◆◇學術研討會◆◇ 第二屆泛太平洋會議─國際醣質生命科學研討會 INTERNATIONAL SYMPOSIUM on Sialobiology and Other Novel Forms of Glycosylation Second Pan-Pacific Conference Institute of Biological Chemistry, Academia Sinica November 9（Monday）-13（Friday）,1998 Location：The Activity Center, Academia Sinica Program Schedule ┌─────┬───────┬────────┬───────┐ │ │ Morning │ Afternoon │ Evening │ ├─────┼───────┼────────┼───────┤ │Sun,Nov 8 │ │15:00-17:30 │18:00-20:00 │ │ │ │Registration │Get Together │ │ │ │ │Party │ ├─────┼───────┼────────┼───────┤ │Day 1 │9:00 Opening │14:00-15:40 │ │ │Mon,Nov 9 │ Remarks │Session 1(cont.)│ │ │ │9:20-10:05 │：IL 4-7, OP 4-5│ │ │ │ PL-1 │16:00-18:00 │Social Events │ │ │10:30-12:00 │Poster Session 1│ │ │ │Session 1：IL │ │ │ │ │ 1-3, OP 1-3 │ │ │ ├─────┼───────┼────────┼───────┤ │Day 2 │9:00-9:45 PL-2│14:00 - 15:40 │ │ │Tue,Nov 10│9:45-10:25 │Session 3：IL │ │ │ │Session 2：IL8│13-16, OP 6-7 │ │ │ │ -9│16:00-18:00 │Social Events │ │ │10:50 - 11:50 │Poster Session 2│ │ │ │Session 2 (con│ │ │ │ │t.) : IL 10-12│ │ │ ├─────┼───────┼────────┴───────┤ │Day 3 │9:00-10:00 │ │ │Wed,Nov 11│Session 4：IL │Lunch, Excursion and Dinner │ │ │ 17-19 │ │ ├─────┼───────┼────────┬───────┤ │Day 4 │9:00-9:45 PL-3│14:00 - 15:00 │18:00-20:00 │ │Thu,Nov 12│9:45-10:25 │Session 5 │Symposium │ │ │Session 5：IL │(cont.)： │Banquet │ │ │ 20-21│IL25-26,OP10-11 │ │ │ │10:50-12:15 │15:30 - 16:30 │ │ │ │Session 5(cont│Poster Session3 │ │ │ │.) : │ │ │ │ │IL22-24,OP 8-9│ │ │ ├─────┼───────┼────────┴───────┤ │Day 5 │9:00-10:35 │ │ │Fri,Nov 13│Session 6：IL │ │ │ │ 27-30, OP-12│ │ │ │10:35 Closing │ │ │ │Remarks │ │ └─────┴───────┴────────────────┘ PL：Plenary Lectures, 45 min. each IL：Invited Lectures, 20 min. each (15-min. talk and 5-min. discussion) OP：Oral Presentation selected from Poster Abstracts, 15 min. for OP-9 and OP-12, 10 min. for all others, inclusive of discussion Venue： 1) The morning sessions on Wednesday (Nov 11)and Friday (Nov 13) will be held at the Institute of Biological Chemistry. 2) Registration and Get-Together Party on Sunday(Nov8), all sessions on Monday (Nov 9), Tuesday (Nov 10) and Thursday (Nov 12) will be held at the Activity Center. 3) Registration and Information Desk remains open throughout the symposium, from 8:30 - 16:00 ______________________________________________________ Nov. 8, Sunday (Activity Center) 15:00 - 17:30 Registration 18:00 - 20:00 GET-TOGETHER PARTY Day 1：Monday, Nov. 9 (Activity Center) 9:00 Opening Remarks & Address by the President of Academia Sinica, Dr. Yuan- Tseh Lee（李遠哲） 9:20-10:05 Plenary Lecture 1 William J. Lennarz, The Role of Glycoproteins in Gamete Interactions Involved in Fertilization Chair：Yasuo Inoue（井上康男） Session 1 Occurrence, Chemistry and Biology of Sialic Acids Chairs: Gerald W. Hart and Makoto Kiso 10:30-10:50 IL-1 Varki AP , Diversity in the N- and O-Acyl Groups of the Sialic Acids 10:50-11-10 IL-2 Schauer R , Biosynthesis and Biology of N-glycolylneuraminic Acid 11:10-11:30 IL-3 Lee YC , Lactonization of Polysialic Acids of α-(2-8)- Linkages 11:30-11:40 OP-1 Kannagi R , Cyclic Sialic Acid: A New Regulatory Mechanism of Selectin Ligand Activity 11:40-11:50 OP-2 Lin CH（林俊宏）, Lactonization of α2,8-Oligosialic Acids Using Capillary Electrophoresis Analysis 11:50-12:00 OP-3 Tseng K,The Analysis of Anionic Oligosaccharides from the Egg Jelly Coats of Xenopus laevis by HPLC & MALDI-FTMS Session 1 (continued) Chairs: Frederic A. Troy II and Monica M. Palcic 14:00-14:20 IL-4 Inoue S(井上貞子),New Findings in KDN Glycobiology:From lower vertebrates to human 14:20-14:40 IL-5 Kitajima K , Occurrence of Oligosialic Acid Residues in Vertebrate Glycoproteins 14:40-15:00 IL-6 von Itzstein M , Recent Adventures in the Chemistry and Biochemistry of Sialic Acid- Recognizing Proteins 15:00-15:10 OP-4 Lin SL（林淑玲）, Analysis of Oligo/polysialic Acids on Biologically Active Glycoproteins by High Performance Anion-Exchange Chromatography (HPAEC) 15:10-15:20 OP-5 Kiefel MJ , Synthesis of Novel Sialosides as Ligands for the Development of Affinity Chromatography Matrices 15:20-15:40 IL-7 Liu DT（劉德勇）, A New Family of Pattern Recognition Molecules from the Hemolymph of Tachypleus tridentatus, the Taiwanese Horseshoe Crab 16:00-18:00 POSTER SESSION 1 ─────────────────────────────── Day 2：Tuesday, Nov. 10 (Activity Center) 9:00-9:45 Plenary Lecture 2 Irwin J. Goldstein , Sialic Acid-Recognizing Plant Lectins Chair：Sunny I. Chan（陳長謙） Session 2: Lectins and Sialic Acid Recognition Chairs：Sen-itiroh Hakomori and Inn-Ho Tsai（蔡蔭和） 9:45-10:05 IL-8 Karlsson KA , Sialic Acid Recognition by Bacterial Adhesins 10:05-10:25 IL-9 Crocker PR , Sialic Acid Recognition by Sialoadhesin and Related Members of the Immunoglobulin Superfamily Session 2 (continued) Chairs：Paul R. Crocker and Sergio Schenkman 10:50-11:10 IL-10 Schnaar R , Sialoglycoconjugate Recognition by a Nervous System Lectin-Functional Implications of Myelin-Associated Glycoprotein Binding to Brain Gangliosides 11:10-11:30 IL-11 Rougon G , The Role of Polysialic Acids in Cell Migration and Neuronal Plasticity 11:30-11:50 IL-12 Bovin NV , New Principle of Influenza Hemagglutinin Inhibition 12:00-12:30 Symposium Photograph Session Session 3: Sialyltransferase and Polysialyltransferases Chairs：Ajit P. Varki and Ying-Chieh Tsai（蔡英傑） 14:00-14:20 IL-13 Marth JD , Sialyltransferase Control of Immune Physiology 14:20-14:40 IL-14 Tsuji S , Molecular Cloning and Characterization of Sialyltransferases and Polysialic Acid Synthases 14:40-14:50 OP-6 Bird M,Photoaffinity Labelling of a Sialyltransferase Using CDP-ethanolamine-ASA Chairs：Roland Schauer and Karen J. Colley 14:50-15:10 IL-15 Colley KJ , Sialyltransferase Isoforms 15:10-15:30 IL-16 Troy FA , Molecular Mechanisms of Polysialylation Catalyzed by α2,8-Polysialyltransferases 15:30-15:40 OP-7 Laroy W , Structure-Function Analysis of Human ST6Gal I 16:00-18:00 POSTER SESSION 2 ─────────────────────────────── Day 3 : Wednesday, Nov. 11 (Institute of Biological Chemistry) Session 4：Sialidases Chairs：Su-Chen Li and Yen-Chywan Liaw （廖彥銓） 9:00-9:20 IL-17 Taylor G , The Sialidase Superfamily: Structural Theme and Variations 9:20-9:40 IL-18 Li YT,Specificity and Structure of a NeuAcα2->3Gal Specific Sialidase, Sialidase L 9:40-10:00 IL-19 Miyagi T, Pathophysiological Expression of Mammalian Sialidases ─────────────────────────────── Day 4：Thursday, Nov. 12 (Activity Center) 9:00-9:45 Plenary Lecture 3 Robert L. Hill , Porcine Submaxillary Mucin. Structure and Assembly Chair：Darrell T. Liu（劉德勇） Session 5: Current Topics in Glycobiology and Glycopathology Chairs: Ronald Schnaar and Kiyoshi Furukawa 9:45-10:05 IL-20 Hart GW , Current Status of Cytoplasmic and Nuclear Glycosylation 10:05-10:25 IL-21 Hakomori S , Cell Adhesion Coupled with Signal Transduction, Mediated by Glycosphingolipid Microdomain (Glycosignaling Domain) Session 5 (continued) Chairs：Karl-Anders Karlsson and Shizuo Handa 10:50-11:10 IL-22 Yu R, Regulation of Ganglioside Metabolism in the Nervous System 11:10-11:30 IL-23 Hopwood JJ , Lysosomal Disorders from Storage of Glycosaminoglycans 11:30-11:50 IL-24 Lin JY（林榮耀）, Studies on the D-Galactose Binding Site of Three Toxic Lectins, Isoabrins 11:50-12:00 OP-8 Chung CS（鍾<吉吉吉>生）, A27L Protein Mediates Vaccinia Virus Interaction with Cell Surface Heparan Sulfate 12:00-12:15 OP-9 Endo T , Detection of Sialylated O-Mannosyl Glycans in Rabbit Skeletal Muscle α-Dystroglycan Session 5 (continued) Chairs：Carolyn Bertozzi and Albert Wu（吳明道） 14:00-14:20 IL-25 Ferguson MAJ, Glycosylphosphatidylinositol (GPI) Membrane Anchors:A Target for Anti-parasite Therapy 14:20-14:40 IL-26 Schenkman S , Structure and Funciton of Trypanosoma cruzi Trans-sialidase and Sialic Acid Acceptors 14:40-14:50 OP-10 Hwa KY（華國媛）, Structural Analysis on the Asn-linked Glycans of Protozoan Parasite Trypanosoma brucei brucei: From Structure to Biosynthesis 14:50-15:00 OP-11 Khoo KH （邱繼輝）, Structural Probing of the Developmental Stage-specific Glycosylation Profile of Schistosomes 15:30-16:30 POSTER SESSION 3 18:00-20:00 Banquet Dinner ─────────────────────────────── Day 5：Friday, Nov. 13 (Institute of Biological Chemistry) Session 6：Chemical Approaches to Glycobiology Chairs：Shih-Hsiung Wu（吳世雄）and Chun-Cheng Lin （林俊成） 9:00-9:20 IL-27 Palcic MM , Monitoring Biosynthesis of Oligosaccharides in Single Cells 9:20-9:40 IL-28 Taguchi T , Structure and Biosynthesis of Complex Multiantennary Carbohydrate Chains Chairs : Yuan C. Lee and Mark von Itzstein 9:40-10:00 IL-29 Bertozzi C, Chemical Approaches to Glyobiology 10:00-10:15 OP-12 Reutter W , Biochemical Engineering of Sialic Acid in Surface Glycoconjugates by N- Propanoylmannosamine:Biological Implication in T-Lymphocytes, Lymphoma Cells and Glia Cells 10:15-10:35 IL-30 Shiba T , Synthesis of Sialylglycosides as Key Tools of Biological Studies 10:35-10:40 Closing Remarks