{"id":12637,"date":"2023-10-19T00:02:15","date_gmt":"2023-10-18T16:02:15","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=12637"},"modified":"2024-03-13T09:19:02","modified_gmt":"2024-03-13T01:19:02","slug":"the-counter-defense-between-fungal-and-plant-pr-1-family-proteins","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/12637\/","title":{"rendered":"The counter defense between fungal and plant PR-1 family proteins"},"content":{"rendered":"<p>A new finding has elucidated the co-evolutionary arms race between fungal pathogens and their host plants. Dr. Lay-Sun Ma at the Institute of Plant and Microbial Biology, Academia Sinica and her collaborators, Dr. Yin-Ru Chiang and Dr. Chuan-Chih Hsu, disclosed how the corn smut pathogen <em>Ustilago maydis<\/em> thrives on infecting its host. The process involves a sophisticated counter defense between two structurally conserved proteins, plant pathogenesis-related PR-1 for plant defense and fungal PR-1-like (PR-1L) proteins for fungal virulence, respectively. By producing PR-1L proteins, <em>U. maydis<\/em> confers resistance to toxic plant phenolics. <em>U. maydis<\/em> also hijacks the corn protease CatB3 to release a mimetic peptide from PR-1L to counteract the immunity-triggering peptide derived from the plant PR-1. This process suppresses plant immunity, enabling successful colonization of the fungus. These findings fill the knowledge gap of fungal parasitism in crops and the co-evolutionary dynamics of PR-1L and PR-1 protein in pathogens and their hosts, enabling the strategic improvement of crops to combat fungal pathogens. This study has been published in the journal <em>Nature Communications<\/em> (September 2023).<\/p>\n<p>Article link: <a href=\"https:\/\/www.nature.com\/articles\/s41467-023-41459-4\" rel=\"noopener\" target=\"_blank\">https:\/\/www.nature.com\/articles\/s41467-023-41459-4<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/10\/3-1-1.jpg\" alt=\"The counter defense between fungal and plant PR-1 family proteins\" width=\"1920\" height=\"1141\" class=\"aligncenter size-full wp-image-12638\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/10\/3-1-1.jpg 1920w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/10\/3-1-1-300x178.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/10\/3-1-1-1024x609.jpg 1024w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/10\/3-1-1-768x456.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/10\/3-1-1-1536x913.jpg 1536w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/10\/3-1-1-1080x642.jpg 1080w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new finding has elucidated the co-evolutionary arms race between fungal pathogens and their host plants. Dr. Lay-Sun Ma at the Institute of Plant and Microbial Biology, Academia Sinica and her collaborators, Dr. Yin-Ru Chiang and Dr. Chuan-Chih Hsu, disclosed how the corn smut pathogen Ustilago maydis thrives on infecting its host. The process involves [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":12639,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[533],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/12637"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=12637"}],"version-history":[{"count":1,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/12637\/revisions"}],"predecessor-version":[{"id":13133,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/12637\/revisions\/13133"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/12639"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=12637"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=12637"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=12637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}