{"id":32463,"date":"2023-09-21T00:15:02","date_gmt":"2023-09-20T16:15:02","guid":{"rendered":"https:\/newsletter.sinica.edu.tw\/?p=32463"},"modified":"2023-09-21T00:16:14","modified_gmt":"2023-09-20T16:16:14","slug":"%e8%87%aa%e9%96%89%e7%97%87%e5%9f%ba%e5%9b%a0%e6%8e%a7%e5%88%b6%e7%a5%9e%e7%b6%93%e7%aa%81%e8%a7%b8%e5%8f%af%e5%a1%91%e6%80%a7-%e8%b6%85%e8%a7%a3%e6%9e%90%e5%85%89%e5%ad%b8%e9%a1%af%e5%be%ae","status":"publish","type":"post","link":"https:\/newsletter.sinica.edu.tw\/32463\/","title":{"rendered":"\u81ea\u9589\u75c7\u57fa\u56e0\u63a7\u5236\u795e\u7d93\u7a81\u89f8\u53ef\u5851\u6027\u2014\u8d85\u89e3\u6790\u5149\u5b78\u986f\u5fae\u6280\u8853\u4e4b\u61c9\u7528"},"content":{"rendered":"<p>\u672c\u9662\u5206\u5b50\u751f\u7269\u7814\u7a76\u6240\u859b\u4e00\u860b\u7279\u8058\u7814\u7a76\u54e1\u5be6\u9a57\u5ba4\uff0c\u5229\u7528\u9ad8\u968e\u5149\u5b78\u986f\u5fae\u93e1\u6280\u8853\u8207\u751f\u5316\u5206\u6790\uff0c\u8b49\u5be6 KLHL17 \u548c SYNPO \u5169\u500b\u81ea\u9589\u75c7\u81f4\u75c5\u86cb\u767d\u8cea\uff0c\u53ef\u5354\u540c\u8abf\u63a7\u795e\u7d93\u5143\u7a81\u89f8\uff08synapse\uff09\u88e1\u9762\u7684\u68d8\u5668\uff08spine apparatus\uff09\u3002\u68d8\u5668\u662f\u8208\u596e\u6027\u7a81\u89f8\u5167\u90e8\u7279\u5316\u7684\u5167\u8cea\u7db2\uff0c\u63a7\u5236\u9223\u96e2\u5b50\u6d41\u901a\u548c\u7a81\u89f8\u53ef\u5851\u6027\u3002KLHL17 \u548c SYNPO \u5728\u7a81\u89f8\u5167\u4fc3\u9032\u68d8\u5668\u805a\u96c6\uff0c\u8abf\u63a7\u68d8\u5668\u5728\u7a81\u89f8\u5167\u7684\u6578\u91cf\u8207\u5206\u4f48\uff0c\u5f71\u97ff\u9223\u96e2\u5b50\u6d41\u901a\uff0c\u589e\u9032\u795e\u7d93\u5143\u7684\u6d3b\u6027\u8207\u53ef\u5851\u6027\u3002\u7814\u7a76\u5718\u968a\u9032\u4e00\u6b65\u8207\u672c\u9662\u61c9\u7528\u79d1\u5b78\u4e2d\u5fc3\u9673\u58c1\u5f70\u526f\u7814\u7a76\u54e1\u5be6\u9a57\u5ba4\u8de8\u9818\u57df\u5408\u4f5c\uff0c\u5229\u7528\u300c\u65b0\u5275\u6539\u826f\u64f4\u5c55\u986f\u5fae\u93e1\u6280\u8853\u300d\u7a81\u7834\u5149\u5b78\u986f\u5fae\u93e1\u7e5e\u5c04\u6975\u9650\uff0c\u4ee5\u8fd1 30 \u5948\u7c73\u8d85\u9ad8\u89e3\u6790\u5ea6\uff0c\u6210\u529f\u89c0\u5bdf KLHL17\u3001SYNPO \u8207\u68d8\u5668\u7684\u4e09\u7dad\u7a7a\u9593\u5206\u4f48\uff0c\u806f\u7d50\u68d8\u5668\u529f\u80fd\u548c\u81ea\u9589\u75c7\u7684\u76f8\u95dc\u6027\u3002\u6b64\u7814\u7a76\u6210\u679c\u5df2\u65bc\u672c\uff082023\uff09\u5e74 8 \u6708\u520a\u767b\u65bc\u300a\u516c\u5171\u79d1\u5b78\u5716\u66f8\u9928\u751f\u7269\u5b78\u671f\u520a\u300b\uff08<em>PLOS Biology<\/em>\uff09\u3002<\/p>\n<p>\u8ad6\u6587\u5168\u6587\uff1a <a href=\"https:\/journals.plos.org\/plosbiology\/article?id=10.1371\/journal.pbio.3002274\" rel=\"noopener\" target=\"_blank\">https:\/journals.plos.org\/plosbiology\/article?id=10.1371\/journal.pbio.3002274<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/09\/3-1.jpg\" alt=\"\u81ea\u9589\u75c7\u57fa\u56e0\u63a7\u5236\u795e\u7d93\u7a81\u89f8\u53ef\u5851\u6027\u2014\u8d85\u89e3\u6790\u5149\u5b78\u986f\u5fae\u6280\u8853\u4e4b\u61c9\u7528\" width=\"1920\" height=\"1280\" class=\"aligncenter size-full wp-image-32464\" srcset=\"https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/09\/3-1.jpg 1920w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/09\/3-1-300x200.jpg 300w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/09\/3-1-1024x683.jpg 1024w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/09\/3-1-768x512.jpg 768w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/09\/3-1-1536x1024.jpg 1536w, https:\/newsletter.sinica.edu.tw\/wp-content\/uploads\/2023\/09\/3-1-1080x720.jpg 1080w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u9662\u5206\u5b50\u751f\u7269\u7814\u7a76\u6240\u859b\u4e00\u860b\u7279\u8058\u7814\u7a76\u54e1\u5be6\u9a57\u5ba4\uff0c\u5229\u7528\u9ad8\u968e\u5149\u5b78\u986f\u5fae\u93e1\u6280\u8853\u8207\u751f\u5316\u5206\u6790\uff0c\u8b49\u5be6 KLHL17 \u548c SYNPO 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