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A multinational team comprising of Todor Dudev, Karine Mazmanian, Felix Weng, Cedric Grauffel led by Carmay Lim, Distinguished Research Fellow at the Institute of Biomedical Sciences, has explored this question in a recent publication in Accounts of Chemical Research<\/em>. They have provided a unifying physicochemical basis that underlies lithium\u2019s multifaceted effects based on its competition as a free monocation with native cations in proteins and as a phosphate-bound polyanionic complex modulating the host protein function.<\/p>\n
Article Link: https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31556294<\/a><\/p>\n