{"id":17751,"date":"2019-04-25T00:00:16","date_gmt":"2019-04-24T16:00:16","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=17751"},"modified":"2021-04-27T14:58:55","modified_gmt":"2021-04-27T06:58:55","slug":"%e4%ba%ba%e9%ab%94%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e6%98%af%e5%9c%a8%e7%b7%a8%e4%bb%80%e9%ba%bc%ef%bc%9f%e4%ba%94%e5%88%86%e9%90%98%e6%90%9e%e6%87%82%e5%9f%ba%e5%9b%a0%e7%a5%9e%e5%89%aa-crispr","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/17751\/","title":{"rendered":"\u4eba\u9ad4\u57fa\u56e0\u7de8\u8f2f\u662f\u5728\u7de8\u4ec0\u9ebc\uff1f\u4e94\u5206\u9418\u641e\u61c2\u57fa\u56e0\u795e\u526a CRISPR"},"content":{"rendered":"<h2 class=\"aio-icon-title ult-responsive\" data-ultimate-target=\"#Info-box-wrap-7138 .aio-icon-title\" data-responsive-json-new=\"{&quot;font-size&quot;:&quot;&quot;,&quot;line-height&quot;:&quot;&quot;}\"><strong>CRISPR \u7684\u539f\u7406\u8207\u61c9\u7528<\/strong><\/h2>\n<p>2018 \u5e74 11 \u6708\uff0c\u4e2d\u570b\u57fa\u56e0\u7de8\u8f2f\u5bf6\u5bf6\u5f15\u8d77\u8209\u4e16\u8b41\u7136\uff01\u9019\u500b\u4e8b\u4ef6\u7684\u524d\u56e0\uff0c\u8981\u8ffd\u6eaf\u5230 2012 \u5e74\u6a6b\u7a7a\u51fa\u4e16\u7684\u57fa\u56e0\u526a\u5200 CRISPR\uff0c\u8b93\u4eba\u985e\u5f9e\u6b64\u53ef\u7cbe\u6e96\u3001\u5feb\u901f\u3001\u4fbf\u5b9c\u7684\u7de8\u8f2f DNA\u3002\u4f46\u9019\u628a\u526a\u5200\u76ee\u524d\u9084\u6709\u6280\u8853\u74f6\u9838\uff0c\u53ea\u9069\u5408\u6cbb\u7642\u53ef\u62ff\u51fa\u9ad4\u5916\u7684\u514d\u75ab\u7d30\u80de\u3002\u6211\u5011\u9080\u8acb\u4e2d\u7814\u9662\u751f\u7269\u5316\u5b78\u7814\u7a76\u6240\u3001\u5c08\u7814 CRISPR \u7684\u51cc\u5609\u9d3b\u52a9\u7814\u7a76\u54e1\uff0c\u4ecb\u7d39\u9019\u9805\u6b63\u5728\u7ffb\u8f49\u4e16\u754c\u7684\u57fa\u56e0\u795e\u5668\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u7de8\u8f2f\u4eba\u9ad4\u57fa\u56e0\uff0c\u5c31\u662f\u4fee\u6539\u4eba\u9ad4<a href=\"https:\/zh.wikipedia.org\/wiki\/%E8%84%B1%E6%B0%A7%E6%A0%B8%E7%B3%96%E6%A0%B8%E9%85%B8\" target=\"_blank\" rel=\"noopener noreferrer\">\u00a0DNA<\/a>\uff0c\u4e3b\u8981\u52d5\u6a5f\u662f\u6839\u6cbb<a href=\"https:\/zh.wikipedia.org\/zh-tw\/%E7%AA%81%E5%8F%98\" target=\"_blank\" rel=\"noopener noreferrer\">\u57fa\u56e0\u7a81\u8b8a<\/a>\u5f15\u767c\u7684\u75be\u75c5\u3002<\/p>\n<p>\u300c\u4f46\u662f\u745e\u51e1\uff0c\u6211\u5011\u771f\u7684\u9700\u8981\u57fa\u56e0\u7de8\u8f2f\u4f86\u6cbb\u75c5\u55ce?\u300d<\/p>\n<p>\u4e8b\u60c5\u662f\u9019\u6a23\u7684\uff1aDNA \u662f\u751f\u547d\u7684\u85cd\u5716\uff0c\u6307\u63ee\u7d30\u80de\u751f\u7522\u86cb\u767d\u8cea\uff0c\u7dad\u6301\u4eba\u9ad4\u7684\u751f\u9577\u8207\u904b\u4f5c\u3002\u7576 DNA \u7684\u91cd\u8981\u4f4d\u7f6e\u767c\u751f\u7a81\u8b8a\uff0c\u300c\u7d30\u80de\u5de5\u5ee0\u300d\u904b\u4f5c\u6703\u5931\u63a7\uff0c\u5c31\u53ef\u80fd\u9020\u6210\u751f\u7406\u5931\u8abf\uff0c\u751a\u81f3\u50cf\u767d\u8840\u75c5\u7b49\u91cd\u5927\u907a\u50b3\u75be\u75c5\u3002<\/p>\n<p>\u300c\u751f\u75c5\u4e86\uff0c\u53ef\u4ee5\u5403\u85e5\u3002\u4f46\u57fa\u56e0\u7a81\u8b8a\u9020\u6210\u7684\u75be\u75c5\uff0c\u85e5\u7269\u53ea\u80fd\u63a7\u5236\u75c5\u60c5\u3002\u300d\u51cc\u5609\u9d3b\u7e7c\u7e8c\u89e3\u91cb\uff1a\u300c\u56e0\u70ba\u5f9e\u85cd\u5716\u5c31\u932f\u4e86\uff0c\u7d30\u80de\u6c38\u9060\u53ea\u80fd\u88fd\u9020\u932f\u8aa4\u7684\u86cb\u767d\u8cea\u3002\u60f3\u8981\u6839\u6cbb\uff0c\u6700\u597d\u76f4\u63a5\u66f4\u6b63\u85cd\u5716\uff0c\u4fee\u6539 DNA\u3002\u300d<\/p>\n<blockquote>\n<h4><strong>\u57fa\u56e0\u7de8\u8f2f\uff0c\u53ef\u4ee5\u5f9e\u6e90\u982d\u4e0b\u624b\uff0c\u627e\u5230\u932f\u8aa4\u7684 DNA \u7247\u6bb5\uff0c\u7528\u4e00\u628a\u5206\u5b50\u300c\u526a\u5200\u300d\u5207\u958b\uff0c\u5254\u9664\u9019\u500b\u932f\u8aa4\u7684\u57fa\u56e0\uff0c\u6216\u662f\u5728\u7f3a\u53e3\u8655\u300c\u8cbc\u4e0a\u300d\u6b63\u78ba\u7684 DNA \u7247\u6bb5\u3002<\/strong><\/h4>\n<p>&nbsp;<\/p><\/blockquote>\n<div id=\"attachment_8423\" style=\"width: 810px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8423\" class=\"wp-image-8423 size-full\" src=\"http:\/research.sinica.edu.tw\/wp-content\/uploads\/2019\/04\/lin-steven-01.jpg\" alt=\"\u904e\u53bb\u57fa\u56e0\u7a81\u8b8a\u5f15\u767c\u7684\u75be\u75c5\uff0c\u85e5\u7269\u7121\u6cd5\u6839\u6cbb\uff0c\u5fc5\u9808\u7d42\u8eab\u5403\u85e5\u3002\u73fe\u4ee3\u7684\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c\u53ef\u4ee5\u5fb9\u5e95\u6839\u6cbb\u57fa\u56e0\u7f3a\u9677\uff0c\u5c31\u50cf\u7528\u6587\u66f8\u8edf\u9ad4\u4fee\u6539\u932f\u8aa4\u4e00\u6a23\uff1a\u627e\u5230\u932f\u5b57 (\u767c\u73fe\u7a81\u8b8a\u57fa\u56e0)\u3001\u522a\u9664\u932f\u5b57 (\u526a\u4e0b\u7a81\u8b8a\u57fa\u56e0)\u3001\u88dc\u4e0a\u6b63\u78ba\u7684\u5b57 (\u8cbc\u4e0a\u6b63\u78ba\u57fa\u56e0)\u3002\u5716\u8aaa\u8a2d\u8a08\u2502\u9ec3\u66c9\u541b\u3001\u6797\u6d35\u5b89 \u8cc7\u6599\u4f86\u6e90\u2502\u51cc\u5609\u9d3b\" width=\"800\" height=\"542\" \/><p id=\"caption-attachment-8423\" class=\"wp-caption-text\">\u904e\u53bb\u57fa\u56e0\u7a81\u8b8a\u5f15\u767c\u7684\u75be\u75c5\uff0c\u85e5\u7269\u7121\u6cd5\u6839\u6cbb\uff0c\u5fc5\u9808\u7d42\u8eab\u5403\u85e5\u3002\u73fe\u4ee3\u7684\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c\u53ef\u4ee5\u5fb9\u5e95\u6839\u6cbb\u57fa\u56e0\u7f3a\u9677\uff0c\u5c31\u50cf\u7528\u6587\u66f8\u8edf\u9ad4\u4fee\u6539\u932f\u8aa4\u4e00\u6a23\uff1a\u627e\u5230\u932f\u5b57 (\u767c\u73fe\u7a81\u8b8a\u57fa\u56e0)\u3001\u522a\u9664\u932f\u5b57 (\u526a\u4e0b\u7a81\u8b8a\u57fa\u56e0)\u3001\u88dc\u4e0a\u6b63\u78ba\u7684\u5b57 (\u8cbc\u4e0a\u6b63\u78ba\u57fa\u56e0)\u3002 \u5716\u8aaa\u8a2d\u8a08\u2502\u9ec3\u66c9\u541b\u3001\u6797\u6d35\u5b89 \u8cc7\u6599\u4f86\u6e90\u2502\u51cc\u5609\u9d3b<\/p><\/div>\n<p>&nbsp;<\/p>\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p>\u6240\u4ee5\u9996\u5148\uff0c\u5fc5\u9808\u8981\u6709\u4e00\u628a\u7cbe\u6e96\u3001\u80fd\u5920\u526a\u958b DNA \u96d9\u87ba\u65cb\u7684\u597d\u526a\u5200\uff0c<a href=\"https:\/zh.wikipedia.org\/wiki\/CRISPR\" target=\"_blank\" rel=\"noopener noreferrer\">CRISPR\u00a0<\/a>\u5c31\u662f\u7576\u524d\u6700\u597d\u7528\u7684\u4e00\u628a\u3002\u6709\u8da3\u7684\u662f\uff0c\u5b83\u4f86\u81ea\u7d30\u83cc\u7684\u514d\u75ab\u7cfb\u7d71\u3002<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<h2 class=\"contains_subtitle_icon\"><strong><b>\u7d30\u83cc\u88e1\u7684\u57fa\u56e0\u526a\u5200<\/b><\/strong><\/h2>\n<p>1987 \u5e74\uff0c\u65e5\u672c\u79d1\u5b78\u5bb6\u5728\u5927\u8178\u687f\u83cc\u7684\u57fa\u56e0\u9ad4\u767c\u73fe\u4e00\u6bb5\u53e4\u602a\u7684\u898f\u5f8b\u5e8f\u5217\uff0c\u67d0\u4e00\u5c0f\u6bb5 DNA (Repeat) \u6703\u4e00\u76f4\u91cd\u8907\uff0c\u91cd\u8907\u7247\u6bb5\u4e4b\u9593\u53c8\u6709\u4e00\u6a23\u9577\u7684\u9593\u9694 (Spacer)\uff0c\u7528\u9014\u4e0d\u660e\uff0c\u79d1\u5b78\u5bb6\u628a\u9019\u6bb5\u5e8f\u5217\u53eb\u505a\u00a0<a href=\"https:\/zh.wikipedia.org\/wiki\/CRISPR\" target=\"_blank\" rel=\"noopener noreferrer\">CRISPR<\/a>\u00a0(clustered, regularly interspaced, short palindromic repeats)\u3002\u5f8c\u4f86\u767c\u73fe\uff0c\u8a31\u591a\u7d30\u83cc\u90fd\u6709 CRISPR\uff0c\u5b83\u662f\u7d30\u83cc\u514d\u75ab\u7cfb\u7d71\u7684\u4e00\u7a2e\u6a5f\u5236\uff0c\u53ef\u4ee5\u8a18\u61b6\u66fe\u7d93\u4f86\u72af\u7684\u75c5\u6bd2\u3002<\/p>\n<blockquote>\n<h4><strong>\u60f3\u4e0d\u5230\uff0c\u9019\u500b\u770b\u4f3c\u4e0d\u8d77\u773c\u7684 DNA \u7247\u6bb5\uff0c\u5c07\u6703\u5f15\u7206\u57fa\u56e0\u7de8\u8f2f\u7684\u5927\u72c2\u6f6e\uff01<\/strong><\/h4>\n<\/blockquote>\n<p>\u6545\u4e8b\u662f\u9019\u9ebc\u958b\u59cb\u7684\uff1a\u7576\u75c5\u6bd2\u5165\u4fb5\u7d30\u83cc\uff0c\u6703\u628a\u81ea\u5df1\u7684 DNA \u6ce8\u5165\u5230\u7d30\u83cc\u4e2d\uff0c\u4f01\u5716\u9738\u4f54\u7d30\u83cc\u5de5\u5ee0\u7684\u8cc7\u6e90\uff0c\u8907\u88fd\u65b0\u75c5\u6bd2\u3002\u4f46\u7d30\u83cc\u4e5f\u4e0d\u6703\u4e56\u4e56\u6328\u6253\uff0c\u5b83\u5011\u7684\u514d\u75ab\u7cfb\u7d71\u53ef\u4ee5\u8fa8\u8b58\u3001\u6467\u6bc0\u75c5\u6bd2\u7684 DNA\u3002\u9019\u662f\u4e00\u5834\u5fae\u89c0\u4e16\u754c\u7684\u9583\u96fb\u6230\uff0c\u7d30\u83cc\u7684\u53cd\u64ca\u5fc5\u9808\u5920\u5feb\u3001\u5920\u6e96\uff0c\u624d\u6709\u6a5f\u6703\u5b58\u6d3b\uff01<\/p>\n<p>\u6709\u4e9b\u7d30\u83cc\u50e5\u5016\u5b58\u6d3b\u5f8c\uff0c\u6703\u6311\u9078\u4e00\u6bb5\u75c5\u6bd2\u7684 DNA \u788e\u7247\uff0c\u63d2\u5165\u81ea\u5df1\u7684 CRISPR \u5e8f\u5217 (\u589e\u52a0\u4e00\u6bb5 Spacer)\uff0c\u5c31\u50cf\u70ba\u75c5\u6bd2\u5efa\u7acb\u300c\u7f6a\u72af\u8cc7\u6599\u5eab\u300d\u3002\u7576\u75c5\u6bd2\u7b2c\u4e8c\u6b21\u5165\u4fb5\uff0c\u7d30\u83cc\u5c31\u80fd\u4f9d\u9760 CRISPR \u5e8f\u5217\u5feb\u901f\u8a8d\u51fa\u9019\u7a2e\u75c5\u6bd2\uff0c\u7b2c\u4e00\u6642\u9593\u53cd\u6bba\uff0c\u63d0\u9ad8\u5b58\u6d3b\u7387\u3002<\/p>\n<div id=\"attachment_8686\" style=\"width: 488px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8686\" class=\"wp-image-8686\" src=\"http:\/research.sinica.edu.tw\/wp-content\/uploads\/2019\/04\/lin-chia-hung-02.jpg\" alt=\"\u7d30\u83cc\u9047\u5230\u75c5\u6bd2\u5165\u4fb5\uff0c\u7d30\u83cc\u7684 Cas9 \u6703\u526a\u4e0b\u75c5\u6bd2\u7684\u4e00\u6bb5 DNA\uff0c\u63d2\u5728\u81ea\u5df1\u7684\u57fa\u56e0\u7d44\u4e0a\uff0c\u5c31\u597d\u50cf\u70ba\u75c5\u6bd2\u5efa\u7acb\u300c\u7f6a\u72af\u8cc7\u6599\u5eab\u300d\u3002\u5716\u8aaa\u8a2d\u8a08\u2502\u9ec3\u66c9\u541b\u3001\u6797\u6d35\u5b89 \u8cc7\u6599\u4f86\u6e90\u2502\u51cc\u5609\u9d3b\" width=\"478\" height=\"676\" \/><p id=\"caption-attachment-8686\" class=\"wp-caption-text\">\u7d30\u83cc\u9047\u5230\u75c5\u6bd2\u5165\u4fb5\uff0c\u7d30\u83cc\u7684 Cas9 \u6703\u526a\u4e0b\u75c5\u6bd2\u7684\u4e00\u6bb5 DNA\uff0c\u63d2\u5728\u81ea\u5df1\u7684\u57fa\u56e0\u7d44\u4e0a\uff0c\u5c31\u597d\u50cf\u70ba\u75c5\u6bd2\u5efa\u7acb\u300c\u7f6a\u72af\u8cc7\u6599\u5eab\u300d\u3002 \u5716\u8aaa\u8a2d\u8a08\u2502\u9ec3\u66c9\u541b\u3001\u6797\u6d35\u5b89 \u8cc7\u6599\u4f86\u6e90\u2502\u51cc\u5609\u9d3b<\/p><\/div>\n<p>&nbsp;<\/p>\n<p>\u7d30\u83cc\u662f\u5982\u4f55\u8a8d\u51fa\u75c5\u6bd2\u7684\u5462\uff1f\u9996\u5148\uff0c\u7d30\u83cc\u6703\u7528\u820a\u75c5\u6bd2\u7684 DNA \u7247\u6bb5 (Spacer) \u7576\u6a21\u677f\uff0c\u6253\u9020\u4e00\u689d\u4e92\u88dc\u7684\u5f15\u5c0e\u00a0<a href=\"https:\/zh.wikipedia.org\/wiki\/%E6%A0%B8%E7%B3%96%E6%A0%B8%E9%85%B8\" target=\"_blank\" rel=\"noopener noreferrer\">RNA<\/a>\uff0c\u4f8b\u5982\u75c5\u6bd2 DNA \u7684<a href=\"https:\/zh.wikipedia.org\/wiki\/%E6%A0%B8%E9%B9%BC%E5%9F%BA\" target=\"_blank\" rel=\"noopener noreferrer\">\u9e7c\u57fa<\/a>\u662f T\u3001RNA \u662f A\uff0cDNA \u662f G\u3001RNA \u662f C\uff0c\u6216\u662f\u4e92\u76f8\u985b\u5012\u3002\u5f15\u5c0e RNA \u518d\u5229\u7528\u9019\u7a2e\u4e92\u88dc\u95dc\u4fc2\uff0c\u6bd4\u5c0d\u65b0\u75c5\u6bd2 DNA \u7247\u6bb5\uff0c\u5982\u679c\u53ef\u4ee5\u4e92\u88dc\uff0c\u8868\u793a\u65b0\u820a\u75c5\u6bd2\u76f8\u540c\u3002<\/p>\n<p>\u7136\u5f8c\uff0c\u4e00\u7a2e\u53ef\u4ee5\u5207\u5272 DNA \u7684\u9175\u7d20 Cas9 (\u6b66\u88dd\u8b66\u5bdf)\uff0c\u6703\u6293\u8457\u9019\u6bb5\u5f15\u5c0e RNA (\u5acc\u72af\u8cc7\u6599)\uff0c\u524d\u53bb\u300c\u76e4\u67e5\u300d\u65b0\u75c5\u6bd2\u7684 DNA\uff0c\u770b\u770b\u6709\u6c92\u6709\u8ddf\u5f15\u5c0e RNA \u4e92\u88dc\u7684\u6bb5\u843d\u3002\u9019\u4e00\u6b21\u53cd\u904e\u4f86\uff0cRNA \u662f A\uff0cDNA \u662f T\uff1bRNA \u662f C\uff0cDNA \u662f G\uff0c\u6216\u662f\u4e92\u76f8\u985b\u5012\u3002<\/p>\n<p>\u4e00\u65e6\u627e\u5230\u4e86\uff0cCas9 \u7acb\u523b\u526a\u958b\u300c\u88ab\u8a8d\u51fa\u300d\u7684 DNA \u7247\u6bb5\u3002DNA \u88ab\u526a\u65b7\u6467\u6bc0\uff0c\u75c5\u6bd2\u5c31\u6c92\u6232\u5531\u4e86\u3002\u9019\u7a2e\u7d30\u83cc\u7684\u514d\u75ab\u6a5f\u5236\uff0c\u7a31\u70ba CRISPR-Cas9\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center;\"><strong>\u8981\u770b\u66f4\u5b8c\u6574\u7684\u7cbe\u91c7\u6587\u7ae0\uff0c\u8acb\u81f3\u7814\u4e4b\u6709\u7269\u5b98\u7db2\uff1a<\/strong><\/h2>\n<h2 style=\"text-align: center;\"><em><a href=\"http:\/research.sinica.edu.tw\/gene-editing-crispr-lin-chia-hung\/\">http:\/research.sinica.edu.tw\/gene-editing-crispr-lin-chia-hung\/<\/a><\/em><\/h2>\n<h2 style=\"text-align: center;\"><strong>\uff08\u8d95\u5feb\u9ede\u9032\u4f86\u5594\uff01\u9084\u6709\u66f4\u591a\u7cbe\u91c7\u5716\u6587\uff01\uff09<\/strong><\/h2>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>CRISPR \u7684\u539f\u7406\u8207\u61c9\u7528 2018 \u5e74 11 \u6708\uff0c\u4e2d\u570b\u57fa\u56e0\u7de8\u8f2f\u5bf6\u5bf6\u5f15\u8d77\u8209\u4e16\u8b41\u7136\uff01\u9019\u500b\u4e8b\u4ef6\u7684\u524d\u56e0\uff0c\u8981\u8ffd\u6eaf\u5230 2 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":17752,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[4],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/17751"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=17751"}],"version-history":[{"count":2,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/17751\/revisions"}],"predecessor-version":[{"id":24442,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/17751\/revisions\/24442"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/17752"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=17751"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=17751"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=17751"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}