0d\u6297\u4e2d\u6771\u547c\u5438\u9053\u75c7\u5019\u7fa4\u3002\u7814\u7a76\u6210\u679c\u65bc\u8fd1\u65e5\u520a\u767b\u65bc<strong>\u300a\u5148\u9032\u529f\u80fd\u6750\u6599\u300b\uff08<\/strong><strong><em>Advanced Functional Materials<\/em><\/strong><strong>\uff09<\/strong>\u671f\u520a\uff0c\u8a72\u6280\u8853\u4e26\u5df2\u7533\u8acb\u591a\u570b\u5c08\u5229\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-18221\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2.jpg\" alt=\"\" width=\"836\" height=\"504\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2.jpg 836w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-300x181.jpg 300w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-768x463.jpg 768w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-440x264.jpg 440w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-836x504.jpg 840w\" sizes=\"(max-width: 836px) 100vw, 836px\" \/><\/p>\n<p>\u4e2d\u6771\u547c\u5438\u9053\u75c7\u5019\u7fa4\uff08MERS\uff09\u7531\u51a0\u72c0\u75c5\u6bd2\u5f15\u8d77\uff0c\u662f\u9ad8\u5371\u96aa\u6027\u7684\u4eba\u755c\u5171\u901a\u50b3\u67d3\u75c5\uff0c\u5176\u81f4\u6b7b\u7387\u5c07\u8fd1\u56db\u6210\uff0c\u65bc\u6b50\u3001\u7f8e\u3001\u4e9e\u3001\u975e\u6d32\u767c\u751f\u6578\u5343\u500b\u611f\u67d3\u75c5\u4f8b\u3002\u7531\u65bc\u76ee\u524d\u4e26\u7121\u4efb\u4f55\u75ab\u82d7\u6216\u85e5\u7269\uff0c\u4e16\u754c\u5404\u570b\u767c\u73fe\u75c5\u4f8b\u7686\u5f15\u8d77\u6050\u614c\uff0c\u4e16\u754c\u885b\u751f\u7d44\u7e54\uff08WHO\uff09\u66f4\u5c07\u5176\u5217\u70ba\u9996\u8981\u5c0d\u6297\u4e4b\u65b0\u8208\u611f\u67d3\u75c7\u4e4b\u4e00\u3002\u4e2d\u6771\u547c\u5438\u9053\u75c7\u5019\u7fa4\u75c5\u6bd2\uff08MERS-CoV\uff09\u8b8a\u7570\u5feb\u901f\uff0c\u6975\u9808\u7528\u5275\u65b0\u75ab\u82d7\u624d\u80fd\u5c0d\u4ed8\u3002<\/p>\n<p>\u80e1\u54f2\u9298\u70ba\u8584\u6bbc\u4e2d\u7a7a\u5948\u7c73\u7c92\u5b50\u7684\u767c\u660e\u8005\u3002\u4ed6\u8868\u793a\uff0c\u75ab\u82d7\u7684\u529f\u80fd\uff0c\u5c31\u662f\u8b93\u9ad4\u5167\u7684\u514d\u75ab\u7cfb\u7d71\u300c\u4ee5\u70ba\u300d\u8eab\u9ad4\u5df2\u88ab\u75c5\u6bd2\u4fb5\u7565\uff0c\u63d0\u524d\u7522\u751f\u514d\u75ab\u53cd\u61c9\uff0c\u9032\u800c\u62b5\u79a6\u771f\u6b63\u7684\u75c5\u6bd2\u3002\u56e0\u6b64\uff0c\u8a31\u591a\u75ab\u82d7\u4fbf\u6703\u7279\u5730\u6a21\u4eff\u75c5\u6bd2\u7684\u7279\u6027\u3002\u672c\u7814\u7a76\u767c\u660e\u7684\u5948\u7c73\u75ab\u82d7\uff0c\u4fbf\u662f\u6bd4\u7167\u75c5\u6bd2\uff0c\u5c07\u6297\u539f\u505a\u6210\u5948\u7c73\u5927\u5c0f\uff0c\u66f4\u6a21\u4eff\u51a0\u72c0\u75c5\u6bd2\u8868\u9762\u7684\u300c\u7687\u51a0\u6a23\u7a81\u8d77\u300d\uff0c\u5728\u8584\u6bbc\u5948\u7c73\u7c92\u5b50\u7684\u8868\u9762\uff0c\u8986\u4e0a\u300c\u86cb\u767d\u8cea\u51a0\u300d\uff0c\u9032\u800c\u8b93\u642d\u8f09\u65bc\u7c92\u5b50\u5167\u90e8\u7684\u5948\u7c73\u7d1a\u5f37\u6548\u4f50\u5291\uff0c\u5f97\u4ee5\u4e00\u8d77\u50b3\u905e\u4e88\u514d\u75ab\u7d30\u80de\uff0c\u523a\u6fc0\u514d\u75ab\u7cfb\u7d71\u7522\u751f\u6297\u9ad4\uff0c\u5927\u5e45\u63d0\u5347\u514d\u75ab\u529b\u3002<\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_18222\" style=\"width: 1389px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-18222\" class=\"wp-image-18222 size-full\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2.png\" alt=\"\" width=\"1379\" height=\"473\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2.png 1379w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-300x103.png 300w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-768x263.png 768w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-1024x351.png 1024w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2019\/05\/1-1-2-1080x370.png 1080w\" sizes=\"(max-width: 1379px) 100vw, 1379px\" \/><p id=\"caption-attachment-18222\" class=\"wp-caption-text\"><strong>\u5716\u8aaa\uff1a\u672c\u7814\u7a76\u767c\u660e\u7684\u5948\u7c73\u75ab\u82d7\uff0c\u4fbf\u662f\u6bd4\u7167\u75c5\u6bd2\uff0c\u5c07\u6297\u539f\u505a\u6210\u5948\u7c73\u5927\u5c0f\uff0c\u66f4\u6a21\u4eff\u51a0\u72c0\u75c5\u6bd2\u8868\u9762\u7684\u300c\u7687\u51a0\u6a23\u7a81\u8d77\u300d\uff0c\u5728\u8584\u6bbc\u5948\u7c73\u7c92\u5b50\u7684\u8868\u9762\uff0c\u8986\u4e0a\u300c\u86cb\u767d\u8cea\u51a0\u300d\uff0c\u9032\u800c\u8b93\u642d\u8f09\u65bc\u7c92\u5b50\u5167\u90e8\u7684\u5948\u7c73\u7d1a\u5f37\u6548\u4f50\u5291\uff0c\u5f97\u4ee5\u4e00\u8d77\u50b3\u905e\u4e88\u514d\u75ab\u7d30\u80de\uff0c\u523a\u6fc0\u514d\u75ab\u7cfb\u7d71\u7522\u751f\u6297\u9ad4\uff0c\u5927\u5e45\u63d0\u5347\u514d\u75ab\u529b\u3002<\/strong><\/p><\/div>\n<p>&nbsp;<\/p>\n<p>\u5c08\u9577\u70ba\u51a0\u72c0\u75c5\u6bd2\u7814\u7a76\u7684\u9673\u6167\u6587\u8868\u793a\uff0c\u5c07\u6b64\u5948\u7c73\u75ab\u82d7\u6ce8\u5165\u5c0f\u9f20\u4e26\u6df1\u5165\u5206\u6790\uff0c\u7d50\u679c\u986f\u793a\uff0c\u6b64\u5948\u7c73\u75ab\u82d7\u80fd\u6709\u6548\u88ab\u52d5\u7269\u9ad4\u5167\u7684\u514d\u75ab\u7cfb\u7d71\u8fa8\u8b58\uff0c\u8a98\u767c\u4eff\u771f\u514d\u75ab\u53cd\u61c9\uff0c\u4f7f\u8840\u6db2\u4e2d\u6709\u6548\u6297\u9ad4\u7dad\u6301\u9577\u9054300\u5929\u4ee5\u4e0a\uff0c\u540c\u6642\uff0c\u6b64\u75ab\u82d7\u4ea6\u5f37\u5316\u4e86\u9ad4\u5167\u7684T\u7d30\u80de\uff0c\u53ef\u6709\u6548\u6bd2\u6bba\u75c5\u6bd2\uff0c\u9054\u5230\u767e\u5206\u4e4b\u767e\u7684\u52d5\u7269\u5b58\u6d3b\u7387\uff01\u7814\u7a76\u5718\u968a\u4e5f\u5f37\u8abf\uff0c\u51a0\u72c0\u75c5\u6bd2\u5948\u7c73\u75ab\u82d7\u6b63\u6301\u7e8c\u8207\u570b\u969b\u5718\u968a\u5408\u4f5c\uff0c\u63a5\u4e0b\u4f86\uff0c\u5c07\u5728\u9748\u9577\u985e\u52d5\u7269\u8b49\u660e\u75ab\u82d7\u7684\u6548\u6027\u5f8c\uff0c\u9032\u5165\u81e8\u5e8a\u7814\u7a76\u3002\u800c\u81fa\u7063\u5718\u968a\u6b63\u7a4d\u6975\u5c07\u6b64\u5948\u7c73\u75ab\u82d7\u6cbf\u7528\u5728\u6d41\u611f\u75ab\u82d7\u3001\u8332\u5361\u75c5\u6bd2\u75ab\u82d7\uff0c\u4ee5\u53ca\u764c\u75c7\u75ab\u82d7\u7684\u7814\u767c\u3002<\/p>\n<p>\u672c\u8de8\u570b\u7814\u7a76\u5718\u968a\u7531\u80e1\u54f2\u9298\u3001\u9673\u6167\u6587\u53ca\u7f8e\u570b\u5fb7\u5dde\u5927\u5b78\u5fae\u751f\u7269\u66a8\u514d\u75ab\u6240Dr. Chien-Te Kent Tseng\u8cc7\u6df1\u6559\u6388\u5718\u968a\u7d44\u6210\u3002\u7814\u7a76\u5718\u968a\u6210\u54e1\u5305\u62ec\u6797\u5efa\u7def\u535a\u58eb\uff08\u7b2c\u4e00\u4f5c\u8005\uff09\u3001\u9ec3\u6e5e\u923a\u3001\u59da\u79c9\u745c\u3001\u6797\u69ae\u8fb0\u535a\u58eb\u3001\u5289\u7389\u6db5\u535a\u58eb\u3001\u9ec3\u67c4\u7ff0\u535a\u58eb\u7b49\u4eba\uff0c\u81fa\u7063\u5927\u5b78\u524d\u6559\u52d9\u9577\u838a\u69ae\u8f1d\u6559\u6388\u4ea6\u5171\u540c\u53c3\u8207\u3002\u6b64\u7814\u7a76\u7531\u300c\u570b\u7acb\u81fa\u7063\u5927\u5b78\u8207\u4e2d\u592e\u7814\u7a76\u9662\u5275\u65b0\u6027\u5408\u4f5c\u8a08\u756b\u300d\u53ca\u79d1\u6280\u90e8\u300c\u81fa\u7063\u91cd\u8981\u65b0\u8208\u611f\u67d3\u75c7\u7814\u7a76\u8a08\u756b\u300d\u652f\u6301\u7814\u767c\uff0c\u4e26\u8207\u7f8e\u570b\u5fb7\u5dde\u5927\u5b78\u91ab\u5b78\u5206\u90e8\u4e4b\u9ad8\u7b49\u751f\u7269\u5b89\u5168\u5be6\u9a57\u5ba4\u5408\u4f5c\uff0c\u5b8c\u6210\u5948\u7c73\u75ab\u82d7\u4e4b\u81e8\u5e8a\u524d\u6e2c\u8a66\u3002\u6b64\u767c\u660e\u4ea6\u66fe\u5165\u9078\u79d1\u6280\u90e8106\u5e74\u4e4b\u300c\u672a\u4f86\u79d1\u6280\u5c55\u300d\u5c55\u51fa\uff0c\u5177\u6709\u76f8\u7576\u9ad8\u7684\u5546\u54c1\u5316\u50f9\u503c\u3002<\/p>\n<p>\u7814\u7a76\u6210\u679c\u8acb\u8a73\u95b1\u8ad6\u6587\u5168\u6587\uff1a\u201cViromimetic STING Agonist-Loaded Hollow Polymeric Nanoparticles for Safe and Effective Vaccination against Middle East Respiratory Syndrome Coronavirus.\u201d <strong><em>Advanced Functional Materials<\/em><\/strong> doi:10.1002\/adfm.201807616 (2019)\u3002<\/p>\n<p>\uff08\u751f\u91ab\u6240\u3001\u79d8\u66f8\u8655\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4ee4\u5404\u570b\u805e\u4e4b\u8272\u8b8a\u3001\u6709\u300c\u65b0SARS\u300d\u4e4b\u7a31\u7684\u300c\u4e2d\u6771\u547c\u5438\u9053\u75c7\u5019\u7fa4\u300d\uff08Middle East Respiratory S [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":18221,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[4],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/18220"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=18220"}],"version-history":[{"count":2,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/18220\/revisions"}],"predecessor-version":[{"id":25114,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/18220\/revisions\/25114"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/18221"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=18220"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=18220"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=18220"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}