《學術研討會》

  「國際生物物理及結構生物學研討會」暨「中華民國生物物理學會成立大會」

      主辦單位：生物醫學科學研究所

      時間：五月十一日∼十三日

      地點：生醫所地下一樓會議室

      五月十一日

      09：00∼10：40  Inauguration ceremony for	Biophysical 
      Society of ROC

      Scientific sesion	I：Ion channels（主持人：高閬仙）

      11：05∼11：20  開幕致辭（吳成文）

      11：20∼12：10  錢永佑  Insight into the molecular basis of 
      key functions of voltage-gated calcium channels.

      12：10∼12：25  李權益  On the activation-inactivation 
      coupling in voltage-activated potassium and sodium channels.

      12：25∼12：40  蘇銘嘉  Mode of Inhibition of potassium 
      currents in cardiac tissues by chemical principles from plant
      and synthesis.

      12：40∼12：55  符文美  Regulation of postsynaptic responses
      by CGRP and ATP at developing neuromuscular neuronal factors
      co-released with neurotransmitters may play an important role
      in synaptic development and function.

      12：55∼13：10  高閬仙  Role of Na+/Ca2+ exchange	in regulation
      of cytosolic Ca2+	and secretion in chromaffin cells.

      Scientific session II Cellular Biophysics（主持人：魏耀揮）

      14：00∼14：50  Martin D.	Brand：Protein leak in 
      Mitochondria and cells

      14：50∼15：05  潘容隆  Functional size analysis of 
      thylakoid	protein	kinases	determined by radiation
      inactivation technique.

      15：05∼15：20  鍾邦柱  Structure	and function tudies of 
      cytochrome P450c21.

      15：20∼15：35  劉燦榮  Laser visco diffractometer 
      monitoring of oxidant-induced change of deformability
      profiles and their correlation with the alteration of
      cellular properties of normal and	pathologic
      erythrocytes.

      15：35∼15：50  徐邦達  The heterogeneity	of photosystem II 
      in chlorophyll-b deficient mutants of rice.

      15：50∼16：05  魏耀揮  Studies on the roles of mitochondrial
      DNA mutations in cell bioenergetics using	cytoplasmic transfer
      technique.

      Scientific session III Molecular Interactions（主持人：張固
      剛）

      16：15∼16：30  李寬容  Interaction of probucol and caffeic 
      acid phenethyl ester with	human low density lipoprotein and
      liposomes.

      16：30∼16：45  廖淑惠  Structural model for the reaction	
      mechanism	of glutamine synthetase,based on crystal structures
      of enzyme-substrate complexes.

      16：45∼17：00  林苕呤  The role of surface tension in 
      glubular proteins	stabilization.

      17：00∼17：15  張固剛  Kinetic properties of glutathione	
      transferase in reverse micelles.

      17：15∼17：30  P. Voelker：An introduction to associating 
      system in	analytical ultracentrifuge.

      五月十二日

      Scientic session IV NMR Spectroscopy（主持人：吳文桂、甘魯生）

      09：00∼09：50  何  潛  Designing	novel hemoglobins: a 
      model for	allosteric proteins.

      09：50∼10：05  余  靖  The NMR studies of snake venom 
      proteins from Taiwan Cobra (naja naja atra)

      10：05∼10：20  呂平江  Solution conformation of the NMDA	
      antagonist cronantokin T.

      10：20∼10：35  譚嘉莉  NMR structural studies of	RC-RNase: 
      A	ribonuclease with cell agglutinating and cytotoxic activities.

      10：35∼10：50  甘魯生  A	NH-H hydrogen-bonded 1H	NMR study 
      of hairpin DNA triplex containing	modified base.

      10：50∼11：05  黃文彰  Solid state 2H NMR study of a 
      single-stranded homopurine oligo-	de-oxynucleotide.

      Scientific session V Biophysical Techniques I（主持人：林宗
      義）

      11：15∼11：30  白果能  Application of laser induced 
      fluorescence detection to	DNA restriction	mapping.

      11：30∼11：45  范文祥  Construction and application of the 
      near field scanning optical microscope.

      11：45∼12：00  H. Hayashi：Theoretical study on ultrafast 
      time-resolved spectra of initial electron	transfer of
      photosynthetic reaction centers at low temperatures.

      12：00∼12：15  林宗義  Binding of small molecules to serum 
      albumin.

      13：00∼14：00  Poster session

      Scientific session VI X-ray crystallography（主持人：袁小琀）

      14：00∼14：50  汪必成  A	Unified	Mechanism for Modular 
      Architecture of Nucleic Acid Polymerases.

      14：50∼15：05  廖彥銓  Crystallization and X-ray	
      preliminary analysis of GAP31, CGTase,Arylesterase, Snase
      (E75G),and RC-RNase.

      15：05∼15：20  袁小琀  The structure of two Fis mutants 
      PRO61-SER	and PRO61-ALA and the interpretatin of their functions.

      15：20∼15：35  盧天惠  Structure	of abrin-a at 2.1 symbol 
      143 \f "MS LineDraw" \s 12.

      15：35∼15：50  蕭傳鐙  

      Scientific session VII Biophysical Techniques II（主持人：譚
      鳴輝）

      16：00∼16：50  鄭天佑  Least activation path (LAP) model	
      for protein folding：A kinetic investigation of in vitro
      folding of Staphylococcal	nuclease.

      16：50∼17：00  陳惠民  Effect of	Mutation of a Non-active 
      site amino acid, glutamic	acid, at position 75, on the activity
      of Staphylococcal	nuclease.

      17：00∼17：15  楊大衍  Theory of	ligand recombination of	
      myoglobin

      17：15∼17：30  譚鳴輝  Mass spectrometeric analysis of rat 
      liver and	kidney cytosolic glutathione S-transferases.

      五月十三日

      Scientific session VIII Computer Modeling（主持人：C.P. Yang）

      09：00∼09：50  Gordon M.	Crippen：Proposed rules	of the 
      protein folding game.

      09：50∼10：05  胡紀如  Phthalimidoalkyl nitrates	and 
      nitrites as novel	photo-induced DNA- cleaving agents:
      Computer modeling	studies.

      10：05∼10：20  王志鉦  Design of	pyrrol[1,4]benzodiazepines 
      hybrid antitumor agent.

      10：20∼10：35  徐令儀  Preparation of 2-hydroxylmethyl-1H,2H,
      7H-pyrimido[1,6-c][1,3]oxazine-6,8-dione,	a structural mimicry
      of anti-rigid pyrimidine acrylic nucleoside.

      10：35∼10：50  林小喬  Molecular	Dynamics of E. coli 
      ribonuclease H1 in solution, interpretation of NMR and X-ray
      data and insight into biological function.

      Scientific sessio	IX Magnetic Resonance Imaging（主持人：H. 
      Yeung）

      11：00∼11：15  鍾孝文  Mapping of magnetic field	
      distribution in human vertibral cancellous bone.

      11：15∼11：30  官偉鵬  A	surface/volume switchable (SVS)	
      radio-frequency coil for medical magnetic	resonance
      imaging/spectroscopy.

      11：30∼11：45  吳銘庭  MR velocity mapping of azygos blood 
      flow in cirrhosis: Correlation with variceal hemorrhage.

      11：45∼12：00  閉幕致辭（何潛）