{"id":11592,"date":"2023-04-20T00:05:02","date_gmt":"2023-04-19T16:05:02","guid":{"rendered":"https:\/\/newsletter.sinica.edu.tw/en\/?p=11592"},"modified":"2024-03-13T09:19:02","modified_gmt":"2024-03-13T01:19:02","slug":"structure-of-the-heterotrimeric-membrane-protein-complex-ftsb-ftsl-ftsq-of-the-bacterial-divisome","status":"publish","type":"post","link":"https:\/\/newsletter.sinica.edu.tw/en\/11592\/","title":{"rendered":"Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome"},"content":{"rendered":"<p>Membrane protein FtsB-FtsL-FtsQ (FtsBLQ) complex are essential component of divisome, which play important roles in the divisome assembling and the division-mediated peptidoglycan synthesis regulation, yet with the unclear mechanism. In the latest publication in Nature Communications, a crystal structure of the trimeric FtsB-FtsL-FtsQ complex was revealed for the first time, from a fruitful collaboration between Dr. Che Alex Ma\u2019s lab in the Genomics Research Center and Dr. Yu-Ling Shih\u2019s lab in the Institute of Biological Chemistry. A structure-based model that delineates the mechanism of the regulation of peptidoglycan synthases by the FtsBLQ complex were also proposed accordingly in this study.<\/p>\n<p>Article Link: <a href=\"https:\/\/www.nature.com\/articles\/s41467-023-37543-4\">https:\/\/www.nature.com\/articles\/s41467-023-37543-4<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/04\/3-2.jpg\" alt=\"Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome\" width=\"836\" height=\"504\" class=\"aligncenter size-full wp-image-11593\" srcset=\"https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/04\/3-2.jpg 836w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/04\/3-2-300x181.jpg 300w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/04\/3-2-768x463.jpg 768w, https:\/\/newsletter.sinica.edu.tw/en\/wp-content\/uploads\/2023\/04\/3-2-440x264.jpg 440w\" sizes=\"(max-width: 836px) 100vw, 836px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Membrane protein FtsB-FtsL-FtsQ (FtsBLQ) complex are essential component of divisome, which play important roles in the divisome assembling and the division-mediated peptidoglycan synthesis regulation, yet with the unclear mechanism. In the latest publication in Nature Communications, a crystal structure of the trimeric FtsB-FtsL-FtsQ complex was revealed for the first time, from a fruitful collaboration between [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":11594,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[533],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11592"}],"collection":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/comments?post=11592"}],"version-history":[{"count":2,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11592\/revisions"}],"predecessor-version":[{"id":13150,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/posts\/11592\/revisions\/13150"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media\/11594"}],"wp:attachment":[{"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/media?parent=11592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/categories?post=11592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.sinica.edu.tw/en\/wp-json\/wp\/v2\/tags?post=11592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}