¡»¡º¾Ç³N¬ã°Q·|¡»¡º INTERNATIONAL SYMPOSIUM on Sialobiology and Other Novel Forms of Glycosylation Second Pan-Pacific Conference Institute of Biological Chemistry, Academia Sinica November 9¡]Monday¡^-13¡]Friday¡^,1998 Location¡GThe Activity Center, Academia Sinica Program Schedule ¢z¢w¢w¢w¢w¢w¢w¢s¢w¢w¢w¢w¢w¢w¢s¢w¢w¢w¢w¢w¢w¢w¢s¢w¢w¢w¢w¢w¢w¢w¢{ ¢x ¢xMorning ¢x Afternoon ¢x Evening ¢x ¢u¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢t ¢xSun, Nov 8 ¢x ¢x15:00 - 17:30 ¢x18:00 - 20:00 ¢x ¢x ¢x ¢xRegistration ¢xGet Together ¢x ¢x ¢x ¢x ¢xParty ¢x ¢u¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢t ¢xDay 1 ¢x9:00 Opening¢x14:00 - 15:40 ¢x ¢x ¢x ¢x Remarks¢xSession 1 ¢x ¢x ¢xMon, Nov 9 ¢x9:20-10:05 ¢x(cont.):IL4-7,¢x ¢x ¢x ¢x PL-1 ¢x OP 4-5¢x Social Events¢x ¢x ¢x10:30-12:00 ¢x16:00-18:00 ¢x ¢x ¢x ¢xSession 1:IL¢xPoster Session¢x ¢x ¢x ¢x 1-3, OP 1-3¢x 1 ¢x ¢x ¢u¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢t ¢xDay 2 ¢x9:00-9:45 ¢x14:00 - 15:40 ¢x ¢x ¢x ¢x PL-2 ¢xSession 3¡GIL ¢x ¢x ¢xTue, Nov 10 ¢x9:45-10:25 ¢x13-16, OP 6-7 ¢x ¢x ¢x ¢xSession 2 ¢x16:00 - 18:00 ¢x Social Events¢x ¢x ¢x IL 8-9 ¢xPoster Session¢x ¢x ¢x ¢x10:50-11:50 ¢x 2 ¢x ¢x ¢x ¢xSession 2 ¢x ¢x ¢x ¢x ¢x (cont.):¢x ¢x ¢x ¢x ¢x IL10-12 ¢x ¢x ¢x ¢u¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢r¢w¢w¢w¢w¢w¢w¢w¢t ¢x ¢x9:00-10:00 ¢x ¢x ¢xDay 3 ¢xSession 4¡G ¢xLunch, Excursion and Dinner ¢x ¢xWed, Nov 11 ¢x IL 17-19¢x ¢x ¢u¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢s¢w¢w¢w¢w¢w¢w¢w¢t ¢x ¢x9:00-9:45 ¢x14:00-15:00 ¢x18:00-20:00 ¢x ¢x ¢x PL-3 ¢xSession 5 ¢xSymposium ¢x ¢xDay 4 ¢x9:45-10:25 ¢x (cont.)¡G¢xBanquet ¢x ¢xThu, Nov 12 ¢xSession 5¡G ¢x IL 25-26,¢x ¢x ¢x ¢x IL 20-21¢x OP 10-11 ¢x ¢x ¢x ¢x10:50-12:15 ¢x15:30-16:30 ¢x ¢x ¢x ¢xSession 5 ¢xPoster Session¢x ¢x ¢x ¢x (cont.) :¢x 3 ¢x ¢x ¢x ¢x IL 22-24,¢x ¢x ¢x ¢x ¢x OP 8-9 ¢x ¢x ¢x ¢u¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢q¢w¢w¢w¢w¢w¢w¢w¢r¢w¢w¢w¢w¢w¢w¢w¢t ¢x ¢x9:00-10:35 ¢x ¢x ¢xDay 5 ¢xSession 6¡G ¢x ¢x ¢xFri, Nov 13 ¢x IL 27-30,¢x ¢x ¢x ¢x OP-12 ¢x ¢x ¢x ¢x10:35 ¢x ¢x ¢x ¢x Closing¢x ¢x ¢x ¢x Remarks¢x ¢x ¢|¢w¢w¢w¢w¢w¢w¢r¢w¢w¢w¢w¢w¢w¢r¢w¢w¢w¢w¢w¢w¢w¢w¢w¢w¢w¢w¢w¢w¢w¢} PL¡GPlenary Lectures, 45 min each IL¡GInvited Lectures, 20 min each (15-min talk and 5-min discussion) OP¡GOral Presentation selected from Poster Abstracts, 15 min for OP-9 and OP-12, 10 min for all others, inclusive of discussion Venue¡G 1) The morning sessions on Wednesday (Nov 11) and Friday (Nov 13) will be held at the Institute of Biological Chemistry. 2) Registration and get-Together Party on Sunday (Nov 8), all sessions on Monday (Nov 9), Tuesday (Nov 10) and Thursday (Nov 12) will be held at the Activity Center. 3) Registration and Information Desk remains open throughout the symposium, from 8:30 -16:00 Nov 8, Sunday (Activity Center) 15:00 - 17:30 Registration 18:00 - 20:00 GET-TOGETHER PARTY Day 1¡GMonday, Nov 9 (Activity Center) ¡Ã¡Ã¡Ã 9:00 Opening Remarks & Address by the President of Academia Sinica, Dr. Yuan-Tseh Lee 9:20-10:05 Plenary Lecture 1 William J. Lennarz, The Role of Glycoproteins in Gamete Interactions Involved in Fertiliza- tion Chair¡GYasuo Inoue Session 1 Occurrence, Chemistry and Biology of Sialic Acids Chairs: Gerald W. Hart and Makoto Kiso 10:30-10:50 IL-1 Varki AP , Diversity in the N- and O-Acyl Groups of the Sialic Acids 10:50-11-10 IL-2 Schauer R , Biosynthesis and Biology of N-glycolylneuraminic Acid 11:10-11:30 IL-3 Lee YC , Lactonization of Polysialic Acids of £\-(2-8)-Linkages 11:30-11:40 OP-1 Kannagi R , Cyclic Sialic Acid: A New Regulatory Mechanism of Selectin Ligand Activity 11:40-11:50 OP-2 Lin CH , Lactonization of £\-2, 8-Oligosialic Acids Using Capillary Electrophoresis Analysis 11:50-12:00 OP-3 Tseng K , The Analysis of Anionic Oligosaccharides from the Egg Jelly Coats of Xenopus laevis by HPLC & MALDI-FTMS Session 1 (continued) Chairs: Frederic A. Troy II and Monica M. Palcic 14:00-14:20 IL-4 Inoue S , New Findings in KDN Glycobiology : From lower vertebrates to human 14:20-14:40 IL-5 Kitajima K , Occurrence of Oligosialic Acid Residues in Vertebrate Glycoproteins 14:40-15:00 IL-6 von Itzstein M , Recent Adventures in the Chemistry and Biochemistry of Sialic Acid-Recognizing Proteins 15:00-15:10 OP-4 Lin SL , Analysis of Oligo/polysialic Acids on Biologically Active Glycopro -teins by High Performance Anion-Exchange Chromatography (HPAEC) 15:10-15:20 OP-5 Kiefel MJ , Synthesis of Novel Sialosides as Ligands for the Development of Affinity Chromatography Matrices 15:20-15:40 IL-7 Liu DT , A New Family of Pattern Recognition Molecules from the Hemolymph of Tachypleus tridentatus, the Taiwanese Horseshoe Crab 16:00-18:00 POSTER SESSION 1 Day 2¡GTuesday, Nov 10 (Activity Center) ¡Ã¡Ã¡Ã 9:00-9:45 Plenty Lecture 2 Irwin J. Goldstein , Sialic Acid-Recognizing Plant Lectins Chair¡GKung-Tsung Wang Session 2: Lectins and Sialic Acid Recognition Chairs¡GSen-itiroh Hakomori and Inn-Ho Tsai 9:45-10:05 IL-8 Karlsson KA , Sialic Acid Recognition by Bacterial Adhesins 10:05-10:25 IL-9 Crocker PR , Sialic Acid Recognition by Sialoadhesin and Related Members of the Immunoglobulin Superfamily Session 2 (continued) Chairs¡GPaul R. Crocker and Sergio Schenkman 10:50-11:10 IL-10 Schnaar R , Sialoglycoconjugate Recognition by a Nervous System LectinFunctional Implications of Myelin- Associated Glycoprotein Binding to Brain Gangliosides 11:10-11:30 IL-11 Rougon G , The Role of Polysialic Acids in Cell Migration and Neuronal Plasticity 11:30-11:50 IL-12 Bovin NV , New Principle of Influenza Hemagglutinin Inhibition 12:00-12:30 Symposium Photograph session Session 3: Sialyltransferase and Polysialyltransferases Chairs¡GAjit P. Varki and Ying-Chieh Tsai 14:00-14:20 IL-13 Marth JD , Sialyltransferase Control of Immune Physiology 14:20-14:40 IL-14 Tsuji S , Molecular Cloning and Characterization of Sialyltransferases and Polysialic Acid Synthases 14:40-14:50 OP-6 Bird M , Photoaffinity Labelling of a Sialyltransferase Using CDP-ethanolamine-ASA Chairs¡GRoland Schauer and Karen J. Colley 14:50-15:10 IL-15 Colley KJ , Sialyltransferase Isoforms 15:10-15:30 IL-16 Troy FA , Molecular Mechanisms of Polysialylation Catalyzed by £\-2, 8-Polysialyltransferases 15:30-15:40 OP-7 Laroy W , Structure-Function Analysis of Human ST6Gal I 16:00-18:00 POSTER SESSION 2 Day 3 : Wednesday, Nov 11 (Institute of Biological Chemistry) sion 4¡GSialidases Chairs¡GSu-Chen Li and Yen-Chywan Liaw 9:00-9:20 IL-17 Taylor G , The Sialidase Superfamily: Structural Theme and Variations 9:20-9:40 IL-18 Li YT , Specificity and Structure of a NeuAc£\2->3Gal Specific Sialidase,Sialidase L 9:40-10:00 IL-19 Miyagi T, Pathophysiological Expression of Mammalian Sialidases Day 4¡GThursday, Nov 12 (Activity Center) ¡Ã¡Ã¡Ã 9:00-9:45 Plenary Lecture 3 Robert L. Hill , Porcine Submaxillary Mucin. Structure and Assembly Chair¡GDarrel T. Liu Session 5: Current Topics in Glycobiology and Glycopath- ology Chairs: Ronald Schnaar and Kiyoshi Furukawa 9:45-10:05 IL-20 Hart GW , Current Status of Cytoplasmic and Nuclear Glycosylation 10:05-10:25 IL-21 Hakomori SI , Cell Adhesion Coupled with Signal Transduction, Mediated by Glycosphingolipid Microdomain (Glycosignaling Domain) Session 5 (continued) Chairs¡GKarl-Anders Karlsson and Shizuo Handa 10:50-11:10 IL-22 Yu R , Regulation of Ganglioside Metabolism in the Nervous System 11:10-11:30 IL-23 Hopwood JJ , Lysosomal Disorders from Storage of Glycosaminoglycans 11:30-11:50 IL-24 Lin JY , Studies on the D-Galactose Binding Site of Three Toxic Lectins, Isoabrins 11:50-12:00 OP-8 Chung CS , A27L Protein Mediates Vaccinia Virus Interaction with Cell Surface Heparan Sulfate 12:00-12:15 OP-9 Endo T , Detection of Sialylated O-Mannosyl Glycans in Rabbit Skeletal Muscle £\-Dystroglycan Session 5 (continued) Chairs¡GCarolyn Bertozzi and Albert Wu 14:00-14:20 IL-25 Ferguson MAJ, Glycosylphosphatidy- linositol (GPI) Membrane Anchors: A Target for Anti- parasite Therapy 14:20-14:40 IL-26 Schenkman S , Structure and Funciton of Trypanosoma cruzi Trans-sialidase and Sialic Acid Acceptors 14:40-14:50 OP-10 Hwa KY , Structural Analysis on the Asn-linked Glycans of Protozoan Parasite Trypanosoma brucei brucei: From Structure to Biosynthesis 14:50-15:00 OP-11 Khoo KH , Structural Probing of the Developmental Stage-specific Glycosylation profile of Schistosomes 15:30-16:30 POSTER SESSION 3 18:00-20:00 Banquet Dinner Day 5¡GFriday, Nov 13 ¡Ã¡Ã¡Ã (Institute of Biological Chemistry) Session 6¡GChemical Approaches to Glycobiology Chairs¡GSunney I. Chan and Shih-Hsiung Wu 9:00-9:20 IL-27 Palcic MM , Monitoring Biosynthesis of Oligosaccharides in Single Cells 9:20-9:40 IL-28 Taguchi T , Structure and Biosynthesis of Complex Multiantennary Carbohydrate Chains Chairs : Yuan C. Lee and Mark von Itzstein 9:40-10:00 IL-29 Bertozzi C , Chemical Approaches to Glyobiology 10:00-10:15 OP-12 Reutter W , Biochemical Engineering of Sialic Acid in Surface Glycoconjugates by N-Propanoylmannosamine :Biological Implication in T-Lymphocytes, Lymphoma Cells and Glia Cells 10:15-10:35 IL-30 Shiba T , Synthesis of Sialylglycosides as Key Tools of Biological Studies 10:35-10:40 Closing Remarks