時間： 2023 年 9 月 12 日（星期二） 14 時至 16 時
地點： 本院物理研究所 1 樓演講廳
主講人： 羅健榮教授（國立中央大學物理學系）
主持人： 林耿慧副研究員（本院物理研究所）
活動網址： https://www.phys.sinica.edu.tw/lecture_detail.php?id=2761&eng=T
聯絡人： 鍾艾庭（02）2789-8365 aiting@gate.sinica.edu.tw
摘要：
Many species of bacteria use flagella to swim. A flagellum consists of a bacterial flagellar motor (BFM), a hook, and a flagellar filament. The BFM is a natural rotary molecular machine that rotates at several hundred hertz driven by an electrochemical ion gradient. The motor consists of a rotor 50 nm in diameter surrounded by about 11 ion-conducting stator units, which exchange between motors and a membrane-bound pool. Bacterial flagella are dynamic, not only because they rotate and reverse, but also because some of their components exchange on a short time scale. These components’ exchange may contribute to regulatory control, functional adaptation, and system repair.

In this talk, Dr. Lo will present the current understanding of BFM and the newly emerging picture of protein complex exchange. It is necessary to replace a binary distinction between stable complexes and transient binding partners with a description of the lifetime and exchange dynamics of each individual protein associated with a complex.