◆◇學術研討會◇◆

  Frontiers in Bioorganic Chemistry-2000

時　　間：八十八年十一月廿九日至十二月二日

地　　點：本院學術活動中心一樓

主辦單位：中央研究院、行政院國家科學委員會、中國化學會、國家衛
	  生研究院

Monday,	November 29, 1999

08:00-08:40 Registration

	    Opening Ceremony

08:40-08:50 Sunney I. Chan, Vice President of Academia Sinica

	    Welcome

08:50-09:00 Yuan T. Lee, President of Academia Sinica

	    Opening Remarks

	    Molecular Genomics

	    Chairman: Chien-Chung Cheng, Academia Sinica

09:00-10:00 Peter B. Dervan, Caltech

	    Topic:"Regulation of Gene Expression by
	    Synthetic DNA Binding Ligands"

	    Chairman: Kuang-Lieh Lu, Academia Sinica

10:30-11:30 Jacqueline K. Barton, Caltech

	    Topic: "DNA Damage and Repair: Chemistry at a
	    Distance"

11:30-12:30 Reuben Jih-Ru Hwu, Academia	Sinica & National Tsing	
	    Hua	University

	    Topic: "New Photo-induced DNA Cleavage Agents"

	    Drug Discovery

	    Chairman: Ming-Chu Hsu, National Health Research
	    Institutes

14:30-15:30 Thomas L. James, UCSF

	    Topic: "RNA Structures: A Basis for Ligand 
	    Discovery"

	    Chairman: Chun-Chen	Liao, National Tsing Hua 
	    University

16:00-17:00 Anthony W. Czarnik,	Illumina, San Diego

	    Topic: "Selective Small Molecule-RNA Complexation: 
	    A New World	for Drug Discovery"

17:00-18:00 Chaitan S. Khosla, Stanford	University

	    Topic: Polyketide Synthase

Tuesday, November 30, 1999

	    Catalytic Antibodies

	    Chairman: Lee-Chiang Lo, National Taiwan University

08:40-09:40 Richard A. Lerner, Scripps Research	Institute

	    Topic: "Catalytic Antibodies"

	    Chairman: Bon-Chu Chung, Academia Sinica

10:30-11:30 Ian	Wilson,	Scripps	Research Institute

	    Topic: "Structure of Catalytic Antibodies"

11:30-12:30 Peter G. Schultz, UC Berkeley

	    Topic: "Lessons from the Immune System: From 
	    Catalysis to Materials"

14:00-17:00 Golf or Tour-National Palace Museum

	    Wednesday, December	1, 1999

	    Carbohydrate Therapeutics

	    Chairman: Biing-Jiun Uang, National	Tsing Hua 
	    University

09:00-10:00 Samuel J. Danishefsky, Sloan Kettering Cancer 
	    Institute &	Columbia University

	    Topic: "On the Power of Organic Synthesis"

	    Chairman: Chun-Hung	Lin, Academia Sinica

10:30-11:30 Chi-Huey Wong, Scripps Research Institute

	    Topic: "Chemoenzymatic Approach to Carbohydrate-
	    Receptor Interactions"

11:30-12:30 Raymond Dwek, University of	Oxford

	    Topic: "Glycobiology: Toward Understanding the 
	    Function of	Sugars"

	    Receptors and Enzymes

	    Chairman: Chao-Hsiung Lin, National	Yang Ming 
	    University

14:00-15:00 Kim	D. Janda, Scripps Research Institute

	    Topic: "Merging Chemistry and Biology: A 
	    Combinatorial Approach"

	    Chairman: Shui-Tien	Chen, Academia Sinica

15:30-16:30 Hung-Wen Ben Liu, University of Minnesota

	    Topic: "Learning Nature's Strategies of Making 
	    Deoxysugars: Pathways, Mechanism, and

	    Combinatorial Biosynthetic Applications"

16:30-17:30 Kevan M. Shokat, UCSF

	    Topic: "Unnatural Ligands for Engineered Receptors: 
	    New	Tools for Chemical Biology"

Thursday, December 2, 1999

	    Molecular Evolution

	    Chairman: Jim-Ming Fang, National Taiwan University

09:00-10:00 Gerald Joyce, Scripps Research Institute

	    Topic: "Directed Molecular Evolution"

	    Chairman: Sunney I.	Chan, Academia Sinica

10:30-11:30 Steve A. Benner, University	of Florida

	    Topic: "Biomolecules as Products of Natural 
	    Evolution"