{"id":8766,"date":"2021-09-23T00:03:11","date_gmt":"2021-09-22T16:03:11","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=8766"},"modified":"2024-03-13T09:19:58","modified_gmt":"2024-03-13T01:19:58","slug":"coup-tfi-specifies-the-medial-entorhinal-cortex-identity-and-induces-differential-cell-adhesion-to-determine-the-integrity-of-its-boundary-with-neocortex","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/8766\/","title":{"rendered":"COUP-TFI specifies the medial entorhinal cortex identity and induces differential cell adhesion to determine the integrity of its boundary with neocortex"},"content":{"rendered":"<p>Dr. Shen-Ju Chou\u2019s research group at Institute of Cellular and Organismic Biology, Academia Sinica, uncovered that determination of the boundary between neocortex and medial entorhinal cortex relies on COUP-TFI and they also proved that a sharp boundary requires a subtle interplay between patterning transcription factors and differential cell affinity. The research article has been published on <em>Science Advances<\/em>.<\/p>\n<p>Article Link: <a href=\"https:\/\/advances.sciencemag.org\/content\/7\/27\/eabf6808?rss=1\">https:\/\/advances.sciencemag.org\/content\/7\/27\/eabf6808?rss=1<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-large wp-image-8767 aligncenter\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11-1024x616.jpg\" alt=\"\" width=\"1024\" height=\"616\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11-1024x616.jpg 1024w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11-300x180.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11-768x462.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11-1080x650.jpg 1080w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11-627x376.jpg 627w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11-440x264.jpg 440w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-11.jpg 1395w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Shen-Ju Chou\u2019s research group at Institute of Cellular and Organismic Biology, Academia Sinica, uncovered that determination of the boundary between neocortex and medial entorhinal cortex relies on COUP-TFI and they also proved that a sharp boundary requires a subtle interplay between patterning transcription factors and differential cell affinity. The research article has been published [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8767,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[533],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8766"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=8766"}],"version-history":[{"count":2,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8766\/revisions"}],"predecessor-version":[{"id":13216,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8766\/revisions\/13216"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/8767"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=8766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=8766"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=8766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}