{"id":11385,"date":"2023-03-09T00:02:18","date_gmt":"2023-03-08T16:02:18","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=11385"},"modified":"2023-04-20T00:43:47","modified_gmt":"2023-04-19T16:43:47","slug":"new-fellow-introduction-dr-cheng-yang-assistant-research-fellow-of-the-institute-of-biomedical-sciences","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/11385\/","title":{"rendered":"New Fellow Introduction: Dr. Cheng Yang, Assistant Research Fellow of the Institute of Biomedical Sciences"},"content":{"rendered":"<p>Dr. Cheng Yang started his pre-doctoral training with Dr. Matthias von Herrath in La Jolla Institute and Dr. Mala Maini in University College London, where he gained extensive experience in the modulation of antigen-specific T cells in the context of type 1 diabetes, chronic LCMV and hepatitis B virus (HBV) infection. <\/p>\n<p>During his doctoral and the first post-doctoral training at Singapore Immunology Network of A*STAR with Dr. Evan Newell, his research was focused on deep-profiling human virus-specific T cells in chronic HBV infection and HBV-associated liver disease and cancer using highly multiplexed combinatorial peptide-MHC tetramer staining, mass cytometry, single-cell multi-omics, and high-dimensional analysis. <\/p>\n<p>Dr. Cheng discovered several novel T cell epitopes targeting HBV and HBV-reactive TCRs that can be used for immunotherapeutics. He and his research group found that HBV-specific memory T cell, or tumor-infiltrating tissue-resident memory HBV-specific T cell responses were linked to the patients\u2019 improved clinical outcomes. <\/p>\n<p>Dr. Cheng continued his human immunology research in Massachusetts General Hospital at Harvard Medical School as a Senior Research Scientist, exploring the tissue-resident memory human papillomavirus (HPV)-specific T cell responses in patients with HPV-associated diseases.<\/p>\n<p>Dr. Cheng Yang joined the Institute of Biomedical Sciences as an Assistant Research Fellow in January, 2023. <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-1024x615.jpg\" alt=\"New Fellow Introduction: Dr. Cheng Yang, Assistant Research Fellow of the Institute of Biomedical Sciences\" width=\"1024\" height=\"615\" class=\"aligncenter size-large wp-image-11386\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-1024x615.jpg 1024w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-300x180.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-768x461.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-1080x649.jpg 1080w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-1280x768.jpg 1280w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-627x376.jpg 627w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E-440x264.jpg 440w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/03\/web-1785_4-4_E.jpg 1395w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Cheng Yang started his pre-doctoral training with Dr. Matthias von Herrath in La Jolla Institute and Dr. Mala Maini in University College London, where he gained extensive experience in the modulation of antigen-specific T cells in the context of type 1 diabetes, chronic LCMV and hepatitis B virus (HBV) infection. During his doctoral and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":11386,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[427],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11385"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=11385"}],"version-history":[{"count":1,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11385\/revisions"}],"predecessor-version":[{"id":11387,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11385\/revisions\/11387"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/11386"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=11385"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=11385"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=11385"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}