{"id":8039,"date":"2020-12-31T00:03:06","date_gmt":"2020-12-30T16:03:06","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=8039"},"modified":"2024-03-13T09:18:15","modified_gmt":"2024-03-13T01:18:15","slug":"new-strategy-for-lung-cancer-treatments-chemotherapy-combined-with-tumor-immunotherapy","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/8039\/","title":{"rendered":"New Strategy for lung cancer treatments! Chemotherapy combined with tumor immunotherapy"},"content":{"rendered":"<p>Lung cancer is the leading cause of cancer death in Taiwan and the world, and its treatment has always been a topic of concern in the country. A research team composed of Drs. Pan-Chyr Yang (Academician of Academia Sinica), Shu-Ping Wang (Assistant Research Fellow) and Chia-Sing Lu (Postdoctoral Fellow) of the Institute of Biomedical Sciences, found that the chemotherapeutic agent \u201cPemetrexed\u201d can trigger the TS-ROS-NF-kB regulatory axis to activate the expression of PD-L1 in lung cancer cells, thereby creating a favorable tumor microenvironment for immunotherapy. The combined use of this chemotherapy and immunotherapy can become the first-line treatment for advanced lung cancer.<\/p>\n<p>Link of Article: <a href=\"https:\/\/jitc.bmj.com\/content\/8\/2\/e001392\">https:\/\/jitc.bmj.com\/content\/8\/2\/e001392<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2020\/12\/\u6f2b\u6b65\u79d1\u7814_\u80ba\u764c\u6cbb\u7642\u65b0\u9078\u64c7\u4fee.jpg\" alt=\"\" width=\"836\" height=\"504\" class=\"aligncenter size-full wp-image-8040\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2020\/12\/\u6f2b\u6b65\u79d1\u7814_\u80ba\u764c\u6cbb\u7642\u65b0\u9078\u64c7\u4fee.jpg 836w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2020\/12\/\u6f2b\u6b65\u79d1\u7814_\u80ba\u764c\u6cbb\u7642\u65b0\u9078\u64c7\u4fee-300x181.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2020\/12\/\u6f2b\u6b65\u79d1\u7814_\u80ba\u764c\u6cbb\u7642\u65b0\u9078\u64c7\u4fee-768x463.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2020\/12\/\u6f2b\u6b65\u79d1\u7814_\u80ba\u764c\u6cbb\u7642\u65b0\u9078\u64c7\u4fee-440x264.jpg 440w\" sizes=\"(max-width: 836px) 100vw, 836px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lung cancer is the leading cause of cancer death in Taiwan and the world, and its treatment has always been a topic of concern in the country. A research team composed of Drs. Pan-Chyr Yang (Academician of Academia Sinica), Shu-Ping Wang (Assistant Research Fellow) and Chia-Sing Lu (Postdoctoral Fellow) of the Institute of Biomedical Sciences, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8041,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[535],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8039"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=8039"}],"version-history":[{"count":2,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8039\/revisions"}],"predecessor-version":[{"id":13106,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/8039\/revisions\/13106"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/8041"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=8039"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=8039"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=8039"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}