{"id":8763,"date":"2021-09-23T00:03:17","date_gmt":"2021-09-22T16:03:17","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=8763"},"modified":"2024-03-13T09:19:58","modified_gmt":"2024-03-13T01:19:58","slug":"molecular-insights-into-the-increased-transmissibility-and-immunity-evasion-of-the-sars-cov-2-alpha-variant","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/8763\/","title":{"rendered":"Molecular insights into the increased transmissibility and immunity evasion of the SARS-CoV-2 Alpha variant"},"content":{"rendered":"<p>Dr. Shang-Te Danny Hsu at the Institute of Biological Chemistry, Academia Sinica, used state-of-the-art cryo-electron microscopy (cryo-EM) to determine the atomic structure of the spike protein of the Alpha variant of SARS-CoV-2. Dr. Hsu also collaborate with Dr. Han-Chung Wu, Director of the Biomedical Translation Research Center and discover that the cryo-EM structure of the spike protein in complex with the two antibodies underscores the potential of their combined use as an antibody cocktail to mitigate COVID-19 caused by different SARS-CoV-2 variants.<\/p>\n<p>Article Link: <a href=\"https:\/\/www.nature.com\/articles\/s41594-021-00652-z\">https:\/\/www.nature.com\/articles\/s41594-021-00652-z<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-large wp-image-8764 aligncenter\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-1024x615.jpg\" alt=\"\" width=\"1024\" height=\"615\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-1024x615.jpg 1024w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-300x180.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-768x462.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-1080x649.jpg 1080w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-1280x768.jpg 1280w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-627x376.jpg 627w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10-440x264.jpg 440w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2021\/09\/webimage-10.jpg 1396w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Shang-Te Danny Hsu at the Institute of Biological Chemistry, Academia Sinica, used state-of-the-art cryo-electron microscopy (cryo-EM) to determine the atomic structure of the spike protein of the Alpha variant of SARS-CoV-2. Dr. Hsu also collaborate with Dr. Han-Chung Wu, Director of the Biomedical Translation Research Center and discover that the cryo-EM structure of the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8764,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[533],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8763"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=8763"}],"version-history":[{"count":2,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8763\/revisions"}],"predecessor-version":[{"id":13215,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8763\/revisions\/13215"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/8764"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=8763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=8763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=8763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}