{"id":6340,"date":"2019-10-31T00:01:58","date_gmt":"2019-10-30T16:01:58","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=6340"},"modified":"2024-03-13T09:18:15","modified_gmt":"2024-03-13T01:18:15","slug":"how-can-li-a-monocation-with-only-2-electrons-prevent-suicide-and-bipolar-recurrence","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/6340\/","title":{"rendered":"How can Li+, a monocation with only 2 electrons, prevent suicide and bipolar recurrence?"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-6341\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2019\/10\/3-4\u6f2b\u6b65\u79d1\u7814-\u92f0\u96e2\u5b50\u5982\u4f55\u9810\u9632\u81ea\u6bba\u8207\u8e81\u9b31\u75c7.jpg\" alt=\"\" width=\"627\" height=\"401\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2019\/10\/3-4\u6f2b\u6b65\u79d1\u7814-\u92f0\u96e2\u5b50\u5982\u4f55\u9810\u9632\u81ea\u6bba\u8207\u8e81\u9b31\u75c7.jpg 835w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2019\/10\/3-4\u6f2b\u6b65\u79d1\u7814-\u92f0\u96e2\u5b50\u5982\u4f55\u9810\u9632\u81ea\u6bba\u8207\u8e81\u9b31\u75c7-300x192.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2019\/10\/3-4\u6f2b\u6b65\u79d1\u7814-\u92f0\u96e2\u5b50\u5982\u4f55\u9810\u9632\u81ea\u6bba\u8207\u8e81\u9b31\u75c7-768x491.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2019\/10\/3-4\u6f2b\u6b65\u79d1\u7814-\u92f0\u96e2\u5b50\u5982\u4f55\u9810\u9632\u81ea\u6bba\u8207\u8e81\u9b31\u75c7-430x275.jpg 430w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2019\/10\/3-4\u6f2b\u6b65\u79d1\u7814-\u92f0\u96e2\u5b50\u5982\u4f55\u9810\u9632\u81ea\u6bba\u8207\u8e81\u9b31\u75c7-516x330.jpg 516w\" sizes=\"(max-width: 627px) 100vw, 627px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>A multinational team comprising of Todor Dudev, Karine Mazmanian, Felix Weng, Cedric Grauffel led by Carmay Lim, Distinguished Research Fellow at the Institute of Biomedical Sciences, has explored this question in a recent publication in <em>Accounts of Chemical Research<\/em>. They have provided a unifying physicochemical basis that underlies lithium\u2019s multifaceted effects based on its competition as a free monocation with native cations in proteins and as a phosphate-bound polyanionic complex modulating the host protein function.<\/p>\n<p>Article Link: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31556294\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31556294<\/a><\/p>\n<p style=\"text-align: right;\">\uff08\u7d30\u80de\u8207\u500b\u9ad4\u751f\u7269\u5b78\u7814\u7a76\u6240\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; A multinational team comprising of Todor Dudev, Karine Mazmanian, Felix Weng, Cedric Grauffel led by Carmay Lim, Distinguished Research Fellow at the Institute of Biomedical Sciences, has explored this question in a recent publication in Accounts of Chemical Research. They have provided a unifying physicochemical basis that underlies lithium\u2019s multifaceted effects based on its [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":6341,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[535],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/6340"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=6340"}],"version-history":[{"count":2,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/6340\/revisions"}],"predecessor-version":[{"id":13120,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/6340\/revisions\/13120"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/6341"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=6340"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=6340"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=6340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}