{"id":11126,"date":"2023-02-09T00:03:22","date_gmt":"2023-02-08T16:03:22","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=11126"},"modified":"2024-03-13T09:19:03","modified_gmt":"2024-03-13T01:19:03","slug":"structural-basis-for-a-conserved-neutralization-epitope-on-the-receptor-binding-domain-of-sars-cov-2","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/11126\/","title":{"rendered":"Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2"},"content":{"rendered":"<p>The COVID-19 pandemic seems to be fading away from our daily life, but the threat of a recurring circulation of new variants still haunts. While the vaccines continue being developed for a preventive purpose, the neutralizing antibodies stand in the last line of defense as a therapeutic tool. In the latest publication on &#8220;Nature Communications&#8221;, exciting findings were reported by a collaborative team led by Dr. Che Ma in the Genomics Research Center and Dr. Kuan-Ying Huang in the National Taiwan University Hospital. From the locally recruited individuals in Taiwan, they identified a panel of eight monoclonal antibodies that are all targeting a cryptic yet conserved epitope of the receptor binding domain (RBD) of the surface Spike protein of SARS-CoV-2.<\/p>\n<p>Website:<a href=\"https:\/\/www.genomics.sinica.edu.tw\/index.php\/en\/news\/lastest-news\/712-2023-01-30-02-18-02\"> https:\/\/www.genomics.sinica.edu.tw\/index.php\/en\/news\/lastest-news\/712-2023-01-30-02-18-02<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/02\/3-2.jpg\" alt=\"Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2\" width=\"836\" height=\"504\" class=\"aligncenter size-full wp-image-11127\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/02\/3-2.jpg 836w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/02\/3-2-300x181.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/02\/3-2-768x463.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/02\/3-2-440x264.jpg 440w\" sizes=\"(max-width: 836px) 100vw, 836px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The COVID-19 pandemic seems to be fading away from our daily life, but the threat of a recurring circulation of new variants still haunts. While the vaccines continue being developed for a preventive purpose, the neutralizing antibodies stand in the last line of defense as a therapeutic tool. In the latest publication on &#8220;Nature Communications&#8221;, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":11128,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[533],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11126"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=11126"}],"version-history":[{"count":2,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11126\/revisions"}],"predecessor-version":[{"id":13157,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11126\/revisions\/13157"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/11128"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=11126"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=11126"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=11126"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}