{"id":32726,"date":"2023-10-19T00:10:47","date_gmt":"2023-10-18T16:10:47","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=32726"},"modified":"2023-10-19T00:27:42","modified_gmt":"2023-10-18T16:27:42","slug":"%e7%9c%9f%e8%8f%8c%e8%88%87%e6%a4%8d%e7%89%a9%e5%ae%bf%e4%b8%bb-pr-1-%e9%98%b2%e7%a6%a6%e8%9b%8b%e7%99%bd%e5%ae%b6%e6%97%8f%e7%9a%84%e6%94%bb%e9%98%b2%e6%88%b0","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/32726\/","title":{"rendered":"\u771f\u83cc\u8207\u690d\u7269\u5bbf\u4e3b PR-1 \u9632\u79a6\u86cb\u767d\u5bb6\u65cf\u7684\u653b\u9632\u6230"},"content":{"rendered":"<p>\u4f5c\u7269\u8207\u75c5\u539f\u83cc\u4e4b\u9593\u6709\u6c38\u4e0d\u505c\u6b47\u7684\u653b\u9632\u6230\uff0c\u690d\u7269\u5728\u4e0d\u65b7\u5f37\u5316\u5c0d\u75c5\u539f\u83cc\u7684\u514d\u75ab\u529b\u7684\u540c\u6642\uff0c\u75c5\u539f\u83cc\u4e5f\u4e00\u76f4\u8a2d\u6cd5\u7a81\u7834\u690d\u7269\u7684\u62b5\u79a6\u9632\u7dda\u3002\u9019\u500b\u653b\u9632\u6230\u4e2d\u5305\u542b\u4e00\u7fa4\u540c\u6642\u51fa\u73fe\u5728\u771f\u83cc\u8207\u5bbf\u4e3b\u4e2d\u7684\u540c\u6e90 PR-1 \u86cb\u767d\u8cea\uff0c\u9019\u7fa4\u86cb\u767d\u8cea\u5728\u690d\u7269\u7684\u529f\u80fd\u662f\u589e\u52a0\u9632\u79a6\u529b\uff0c\u4f46\u5728\u771f\u83cc\u4e2d\u537b\u53ef\u589e\u52a0\u5c0d\u5bbf\u4e3b\u7684\u611f\u67d3\u529b\u3002\u672c\u9662\u690d\u7269\u66a8\u5fae\u751f\u7269\u5b78\u7814\u7a76\u6240\u99ac\u9e97\u73ca\u52a9\u7814\u7a76\u54e1\u3001\u8a31\u5168\u667a\u535a\u58eb\u548c\u751f\u7269\u591a\u6a23\u6027\u7814\u7a76\u4e2d\u5fc3\u6c5f\u6bb7\u5112\u7814\u7a76\u54e1\u5718\u968a\u5408\u4f5c\u767c\u73fe\uff1a\u7389\u7c73\u9ed1\u7c89\u83cc\u5167\u985e\u4f3c\u5bbf\u4e3b PR-1 \u7684\u86cb\u767d\u8cea\uff08PR-1-like; PR-1L\uff09\u53ef\u4ee5\u611f\u77e5\u690d\u7269\u91cb\u653e\u51fa\u7684\u6709\u6bd2\u915a\u985e\u5316\u5408\u7269\uff0c\u9032\u800c\u5305\u8986\u83cc\u7d72\u4ee5\u62b5\u6297\u915a\u985e\u5316\u5408\u7269\u3002\u771f\u83cc\u4e5f\u540c\u6642\u5229\u7528\u5bbf\u4e3b\u86cb\u767d\u9176 CatB3 \u5c07 PR-1 \uff2c \u5206\u89e3\u4e26\u91cb\u653e\u51fa\u985e\u4f3c\u6e90\u81ea\u690d\u7269\u5bbf\u4e3b PR-1 \u9632\u79a6\u86cb\u767d\u7684\u5c0f\u578b\u80dc\u80bd\uff0c\u85c9\u7531\u6df7\u6dc6\u5bbf\u4e3b\u7684\u514d\u75ab\u53d7\u9ad4\uff0c\u4f86\u6291\u5236\u690d\u7269\u514d\u75ab\u529b\uff0c\u8b93\u7389\u7c73\u9ed1\u7c89\u83cc\u53ef\u4ee5\u9806\u5229\u5728\u5bbf\u4e3b\u4e2d\u751f\u5b58\u3002\u9019\u500b\u7814\u7a76\u9996\u5ea6\u63ed\u793a\u771f\u83cc\u5bc4\u751f\u53ca\u8207\u5bbf\u4e3b\u4e4b\u9593\u85c9\u7531\u540c\u6e90\u86cb\u767d\u8cea\u7684\u5171\u540c\u6f14\u5316\u6240\u7522\u751f\u7684\u5de7\u5999\u653b\u9632\u7b56\u7565\uff0c\u76f8\u95dc\u6210\u679c\u4e5f\u53ef\u904b\u7528\u5728\u5f37\u5316\u4f5c\u7269\u5c0d\u771f\u83cc\u75c5\u539f\u9ad4\u7684\u62b5\u79a6\u529b\u3002\u6b64\u7814\u7a76\u6210\u679c\u5df2\u65bc\u672c\uff082023\uff09\u5e74 9 \u6708\u520a\u767b\u65bc\u300a\u81ea\u7136\u901a\u8a0a\u300b\uff08<em>Nature Communications<\/em>\uff09\u3002<\/p>\n<p>\u8ad6\u6587\u5168\u6587\uff1a <a href=\"https:\/www.nature.com\/articles\/s41467-023-41459-4\" rel=\"noopener\" target=\"_blank\">https:\/www.nature.com\/articles\/s41467-023-41459-4<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/10\/3-1-1.jpg\" alt=\"\u771f\u83cc\u8207\u690d\u7269\u5bbf\u4e3b PR-1 \u9632\u79a6\u86cb\u767d\u5bb6\u65cf\u7684\u653b\u9632\u6230\" width=\"1920\" height=\"1141\" class=\"aligncenter size-full wp-image-32728\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/10\/3-1-1.jpg 1920w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/10\/3-1-1-300x178.jpg 300w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/10\/3-1-1-1024x609.jpg 1024w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/10\/3-1-1-768x456.jpg 768w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/10\/3-1-1-1536x913.jpg 1536w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/10\/3-1-1-1080x642.jpg 1080w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f5c\u7269\u8207\u75c5\u539f\u83cc\u4e4b\u9593\u6709\u6c38\u4e0d\u505c\u6b47\u7684\u653b\u9632\u6230\uff0c\u690d\u7269\u5728\u4e0d\u65b7\u5f37\u5316\u5c0d\u75c5\u539f\u83cc\u7684\u514d\u75ab\u529b\u7684\u540c\u6642\uff0c\u75c5\u539f\u83cc\u4e5f\u4e00\u76f4\u8a2d\u6cd5\u7a81\u7834\u690d\u7269\u7684\u62b5\u79a6\u9632\u7dda\u3002 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":32727,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[988,984],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/32726"}],"collection":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/comments?post=32726"}],"version-history":[{"count":1,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/32726\/revisions"}],"predecessor-version":[{"id":32805,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/posts\/32726\/revisions\/32805"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media\/32727"}],"wp:attachment":[{"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/media?parent=32726"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/categories?post=32726"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/newsletter.sinica.edu.tw\/wp-json\/wp\/v2\/tags?post=32726"}],"curies":[{"name":"wp","href":"https:\/api.w.org\/{rel}","templated":true}]}}