{"id":10769,"date":"2022-12-01T00:03:07","date_gmt":"2022-11-30T16:03:07","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=10769"},"modified":"2024-03-13T09:19:03","modified_gmt":"2024-03-13T01:19:03","slug":"detecting-different-rnas-in-the-same-cell","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/10769\/","title":{"rendered":"Detecting different RNAs in the same cell"},"content":{"rendered":"<p>In biological study, one sometimes needs to detect the simultaneous presence of a micro RNA (miRNA) and its putative target mRNA in the same cell. As no such technique is unavailable, <a href=\"https:\/\/www.biodiv.tw\/pi-Wen-Hsiung_Li\">Dr. Wen-Hsiung Li<\/a>\u2019s team at Biodiversity Research Center develop a in situ method for this purpose. It uses rolling-circle amplification of RNAs to achieve a high signal\/noise ratio. It can be applied to simultaneous detection of multiple RNAs in the same cell. The results were published in <em>Plant Biotechnology Journal<\/em>.<\/p>\n<p>For further information: <a href=\"https:\/\/www.biodiv.tw\/research-20221110155931\">https:\/\/www.biodiv.tw\/research-20221110155931<\/a><br \/>\nArticle link: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/pbi.13931\">https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/pbi.13931<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2022\/11\/3-3-1024x769.jpg\" alt=\"Detecting different RNAs in the same cell\" width=\"1024\" height=\"769\" class=\"alignnone size-large wp-image-10770\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2022\/11\/3-3-1024x769.jpg 1024w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2022\/11\/3-3-300x225.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2022\/11\/3-3-768x577.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2022\/11\/3-3-1080x811.jpg 1080w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2022\/11\/3-3.jpg 1477w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In biological study, one sometimes needs to detect the simultaneous presence of a micro RNA (miRNA) and its putative target mRNA in the same cell. As no such technique is unavailable, Dr. Wen-Hsiung Li\u2019s team at Biodiversity Research Center develop a in situ method for this purpose. It uses rolling-circle amplification of RNAs to achieve [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10771,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[533],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/10769"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=10769"}],"version-history":[{"count":2,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/10769\/revisions"}],"predecessor-version":[{"id":13166,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/10769\/revisions\/13166"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/10771"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=10769"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=10769"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=10769"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}